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Gpat2 glycerol-3-phosphate acyltransferase 2, mitochondrial [ Rattus norvegicus (Norway rat) ]

Gene ID: 296130, updated on 4-Jan-2025

Summary

Official Symbol
Gpat2provided by RGD
Official Full Name
glycerol-3-phosphate acyltransferase 2, mitochondrialprovided by RGD
Primary source
RGD:1304904
See related
EnsemblRapid:ENSRNOG00000013906 AllianceGenome:RGD:1304904
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1304904
Summary
Predicted to enable 1-acylglycerol-3-phosphate O-acyltransferase activity and glycerol-3-phosphate O-acyltransferase activity. Predicted to be involved in phosphatidic acid biosynthetic process; piRNA processing; and triglyceride biosynthetic process. Predicted to act upstream of or within glycerol-3-phosphate metabolic process. Located in mitochondrial outer membrane. Orthologous to human GPAT2 (glycerol-3-phosphate acyltransferase 2, mitochondrial). [provided by Alliance of Genome Resources, Jan 2025]
Expression
Biased expression in Testes (RPKM 38.4), Kidney (RPKM 9.8) and 8 other tissues See more
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Genomic context

See Gpat2 in Genome Data Viewer
Location:
3q36
Exon count:
21
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (135099751..135110355)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (114646446..114657051)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (119949921..120003090)

Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene astacin like metalloendopeptidase Neighboring gene adrenoceptor alpha 2B Neighboring gene fumarylacetoacetate hydrolase domain containing 2A Neighboring gene ribosomal protein L9, pseudogene 28

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Pathways from PubChem

General gene information

Gene Ontology Provided by RGD

Component Evidence Code Pubs
located_in membrane  
located_in mitochondrial outer membrane PubMed 
is_active_in mitochondrion  
located_in mitochondrion  

General protein information

Preferred Names
glycerol-3-phosphate acyltransferase 2, mitochondrial
Names
1-acylglycerol-3-phosphate O-acyltransferase GPAT2
NP_001162001.1
XP_017447069.1
XP_038960496.1
XP_038960497.1
XP_063139400.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001168529.1NP_001162001.1  glycerol-3-phosphate acyltransferase 2, mitochondrial

    See identical proteins and their annotated locations for NP_001162001.1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000003
    UniProtKB/Swiss-Prot
    D3ZI76
    UniProtKB/TrEMBL
    A0A8I5ZY97
    Related
    ENSRNOP00000106144.1, ENSRNOT00000155900.1
    Conserved Domains (1) summary
    cd07993
    Location:176387
    LPLAT_DHAPAT-like; Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: GPAT-like

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086021.1 Reference GRCr8

    Range
    135099751..135110355
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017591580.2XP_017447069.1  glycerol-3-phosphate acyltransferase 2, mitochondrial isoform X1

    UniProtKB/TrEMBL
    A0A8I5ZY97
    Conserved Domains (1) summary
    cd07993
    Location:176387
    LPLAT_DHAPAT-like; Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: GPAT-like
  2. XM_039104569.1XP_038960497.1  glycerol-3-phosphate acyltransferase 2, mitochondrial isoform X3

    UniProtKB/Swiss-Prot
    D3ZI76
    UniProtKB/TrEMBL
    A0A8I5ZY97
    Related
    ENSRNOP00000018677.6, ENSRNOT00000018677.8
    Conserved Domains (1) summary
    cd07993
    Location:176387
    LPLAT_DHAPAT-like; Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: GPAT-like
  3. XM_039104568.1XP_038960496.1  glycerol-3-phosphate acyltransferase 2, mitochondrial isoform X2

    UniProtKB/TrEMBL
    A0A8I5ZY97
    Conserved Domains (1) summary
    cd07993
    Location:176387
    LPLAT_DHAPAT-like; Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: GPAT-like
  4. XM_063283330.1XP_063139400.1  glycerol-3-phosphate acyltransferase 2, mitochondrial isoform X4

    UniProtKB/TrEMBL
    A0A8I5ZY97

RNA

  1. XR_005501820.1 RNA Sequence

  2. XR_010064581.1 RNA Sequence

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