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rpl27 ribosomal protein L27 [ Danio rerio (zebrafish) ]

Gene ID: 325618, updated on 27-Mar-2024

Summary

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Official Symbol
rpl27provided by ZNC
Official Full Name
ribosomal protein L27provided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-4343
See related
Ensembl:ENSDARG00000015128 AllianceGenome:ZFIN:ZDB-GENE-030131-4343
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
fc93a08; zgc:56171; wu:fc93a08
Summary
Predicted to be a structural constituent of ribosome. Acts upstream of or within erythrocyte differentiation. Predicted to be located in cytoplasmic side of rough endoplasmic reticulum membrane. Predicted to be part of cytosolic large ribosomal subunit. Is expressed in endodermal cell; intestine; liver; and pancreas. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia 16. Orthologous to human RPL27 (ribosomal protein L27). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 3
Exon count:
5
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 3 NC_007114.7 (29893966..29899226, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 3 NC_007114.6 (29763124..29768384, complement)

Chromosome 3 - NC_007114.7Genomic Context describing neighboring genes Neighboring gene ribosomal protein L3 Neighboring gene solute carrier family 25 member 39 Neighboring gene RUN domain containing 1 Neighboring gene granulin a antisense Neighboring gene granulin a

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Loss of function mutations in RPL27 and RPS27 identified by whole-exome sequencing in Diamond-Blackfan anaemia. Wang R, et al. Br J Haematol, 2015 Mar. PMID 25424902
  2. Systematic identification of seven ribosomal protein genes in bighead carp and their expression in response to microcystin-LR. Cai Y, et al. J Toxicol Sci, 2016 Apr. PMID 26961614
  3. Chemical and biological transfer: Which one is responsible for the maternal transfer toxicity of tris(1,3-dichloro-2-propyl) phosphate in zebrafish? Zhang Y, et al. Environ Pollut, 2018 Dec. PMID 30273864
  4. Multiple ribosomal proteins are expressed at high levels in developing zebrafish endoderm and are required for normal exocrine pancreas development. Provost E, et al. Zebrafish, 2013 Jun. PMID 23697888, Free PMC Article
  5. First profiling of lysine crotonylation of myofilament proteins and ribosomal proteins in zebrafish embryos. Kwon OK, et al. Sci Rep, 2018 Feb 26. PMID 29483630, Free PMC Article

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
  
enables structural constituent of ribosome IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within erythrocyte differentiation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within translation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytoplasmic side of rough endoplasmic reticulum membrane ISS
Inferred from Sequence or Structural Similarity
more info
  
part_of cytosolic large ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
  
part_of large ribosomal subunit ISS
Inferred from Sequence or Structural Similarity
more info
  
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
  
located_in ribosome IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
large ribosomal subunit protein eL27
Names
60S ribosomal protein L27
NP_956018.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_199724.1 → NP_956018.1  large ribosomal subunit protein eL27

    See identical proteins and their annotated locations for NP_956018.1

    Status: PROVISIONAL

    Source sequence(s)
    BC045965
    UniProtKB/Swiss-Prot
    Q7ZV82
    UniProtKB/TrEMBL
    B2GP62
    Related
    ENSDARP00000018737.6, ENSDART00000020311.7
    Conserved Domains (2) summary
    COG2163
    Location:1 → 127
    RPL14A; Ribosomal protein L14E/L6E/L27E [Translation, ribosomal structure and biogenesis]
    cl00354
    Location:1 → 136
    KOW; KOW: an acronym for the authors' surnames (Kyrpides, Ouzounis and Woese)

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007114.7 Reference GRCz11 Primary Assembly

    Range
    29893966..29899226 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q7ZV82.3 GenPept UniProtKB/Swiss-Prot:Q7ZV82

Gene LinkOut

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