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CG12096 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 32269, updated on 5-May-2024

Summary

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Official Symbol
CG12096provided by FlyBase
Primary source
FLYBASE:FBgn0030457
Locus tag
Dmel_CG12096
See related
AllianceGenome:FB:FBgn0030457
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
12096; Dmel\CG12096; dS5b; S5b; S5b/PSMD5
Summary
Predicted to be involved in proteasome assembly. Is expressed in adult head and organism. Orthologous to human PSMD5 (proteasome 26S subunit, non-ATPase 5). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
11E1-11E1; 1-42 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (13159604..13162854)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (13053637..13056887)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Brahma associated protein 60kD Neighboring gene Leucine-rich repeat-containing G protein-coupled receptor 4 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Role of S5b/PSMD5 in proteasome inhibition caused by TNF-α/NFκB in higher eukaryotes. Shim SM, et al. Cell Rep, 2012 Sep 27. PMID 22921402
  2. Drosophila BAP60 is an essential component of the Brahma complex, required for gene activation and repression. Möller A, et al. J Mol Biol, 2005 Sep 16. PMID 16083904
  3. Proteasome regulation by ADP-ribosylation. Cho-Park PF, et al. Cell, 2013 Apr 25. PMID 23622245, Free PMC Article
  4. The BEAF insulator regulates genes involved in cell polarity and neoplastic growth. Gurudatta BV, et al. Dev Biol, 2012 Sep 1. PMID 22743648, Free PMC Article
  5. A network of conserved damage survival pathways revealed by a genomic RNAi screen. Ravi D, et al. PLoS Genet, 2009 Jun. PMID 19543366, Free PMC Article

See all (28) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Process Evidence Code Pubs
involved_in proteasome assembly IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG12096-PA
CG12096-PB
CG12096-PC

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    13159604..13162854
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_132634.4 → NP_572862.2  uncharacterized protein Dmel_CG12096, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_572862.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A9UNC9, Q7K0M3, Q8SZZ0, Q9VYG1
    UniProtKB/TrEMBL
    X2JBJ9
    Related
    FBpp0073558
    Conserved Domains (1) summary
    pfam10508
    Location:4 → 502
    Proteasom_PSMB; Proteasome non-ATPase 26S subunit

  2. NM_001298262.1 → NP_001285191.1  uncharacterized protein Dmel_CG12096, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001285191.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A9UNC9, Q7K0M3, Q8SZZ0, Q9VYG1
    UniProtKB/TrEMBL
    X2JBJ9
    Conserved Domains (1) summary
    pfam10508
    Location:4 → 502
    Proteasom_PSMB; Proteasome non-ATPase 26S subunit

  3. NM_001298261.1 → NP_001285190.1  uncharacterized protein Dmel_CG12096, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001285190.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A9UNC9, Q7K0M3, Q8SZZ0, Q9VYG1
    UniProtKB/TrEMBL
    X2JBJ9
    Conserved Domains (1) summary
    pfam10508
    Location:4 → 502
    Proteasom_PSMB; Proteasome non-ATPase 26S subunit
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VYG1.3 Q9VYG1
X2JBJ9 X2JBJ9

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