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ndufab1b NADH:ubiquinone oxidoreductase subunit AB1b [ Danio rerio (zebrafish) ]

Gene ID: 325712, updated on 27-Mar-2024

Summary

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Official Symbol
ndufab1bprovided by ZNC
Official Full Name
NADH:ubiquinone oxidoreductase subunit AB1bprovided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-4437
See related
Ensembl:ENSDARG00000014915 AllianceGenome:ZFIN:ZDB-GENE-030131-4437
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
ndufab1; wu:fd05g01
Summary
Predicted to enable acyl binding activity and acyl carrier activity. Predicted to act upstream of or within fatty acid biosynthetic process. Predicted to be part of mitochondrial respiratory chain complex I. Predicted to be active in mitochondrion. Orthologous to human NDUFAB1 (NADH:ubiquinone oxidoreductase subunit AB1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

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Location:
chromosome: 3
Exon count:
5
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 3 NC_007114.7 (35535978..35541378, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 3 NC_007114.6 (35406470..35411870, complement)

Chromosome 3 - NC_007114.7Genomic Context describing neighboring genes Neighboring gene retinoblastoma binding protein 6 Neighboring gene trinucleotide repeat containing adaptor 6A Neighboring gene RNA pseudouridine synthase domain containing 1 Neighboring gene dynactin 5 Neighboring gene guanine nucleotide binding protein (G protein), gamma 13b

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Protein kinase C alpha and beta are positive regulators of thrombus formation in vivo in a zebrafish (Danio rerio) model of thrombosis. Williams CM, et al. J Thromb Haemost, 2011 Dec. PMID 21951302
  2. Molecular cloning and expression pattern of 11 genes involved in lipid metabolism in yellow catfish Pelteobagrus fulvidraco. Zheng JL, et al. Gene, 2013 Nov 15. PMID 23988502
  3. FusX: A Rapid One-Step Transcription Activator-Like Effector Assembly System for Genome Science. Ma AC, et al. Hum Gene Ther, 2016 Jun. PMID 26854857, Free PMC Article
  4. GLUT10 is required for the development of the cardiovascular system and the notochord and connects mitochondrial function to TGFβ signaling. Willaert A, et al. Hum Mol Genet, 2012 Mar 15. PMID 22116938, Free PMC Article
  5. Aclonifen causes developmental abnormalities in zebrafish embryos through mitochondrial dysfunction and oxidative stress. Lee JY, et al. Sci Total Environ, 2021 Jun 1. PMID 33548715

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables acyl binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables acyl carrier activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within fatty acid biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within fatty acid metabolic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within lipid metabolic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of mitochondrial respiratory chain complex I IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
NADH:ubiquinone oxidoreductase subunit AB1b
Names
NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1
NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1b

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001305569.1 → NP_001292498.1  NADH:ubiquinone oxidoreductase subunit AB1b

    See identical proteins and their annotated locations for NP_001292498.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate splice site in the 3' UTR compared to variant 1. Variants 1 and 2 encode the same protein.
    Source sequence(s)
    EH447216, EH519497, EH556548
    UniProtKB/TrEMBL
    A0A8M1P1B3, F1QCE9
    Related
    ENSDARP00000148152.1, ENSDART00000183075.1
    Conserved Domains (1) summary
    cl09936
    Location:29 → 149
    PP-binding; Phosphopantetheine attachment site

  2. NM_001305570.1 → NP_001292499.1  NADH:ubiquinone oxidoreductase subunit AB1b

    See identical proteins and their annotated locations for NP_001292499.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 encode the same protein.
    Source sequence(s)
    EH432779, EH519497, EH556548
    UniProtKB/TrEMBL
    A0A8M1P1B3, F1QCE9
    Related
    ENSDARP00000012558.6, ENSDART00000022147.8
    Conserved Domains (1) summary
    cl09936
    Location:29 → 149
    PP-binding; Phosphopantetheine attachment site

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007114.7 Reference GRCz11 Primary Assembly

    Range
    35535978..35541378 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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