U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Ndufa11 NADH:ubiquinone oxidoreductase subunit A11 [ Rattus norvegicus (Norway rat) ]

Gene ID: 301123, updated on 5-Mar-2024

Summary

Official Symbol
Ndufa11provided by RGD
Official Full Name
NADH:ubiquinone oxidoreductase subunit A11provided by RGD
Primary source
RGD:1303292
See related
Ensembl:ENSRNOG00000048320 AllianceGenome:RGD:1303292
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to be involved in mitochondrial respiratory chain complex I assembly. Predicted to be located in mitochondrion. Predicted to be part of mitochondrial respiratory chain complex I. Human ortholog(s) of this gene implicated in nuclear type mitochondrial complex I deficiency 14. Orthologous to human NDUFA11 (NADH:ubiquinone oxidoreductase subunit A11). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Heart (RPKM 2764.8), Muscle (RPKM 1817.2) and 9 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Location:
9q11
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 9 NC_086027.1 (1637614..1641673)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 9 NC_051344.1 (1550487..1554546)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 9 NC_005108.4 (10334104..10338163, complement)

Chromosome 9 - NC_086027.1Genomic Context describing neighboring genes Neighboring gene RAN binding protein 3 Neighboring gene calcyphosine Neighboring gene vimentin-type intermediate filament associated coiled-coil protein Neighboring gene fucosyltransferase 4, pseudogene 1 Neighboring gene neurturin

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in mitochondrial respiratory chain complex I assembly IEA
Inferred from Electronic Annotation
more info
 
involved_in mitochondrial respiratory chain complex I assembly ISO
Inferred from Sequence Orthology
more info
 
involved_in mitochondrial respiratory chain complex I assembly ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
located_in mitochondrial inner membrane ISO
Inferred from Sequence Orthology
more info
 
part_of mitochondrial respiratory chain complex I IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of mitochondrial respiratory chain complex I IEA
Inferred from Electronic Annotation
more info
 
part_of mitochondrial respiratory chain complex I ISO
Inferred from Sequence Orthology
more info
 
part_of mitochondrial respiratory chain complex I ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info
 
located_in mitochondrion ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11
Names
CI-B14.7
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 11
NADH-ubiquinone oxidoreductase subunit B14.7
complex I-B14.7
NP_997682.1

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_212517.1NP_997682.1  NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11

    See identical proteins and their annotated locations for NP_997682.1

    Status: PROVISIONAL

    Source sequence(s)
    AY272059
    UniProtKB/Swiss-Prot
    Q80W89
    UniProtKB/TrEMBL
    A0A8L2QX46, A6KQV2
    Related
    ENSRNOP00000064246.2, ENSRNOT00000070862.3
    Conserved Domains (1) summary
    pfam02466
    Location:27125
    Tim17; Tim17/Tim22/Tim23/Pmp24 family

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086027.1 Reference GRCr8

    Range
    1637614..1641673
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)