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Gpr45 G protein-coupled receptor 45 [ Rattus norvegicus (Norway rat) ]

Gene ID: 301372, updated on 5-Mar-2024

Summary

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Official Symbol
Gpr45provided by RGD
Official Full Name
G protein-coupled receptor 45provided by RGD
Primary source
RGD:1306253
See related
Ensembl:ENSRNOG00000016446 AllianceGenome:RGD:1306253
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be integral component of membrane. Orthologous to human GPR45 (G protein-coupled receptor 45). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
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Genomic context

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Location:
9q22
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 9 NC_086027.1 (52713825..52801826)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 9 NC_051344.1 (45221364..45309713)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 9 NC_005108.4 (49837868..49841337)

Chromosome 9 - NC_086027.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC103690528 Neighboring gene small nucleolar RNA SNORA17 Neighboring gene mitochondrial ribosomal protein S9 Neighboring gene heterogeneous nuclear ribonucleoprotein A1, pseudogene 34 Neighboring gene actin related protein 2/3 complex, subunit 5-like, pseudogene 1 Neighboring gene transforming growth factor, beta receptor associated protein 1 Neighboring gene similar to human chromosome 2 open reading frame 49

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables G protein-coupled receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
probable G-protein coupled receptor 45

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001106906.1 → NP_001100376.1  probable G-protein coupled receptor 45

    See identical proteins and their annotated locations for NP_001100376.1

    Status: PROVISIONAL

    Source sequence(s)
    CH473965
    UniProtKB/TrEMBL
    A6INQ8, D4A8X5
    Related
    ENSRNOP00000021999.3, ENSRNOT00000021999.5
    Conserved Domains (2) summary
    cd14964
    Location:36 → 62
    7tm_GPCRs; TM helix 1 [structural motif]
    cl28897
    Location:35 → 336
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086027.1 Reference GRCr8

    Range
    52713825..52801826
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039083259.2 → XP_038939187.1  probable G-protein coupled receptor 45 isoform X1

    UniProtKB/TrEMBL
    A6INQ8, D4A8X5
    Conserved Domains (2) summary
    cd14964
    Location:36 → 62
    7tm_GPCRs; TM helix 1 [structural motif]
    cl28897
    Location:35 → 336
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

RNA

  1. XR_005488869.2 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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Chemical Information
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