zfr zinc finger RNA binding protein [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: zfrprovided by ZNC
Official Full Name: zinc finger RNA binding proteinprovided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-378
See related: Ensembl:ENSDARG00000027109 AllianceGenome:ZFIN:ZDB-GENE-030131-378
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: hnrpa1; zgc:66235; zgc:66403; wu:fb25b08
Summary: Predicted to enable double-stranded RNA binding activity and single-stranded RNA binding activity. Predicted to be located in cytoplasm and nucleus. Orthologous to human ZFR (zinc finger RNA binding protein). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: chromosome: 5

Exon count:: 20

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	5	NC_007116.7 (41124736..41142834, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	5	NC_007116.6 (40524583..40542671, complement)

Chromosome 5 - NC_007116.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help

See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

In D. rerio, Zfr mRNA expression was highest in unfertilized eggs and declines throughout development.
Title: Early developmental expression of Mus musculus zinc finger RNA-binding protein compared to orthologs in Caenorhabditis elegans and Danio rerio and subcellular localization of Mus musculus and Caenorhabditis elegans zinc finger RNA-binding protein in 2-cell Mus musculus embryos.

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Markers

AI397026 (e-PCR)
- UniSTS:206681

fb25b08.y1 (e-PCR)
- UniSTS:190350

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables DNA binding	IEA Inferred from Electronic Annotation more info
enables RNA binding	IEA Inferred from Electronic Annotation more info
enables double-stranded RNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables nucleic acid binding	IEA Inferred from Electronic Annotation more info
enables single-stranded RNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables zinc ion binding	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

Go to the top of the page Help

Preferred Names: zinc finger RNA-binding protein

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_199558.2 → NP_955852.2 zinc finger RNA-binding protein

Status: VALIDATED

Source sequence(s)

BX470118

UniProtKB/Swiss-Prot

Q6PCR6

UniProtKB/TrEMBL

A0A8M1PD13, A2BGG2

Related

ENSDARP00000069275.4, ENSDART00000074789.6

Conserved Domains (3) summary

smart00572
Location:784 → 1037

DZF; domain in DSRM or ZnF_C2H2 domain containing proteins

smart00451
Location:575 → 606

ZnF_U1; U1-like zinc finger

sd00020
Location:578 → 600

ZF_C2H2; C2H2 Zn finger [structural motif]