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P2ry10 P2Y receptor family member 10 [ Rattus norvegicus (Norway rat) ]

Gene ID: 317219, updated on 11-Apr-2024

Summary

Official Symbol
P2ry10provided by RGD
Official Full Name
P2Y receptor family member 10provided by RGD
Primary source
RGD:1561912
See related
Ensembl:ENSRNOG00000037839 AllianceGenome:RGD:1561912
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1561912
Summary
Predicted to enable G protein-coupled receptor activity. Predicted to be involved in positive regulation of Rho protein signal transduction and positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway. Predicted to be integral component of plasma membrane. Orthologous to human P2RY10 (P2Y receptor family member 10). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Thymus (RPKM 331.0), Spleen (RPKM 175.8) and 1 other tissue See more
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Genomic context

Location:
Xq22
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) X NC_086039.1 (76184064..76279996)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) X NC_051356.1 (72121558..72207174)
106 previous assembly Rnor_6.0 (GCF_000001895.5) X NC_005120.4 (78158729..78210413)

Chromosome X - NC_086039.1Genomic Context describing neighboring genes Neighboring gene U6 spliceosomal RNA Neighboring gene lysophosphatidic acid receptor 4 Neighboring gene U6 spliceosomal RNA Neighboring gene P2Y receptor family member 10B Neighboring gene prohibitin 1, pseudogene 3

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Pathways from PubChem

General gene information

Clone Names

  • MGC189289

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables G protein-coupled receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 
involved_in phospholipase C-activating G protein-coupled receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in positive regulation of Rho protein signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
putative P2Y purinoceptor 10
Names
purinergic receptor P2Y, G-protein coupled, 10
purinergic receptor P2Y10

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001177682.1NP_001171153.1  putative P2Y purinoceptor 10

    See identical proteins and their annotated locations for NP_001171153.1

    Status: PROVISIONAL

    Source sequence(s)
    BC168967
    UniProtKB/TrEMBL
    A6IV61, B5DF87
    Related
    ENSRNOP00000046594.3, ENSRNOT00000048695.6
    Conserved Domains (2) summary
    cd14964
    Location:2350
    7tm_GPCRs; TM helix 1 [structural motif]
    cl28897
    Location:23305
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086039.1 Reference GRCr8

    Range
    76184064..76279996
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063280020.1XP_063136090.1  putative P2Y purinoceptor 10 isoform X1

  2. XM_039099736.2XP_038955664.1  putative P2Y purinoceptor 10 isoform X2

    UniProtKB/TrEMBL
    A6IV61, B5DF87
    Related
    ENSRNOP00000092809.1
    Conserved Domains (2) summary
    cd14964
    Location:2350
    7tm_GPCRs; TM helix 1 [structural motif]
    cl28897
    Location:23305
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
  3. XM_063280021.1XP_063136091.1  putative P2Y purinoceptor 10 isoform X2

    UniProtKB/TrEMBL
    B5DF87
  4. XM_039099737.2XP_038955665.1  putative P2Y purinoceptor 10 isoform X2

    UniProtKB/TrEMBL
    A6IV61, B5DF87
    Conserved Domains (2) summary
    cd14964
    Location:2350
    7tm_GPCRs; TM helix 1 [structural motif]
    cl28897
    Location:23305
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily