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Ankar ankyrin and armadillo repeat containing [ Mus musculus (house mouse) ]

Gene ID: 319695, updated on 5-Mar-2024

Summary

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Official Symbol
Ankarprovided by MGI
Official Full Name
ankyrin and armadillo repeat containingprovided by MGI
Primary source
MGI:MGI:2442559
See related
Ensembl:ENSMUSG00000039342 AllianceGenome:MGI:2442559
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
4932422E22Rik
Summary
Predicted to be located in membrane. Predicted to be integral component of membrane. Orthologous to human ANKAR (ankyrin and armadillo repeat containing). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Restricted expression toward testis adult (RPKM 7.7) See more
Orthologs
human all
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Genomic context

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Location:
1 C3; 1 36.8 cM
Exon count:
24
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (72682139..72739743, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (72642980..72700584, complement)

Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene membrane associated ring-CH-type finger 4 Neighboring gene SWI/SNF related matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 Neighboring gene STARR-positive B cell enhancer ABC_E1548 Neighboring gene STARR-seq mESC enhancer starr_01281 Neighboring gene predicted gene, 39662 Neighboring gene STARR-seq mESC enhancer starr_01283 Neighboring gene ribosomal protein L19 pseudogene Neighboring gene ribosomal protein L37a Neighboring gene predicted gene, 51632 Neighboring gene predicted gene, 39663

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Characterization of a novel human gene containing ANK repeats and ARM domains. Occhi G, et al. Biochem Biophys Res Commun, 2004 May 21. PMID 15110750
  2. A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. Yokoyama S, et al. Dev Cell, 2009 Dec. PMID 20059953, Free PMC Article
  3. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
  4. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
  5. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
ankyrin and armadillo repeat-containing protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001347063.1 → NP_001333992.1  ankyrin and armadillo repeat-containing protein isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC121498, AC163484
    Consensus CDS
    CCDS83554.1
    UniProtKB/TrEMBL
    A0A1D5RM61, B7ZNI2
    Related
    ENSMUSP00000148801.2, ENSMUST00000211837.2

  2. NM_176980.4 → NP_795954.2  ankyrin and armadillo repeat-containing protein isoform 1

    See identical proteins and their annotated locations for NP_795954.2

    Status: VALIDATED

    Source sequence(s)
    AK030065, AK077036, BC132415
    Consensus CDS
    CCDS15035.1
    UniProtKB/Swiss-Prot
    A2RT91, Q8C0Q1
    UniProtKB/TrEMBL
    A0A1D5RM61
    Related
    ENSMUSP00000054056.5, ENSMUST00000053499.6
    Conserved Domains (5) summary
    cd00020
    Location:751 → 864
    ARM; Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin, ...
    cd00204
    Location:581 → 705
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam12796
    Location:587 → 682
    Ank_2; Ankyrin repeats (3 copies)
    sd00045
    Location:582 → 613
    ANK; ANK repeat [structural motif]
    sd00043
    Location:750 → 782
    ARM; armadillo repeat [structural motif]

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000067.7 Reference GRCm39 C57BL/6J

    Range
    72682139..72739743 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006496060.3 → XP_006496123.1  ankyrin and armadillo repeat-containing protein isoform X1

    UniProtKB/TrEMBL
    A0A1D5RM61
    Conserved Domains (6) summary
    PLN03200
    Location:705 → 973
    PLN03200; cellulose synthase-interactive protein; Provisional
    COG5064
    Location:870 → 1116
    SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
    sd00045
    Location:602 → 636
    ANK; ANK repeat [structural motif]
    sd00043
    Location:737 → 769
    ARM; armadillo repeat [structural motif]
    pfam12796
    Location:574 → 669
    Ank_2; Ankyrin repeats (3 copies)
    cl39094
    Location:526 → 599
    Ank_2; Ankyrin repeats (3 copies)

  2. XM_017321180.2 → XP_017176669.1  ankyrin and armadillo repeat-containing protein isoform X2

    Conserved Domains (5) summary
    PLN03200
    Location:223 → 491
    PLN03200; cellulose synthase-interactive protein; Provisional
    COG5064
    Location:388 → 634
    SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
    sd00045
    Location:87 → 118
    ANK; ANK repeat [structural motif]
    sd00043
    Location:255 → 287
    ARM; armadillo repeat [structural motif]
    pfam12796
    Location:92 → 187
    Ank_2; Ankyrin repeats (3 copies)

RNA

  1. XR_003955720.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A2RT91.1 GenPept UniProtKB/Swiss-Prot:A2RT91

Gene LinkOut

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