Atp6v0b ATPase H+ transporting V0 subunit B [Rattus norvegicus (Norway rat)] - Gene

Summary

Symbol: Atp6v0bprovided by RGD
Full Name: ATPase H+ transporting V0 subunit Bprovided by RGD
Primary source: RGD:1308303
See related: AllianceGenome:RGD:1308303
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Atp6v0bl1
Summary: Predicted to enable proton transmembrane transporter activity. Predicted to be involved in proton transmembrane transport. Predicted to be located in endosome. Predicted to be integral component of membrane. Predicted to be part of proton-transporting V-type ATPase, V0 domain. Orthologous to human ATP6V0B (ATPase H+ transporting V0 subunit b). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in Brain (RPKM 589.0), Kidney (RPKM 407.8) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 5q36

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	5	NC_086023.1 (136708823..136710339, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	5	NC_051340.1 (131423384..131424900, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	5	NC_005104.4 (136718352..136719868, complement)

Chromosome 5 - NC_086023.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

UniSTS:224283 (e-PCR)
- UniSTS:224283

RH131406 (e-PCR)
- UniSTS:214689

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables proton-transporting ATPase activity, rotational mechanism	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in proton transmembrane transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in clathrin-coated vesicle membrane	IEA Inferred from Electronic Annotation more info
located_in endosome	ISO Inferred from Sequence Orthology more info
located_in membrane	ISO Inferred from Sequence Orthology more info
part_of proton-transporting V-type ATPase complex	ISO Inferred from Sequence Orthology more info
part_of proton-transporting V-type ATPase, V0 domain	IEA Inferred from Electronic Annotation more info
part_of transmembrane transporter complex	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: V-type proton ATPase 21 kDa proteolipid subunit c''

Names: ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b; ATPase, H+ transporting, lysosomal V0 subunit B; ATPase, H+ transporting, lysosomal V0 subunit B-like 1; V-type proton ATPase 21 kDa proteolipid subunit

NP_001100151.1

EC 7.1.2.2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001106681.1 → NP_001100151.1 V-type proton ATPase 21 kDa proteolipid subunit c''

See identical proteins and their annotated locations for NP_001100151.1

Status: PROVISIONAL

Source sequence(s)

CH474008

UniProtKB/TrEMBL

A6JZF2

Conserved Domains (1) summary

pfam00137
Location:31 → 91

ATP-synt_C; ATP synthase subunit C