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CG9577 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 33016, updated on 26-Apr-2024

Summary

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Official Symbol
CG9577provided by FlyBase
Primary source
FLYBASE:FBgn0031092
Locus tag
Dmel_CG9577
See related
AllianceGenome:FB:FBgn0031092
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG9577; Ech1; ECH1
Summary
Predicted to enable delta3,5-delta2,4-dienoyl-CoA isomerase activity. Predicted to be located in peroxisome. Predicted to be active in mitochondrion. Is expressed in several structures, including adult head; adult heart; embryonic/larval muscle system; gut section; and wing disc. Orthologous to human ECH1 (enoyl-CoA hydratase 1). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
19C1-19C1; 1-64 cM
Exon count:
4
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (20166673..20168080)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (20060706..20062113)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene Rab35 Neighboring gene PHD finger protein 7 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Annexin B10 Neighboring gene Sperm-specific dynein intermediate chain 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. O-GlcNAcylation of boundary element associated factor (BEAF 32) in Drosophila melanogaster correlates with active histone marks at the promoters of its target genes. De D, et al. Nucleus, 2018 Jan 1. PMID 28910574, Free PMC Article
  2. miR-125-chinmo pathway regulates dietary restriction-dependent enhancement of lifespan in Drosophila. Pandey M, et al. Elife, 2021 Jun 8. PMID 34100717, Free PMC Article
  3. The Stearoyl-CoA Desaturase-1 (Desat1) in Drosophila cooperated with Myc to Induce Autophagy and Growth, a Potential New Link to Tumor Survival. Paiardi C, et al. Genes (Basel), 2017 Apr 28. PMID 28452935, Free PMC Article
  4. Drosophila HNF4 regulates lipid mobilization and beta-oxidation. Palanker L, et al. Cell Metab, 2009 Mar. PMID 19254568, Free PMC Article
  5. Dynamics of nuclear matrix proteome during embryonic development in Drosophila melanogaster. Varma P, et al. J Biosci, 2011 Aug. PMID 21799256

See all (49) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables delta(3,5)-delta(2,4)-dienoyl-CoA isomerase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables isomerase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in fatty acid beta-oxidation NAS
Non-traceable Author Statement
more info
 PubMed 
Component Evidence Code Pubs
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in peroxisome ISM
Inferred from Sequence Model
more info
 PubMed 

General protein information

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Preferred Names
uncharacterized protein
Names
CG9577-PA
NP_608375.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    20166673..20168080
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_134531.4 → NP_608375.1  uncharacterized protein Dmel_CG9577 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_608375.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8SZ25, Q9W5W8
    Related
    FBpp0070006
    Conserved Domains (2) summary
    PRK05617
    Location:54 → 309
    PRK05617; 3-hydroxyisobutyryl-CoA hydrolase; Provisional
    cl23717
    Location:52 → 310
    crotonase-like; Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9W5W8 Q9W5W8

Gene LinkOut

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