ndufa10 NADH:ubiquinone oxidoreductase subunit A10 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: ndufa10provided by ZNC
Official Full Name: NADH:ubiquinone oxidoreductase subunit A10provided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-670
See related: Ensembl:ENSDARG00000013333 AllianceGenome:ZFIN:ZDB-GENE-030131-670
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:73344; wu:fb39a11
Summary: Predicted to be involved in mitochondrial electron transport, NADH to ubiquinone. Predicted to be located in mitochondrial matrix and respirasome. Predicted to be part of mitochondrial respiratory chain complex I. Predicted to be active in cytoplasm. Is expressed in several structures, including alar plate midbrain region; gut; immature eye; myotome; and nervous system. Human ortholog(s) of this gene implicated in nuclear type mitochondrial complex I deficiency 22. Orthologous to human NDUFA10 (NADH:ubiquinone oxidoreductase subunit A10). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 9

Exon count:: 10

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	9	NC_007120.7 (23740506..23747231, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	9	NC_007120.6 (23929637..23936362, complement)

Chromosome 9 - NC_007120.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

fb39a11 (e-PCR)
- UniSTS:187172

AI384190 (e-PCR)
- UniSTS:206742

fb39a11.x1 (e-PCR)
- UniSTS:203185

Gene Ontology Provided by ZFIN

Process	Evidence Code	Pubs
involved_in mitochondrial electron transport, NADH to ubiquinone	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within mitochondrial electron transport, NADH to ubiquinone	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in mitochondrial matrix	IEA Inferred from Electronic Annotation more info
part_of mitochondrial respiratory chain complex I	IBA Inferred from Biological aspect of Ancestor more info
part_of mitochondrial respiratory chain complex I	IEA Inferred from Electronic Annotation more info
located_in mitochondrion	IEA Inferred from Electronic Annotation more info
located_in respirasome	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial

Names: NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10

NP_955872.1

EC 1.6.99.3

EC 7.1.1.2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_199578.1 → NP_955872.1 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial

See identical proteins and their annotated locations for NP_955872.1

Status: PROVISIONAL

Source sequence(s)

BC059660

UniProtKB/TrEMBL

Q6PBM0

Related

ENSDARP00000004708.5, ENSDART00000010311.8

Conserved Domains (1) summary

cd02030
Location:59 → 277

NDUO42; NADH:Ubiquinone oxioreductase, 42 kDa (NDUO42) is a family of proteins that are highly similar to deoxyribonucleoside kinases (dNK). Members of this family have been identified as one of the subunits of NADH:Ubiquinone oxioreductase (complex I), a ...