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Rrh retinal pigment epithelium derived rhodopsin homolog [ Rattus norvegicus (Norway rat) ]

Gene ID: 310869, updated on 13-Apr-2024

Summary

Official Symbol
Rrhprovided by RGD
Official Full Name
retinal pigment epithelium derived rhodopsin homologprovided by RGD
Primary source
RGD:1308948
See related
Ensembl:ENSRNOG00000053349 AllianceGenome:RGD:1308948
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable G protein-coupled photoreceptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway; cellular response to light stimulus; and phototransduction. Predicted to be active in photoreceptor outer segment. Predicted to be integral component of plasma membrane. Orthologous to human RRH (retinal pigment epithelium-derived rhodopsin homolog). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Spleen (RPKM 5.7), Brain (RPKM 4.6) and 9 other tissues See more
Orthologs
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Genomic context

Location:
2q43
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (221036436..221048627, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (218362195..218374387, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (235237422..235250474, complement)

Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene epidermal growth factor Neighboring gene leucine-rich repeat, Ig-like and transmembrane domains 3 Neighboring gene uncharacterized LOC134485966 Neighboring gene GAR1 ribonucleoprotein

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Pathways from PubChem

General gene information

Markers

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables G protein-coupled photoreceptor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in cellular response to light stimulus IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in detection of visible light IEA
Inferred from Electronic Annotation
more info
 
involved_in phototransduction IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in visual perception IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in photoreceptor outer segment IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
visual pigment-like receptor peropsin

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001107726.2NP_001101196.1  visual pigment-like receptor peropsin isoform 2

    See identical proteins and their annotated locations for NP_001101196.1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000002
    UniProtKB/TrEMBL
    A6HVP7, A6HVP8, D3ZY73
    Related
    ENSRNOP00000072493.1, ENSRNOT00000085096.2
    Conserved Domains (1) summary
    pfam00001
    Location:47197
    7tm_1; 7 transmembrane receptor (rhodopsin family)
  2. NM_001415060.1NP_001401989.1  visual pigment-like receptor peropsin isoform 1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000002
    UniProtKB/TrEMBL
    A0A1W2Q6H2
    Related
    ENSRNOP00000076275.1, ENSRNOT00000093631.2

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086020.1 Reference GRCr8

    Range
    221036436..221048627 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)