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Ndufa7 NADH:ubiquinone oxidoreductase subunit A7 [ Rattus norvegicus (Norway rat) ]

Gene ID: 299643, updated on 5-Mar-2024

Summary

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Official Symbol
Ndufa7provided by RGD
Official Full Name
NADH:ubiquinone oxidoreductase subunit A7provided by RGD
Primary source
RGD:1304597
See related
Ensembl:ENSRNOG00000006901 AllianceGenome:RGD:1304597
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to be involved in mitochondrial electron transport, NADH to ubiquinone. Predicted to be located in mitochondrion. Predicted to be part of mitochondrial respiratory chain complex I. Orthologous to human NDUFA7 (NADH:ubiquinone oxidoreductase subunit A7). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Heart (RPKM 1795.0), Muscle (RPKM 1080.2) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Ndufa7 in Genome Data Viewer
Location:
7q13
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (15311446..15324226)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (14609283..14622064)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (18683553..18696332)

Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene KN motif and ankyrin repeat domains 3 Neighboring gene ribosomal protein S28 Neighboring gene CD320 molecule Neighboring gene vomeronasal type-2 receptor 116-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Accessory subunits are integral for assembly and function of human mitochondrial complex I. Stroud DA, et al. Nature, 2016 Oct 6. PMID 27626371
  2. The subunit composition of the human NADH dehydrogenase obtained by rapid one-step immunopurification. Murray J, et al. J Biol Chem, 2003 Apr 18. PMID 12611891
  3. Architecture of Human Mitochondrial Respiratory Megacomplex I(2)III(2)IV(2). Guo R, et al. Cell, 2017 Sep 7. PMID 28844695
  4. Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria. Mootha VK, et al. Cell, 2003 Nov 26. PMID 14651853
  5. A mitochondrial protein compendium elucidates complex I disease biology. Pagliarini DJ, et al. Cell, 2008 Jul 11. PMID 18614015, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Clone Names

  • MGC188160

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
involved_in mitochondrial electron transport, NADH to ubiquinone IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in mitochondrial inner membrane ISO
Inferred from Sequence Orthology
more info
  
part_of mitochondrial respiratory chain complex I IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of mitochondrial respiratory chain complex I ISO
Inferred from Sequence Orthology
more info
  
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7
Names
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7 (B14.5a)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001106772.2 → NP_001100242.2  NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7

    See identical proteins and their annotated locations for NP_001100242.2

    Status: PROVISIONAL

    Source sequence(s)
    BC157817
    UniProtKB/TrEMBL
    A9UMV9, F7FE81
    Related
    ENSRNOP00000009425.4, ENSRNOT00000009425.8
    Conserved Domains (1) summary
    pfam07347
    Location:5 → 99
    CI-B14_5a; NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a)

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086025.1 Reference GRCr8

    Range
    15311446..15324226
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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