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csnk1da casein kinase 1, delta a [ Danio rerio (zebrafish) ]

Gene ID: 322106, updated on 27-Mar-2024

Summary

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Official Symbol
csnk1daprovided by ZNC
Official Full Name
casein kinase 1, delta aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-825
See related
Ensembl:ENSDARG00000008370 AllianceGenome:ZFIN:ZDB-GENE-030131-825
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
Csnk1d; csnk1dl; zgc:63971; wu:fb50c04
Summary
Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in several processes, including organelle assembly; positive regulation of canonical Wnt signaling pathway; and positive regulation of proteasomal ubiquitin-dependent protein catabolic process. Predicted to act upstream of or within Wnt signaling pathway and protein phosphorylation. Predicted to be active in cytoplasm; nucleus; and spindle microtubule. Is expressed in several structures, including brain; head; pectoral fin; post-vent region; and tail bud. Human ortholog(s) of this gene implicated in advanced sleep phase syndrome 2. Orthologous to human CSNK1D (casein kinase 1 delta). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

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Location:
chromosome: 3
Exon count:
10
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 3 NC_007114.7 (36173203..36210387, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 3 NC_007114.6 (36043605..36080789, complement)

Chromosome 3 - NC_007114.7Genomic Context describing neighboring genes Neighboring gene endo-beta-N-acetylglucosaminidase Neighboring gene solute carrier family 16 member 3a Neighboring gene dihydrouridine synthase 1-like (S. cerevisiae) Neighboring gene G protein pathway suppressor 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Casein kinase 1δ activity: a key element in the zebrafish circadian timing system. Smadja Storz S, et al. PLoS One, 2013. PMID 23349822, Free PMC Article
  2. The CK1 gene family: expression patterning in zebrafish development. Albornoz A, et al. Biol Res, 2007. PMID 18064361
  3. The circadian clock of teleost fish: a comparative analysis reveals distinct fates for duplicated genes. Toloza-Villalobos J, et al. J Mol Evol, 2015 Jan. PMID 25487517
  4. Evolutionary emergence of the rac3b/rfng/sgca regulatory cluster refined mechanisms for hindbrain boundaries formation. Letelier J, et al. Proc Natl Acad Sci U S A, 2018 Apr 17. PMID 29610331, Free PMC Article
  5. Evolution of gene function and regulatory control after whole-genome duplication: comparative analyses in vertebrates. Kassahn KS, et al. Genome Res, 2009 Aug. PMID 19439512, Free PMC Article

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Data indicate that CK1delta inhibition abolishes rhythmic pineal aanat2 mRNA expression.
    Title: Casein kinase 1δ activity: a key element in the zebrafish circadian timing system.
Submit: New GeneRIF Correction

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
  
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein serine kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein serine/threonine kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
  
involved_in endocytosis IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in peptidyl-serine phosphorylation IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within phosphorylation IEA
Inferred from Electronic Annotation
more info
  
involved_in positive regulation of canonical Wnt signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in positive regulation of proteasomal ubiquitin-dependent protein catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
casein kinase I isoform delta-A; casein kinase I
Names
CKI-delta-A
CKId-A
casein kinase 1, delta like
NP_955877.1
XP_005164045.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_199583.1 → NP_955877.1  casein kinase I isoform delta-A

    See identical proteins and their annotated locations for NP_955877.1

    Status: PROVISIONAL

    Source sequence(s)
    BC054583
    UniProtKB/Swiss-Prot
    Q7T2E3
    Related
    ENSDARP00000003101.6, ENSDART00000025326.7
    Conserved Domains (2) summary
    COG0515
    Location:9 → 380
    SPS1; Serine/threonine protein kinase [Signal transduction mechanisms]
    cd14125
    Location:8 → 282
    STKc_CK1_delta_epsilon; Catalytic domain of the Serine/Threonine protein kinases, Casein Kinase 1 delta and epsilon

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007114.7 Reference GRCz11 Primary Assembly

    Range
    36173203..36210387 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005163988.4 → XP_005164045.1  casein kinase I isoform X1

    UniProtKB/TrEMBL
    A0A286YAS3, A0A8M2BBB2
    Related
    ENSDARP00000144306.1, ENSDART00000175208.2
    Conserved Domains (2) summary
    COG0515
    Location:9 → 380
    SPS1; Serine/threonine protein kinase [Signal transduction mechanisms]
    cd14125
    Location:8 → 282
    STKc_CK1_delta_epsilon; Catalytic domain of the Serine/Threonine protein kinases, Casein Kinase 1 delta and epsilon
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q7T2E3.1 GenPept UniProtKB/Swiss-Prot:Q7T2E3

Gene LinkOut

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