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srpk1a SRSF protein kinase 1a [ Danio rerio (zebrafish) ]

Gene ID: 323679, updated on 27-Mar-2024

Summary

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Official Symbol
srpk1aprovided by ZNC
Official Full Name
SRSF protein kinase 1aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-2399
See related
Ensembl:ENSDARG00000073997 AllianceGenome:ZFIN:ZDB-GENE-030131-2399
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
srpk1; zgc:63789; wu:fc06h03
Summary
Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in intracellular signal transduction; regulation of mRNA processing; and spliceosomal complex assembly. Predicted to act upstream of or within protein phosphorylation. Predicted to be active in cytoplasm and nucleus. Orthologous to human SRPK1 (SRSF protein kinase 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 8
Exon count:
17
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 8 NC_007119.7 (23861420..23879625)
105 previous assembly GRCz10 (GCF_000002035.5) 8 NC_007119.6 (23840186..23858160)

Chromosome 8 - NC_007119.7Genomic Context describing neighboring genes Neighboring gene basal body orientation factor 1a Neighboring gene mitogen-activated protein kinase 14a Neighboring gene LHFPL tetraspan subfamily member 5b Neighboring gene copine Va

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  3. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
  
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein serine/threonine kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in intracellular signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in peptidyl-serine phosphorylation IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within phosphorylation IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of mRNA processing IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in spliceosomal complex assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
SRSF protein kinase 1; SRSF protein kinase 1a
Names
serine/arginine-rich protein specific kinase 1
serine/arginine-rich protein specific kinase 1a
NP_955944.1
XP_017212769.2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_199650.1 → NP_955944.1  SRSF protein kinase 1a

    See identical proteins and their annotated locations for NP_955944.1

    Status: PROVISIONAL

    Source sequence(s)
    BC056825
    UniProtKB/TrEMBL
    Q6PGU8
    Related
    ENSDARP00000032398.6, ENSDART00000037109.7
    Conserved Domains (2) summary
    smart00220
    Location:82 → 224
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cl21453
    Location:72 → 632
    PKc_like; Protein Kinases, catalytic domain

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007119.7 Reference GRCz11 Primary Assembly

    Range
    23861420..23879625
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017357280.2 → XP_017212769.2  SRSF protein kinase 1 isoform X1

    UniProtKB/TrEMBL
    A0A8M6YZP6
    Conserved Domains (1) summary
    cl21453
    Location:72 → 632
    PKc_like; Protein Kinases, catalytic domain

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394724.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    115326..138029
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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