U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

CG3436 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 33180, updated on 10-May-2024

Summary

Go to the top of the page Help
Official Symbol
CG3436provided by FlyBase
Primary source
FLYBASE:FBgn0031229
Locus tag
Dmel_CG3436
See related
AllianceGenome:FB:FBgn0031229
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG3436
Summary
Predicted to enable RNA binding activity. Involved in mitotic cell cycle. Part of catalytic step 2 spliceosome and precatalytic spliceosome. Is expressed in several structures, including anterior endoderm anlage; embryonic/larval nervous system; extended germ band embryo; germ layer; and presumptive embryonic/larval system. Orthologous to human SNRNP40 (small nuclear ribonucleoprotein U5 subunit 40). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
21B3-21B3; 2-0.5 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (156029..157666)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (156029..157666)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene NADH dehydrogenase (ubiquinone) 15 kDa subunit Neighboring gene uncharacterized protein Neighboring gene Pseudouridine synthase 10 Neighboring gene uncharacterized protein Neighboring gene split ends

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Genome-wide DNA replication profile for Drosophila melanogaster: a link between transcription and replication timing. Schübeler D, et al. Nat Genet, 2002 Nov. PMID 12355067
  2. Drosophila valois encodes a divergent WD protein that is required for Vasa localization and Oskar protein accumulation. Cavey M, et al. Development, 2005 Feb. PMID 15634703
  3. Drosophila MFAP1 is required for pre-mRNA processing and G2/M progression. Andersen DS, et al. J Biol Chem, 2008 Nov 7. PMID 18765666, Free PMC Article
  4. Regulation of microtubule assembly and organization in mitosis by the AAA+ ATPase Pontin. Ducat D, et al. Mol Biol Cell, 2008 Jul. PMID 18463163, Free PMC Article
  5. The Output of Protein-Coding Genes Shifts to Circular RNAs When the Pre-mRNA Processing Machinery Is Limiting. Liang D, et al. Mol Cell, 2017 Dec 7. PMID 29174924, Free PMC Article

See all (35) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

Go to the top of the page

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables RNA binding ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in mRNA splicing, via spliceosome IC
Inferred by Curator
more info
 PubMed 
involved_in mitotic cell cycle HMP PubMed 
Component Evidence Code Pubs
part_of catalytic step 2 spliceosome HDA PubMed 
part_of catalytic step 2 spliceosome IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of precatalytic spliceosome HDA PubMed 

General protein information

Go to the top of the page Help
Preferred Names
uncharacterized protein
Names
CG3436-PA
CG3436-PC

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    156029..157666
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001298614.1 → NP_001285543.1  uncharacterized protein Dmel_CG3436, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001285543.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VPL0
    Conserved Domains (3) summary
    COG2319
    Location:19 → 346
    WD40; WD40 repeat [General function prediction only]
    cd00200
    Location:50 → 342
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    sd00039
    Location:58 → 96
    7WD40; WD40 repeat [structural motif]

  2. NM_134657.3 → NP_608501.1  uncharacterized protein Dmel_CG3436, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_608501.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VPL0
    Related
    FBpp0077778
    Conserved Domains (3) summary
    COG2319
    Location:19 → 346
    WD40; WD40 repeat [General function prediction only]
    cd00200
    Location:50 → 342
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    sd00039
    Location:58 → 96
    7WD40; WD40 repeat [structural motif]
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VPL0 Q9VPL0

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools
Miscellaneous