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Zfand5 zinc finger AN1-type containing 5 [ Rattus norvegicus (Norway rat) ]

Gene ID: 293960, updated on 13-Apr-2024

Summary

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Official Symbol
Zfand5provided by RGD
Official Full Name
zinc finger AN1-type containing 5provided by RGD
Primary source
RGD:1310776
See related
Ensembl:ENSRNOG00000018107 AllianceGenome:RGD:1310776
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Zfp216
Summary
Predicted to enable DNA binding activity and zinc ion binding activity. Predicted to act upstream of or within several processes, including face development; fibroblast migration; and platelet-derived growth factor receptor signaling pathway. Predicted to be located in cytoplasm. Orthologous to human ZFAND5 (zinc finger AN1-type containing 5). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Muscle (RPKM 674.0), Adrenal (RPKM 412.1) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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Location:
1q51
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (228191064..228206947)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (218765735..218780391)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (238842506..238854030)

Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene Neighboring gene uncharacterized LOC134483973 Neighboring gene uncharacterized LOC102551544 Neighboring gene uncharacterized LOC103691306 Neighboring gene uncharacterized LOC120100000 Neighboring gene small nucleolar RNA SNORA44 Neighboring gene guanine deaminase

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. PDGF signaling specificity is mediated through multiple immediate early genes. Schmahl J, et al. Nat Genet, 2007 Jan. PMID 17143286
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in face development IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within face development ISO
Inferred from Sequence Orthology
more info
  
involved_in fibroblast migration IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within fibroblast migration ISO
Inferred from Sequence Orthology
more info
  
involved_in in utero embryonic development IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within in utero embryonic development ISO
Inferred from Sequence Orthology
more info
  
involved_in platelet-derived growth factor receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within platelet-derived growth factor receptor signaling pathway ISO
Inferred from Sequence Orthology
more info
  
involved_in respiratory system process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within respiratory system process ISO
Inferred from Sequence Orthology
more info
  
involved_in skeletal system morphogenesis IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within skeletal system morphogenesis ISO
Inferred from Sequence Orthology
more info
  
involved_in smooth muscle tissue development IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within smooth muscle tissue development ISO
Inferred from Sequence Orthology
more info
  
involved_in vasculature development IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within vasculature development ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
AN1-type zinc finger protein 5
Names
zinc finger protein 216
zinc finger, AN1-type domain 5

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001401398.2 → NP_001388327.1  AN1-type zinc finger protein 5

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000001
    UniProtKB/Swiss-Prot
    B5DF11
    Related
    ENSRNOP00000024583.4, ENSRNOT00000024583.6

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086019.1 Reference GRCr8

    Range
    228191064..228206947
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039108958.2 → XP_038964886.1  AN1-type zinc finger protein 5 isoform X1

    UniProtKB/Swiss-Prot
    B5DF11
    UniProtKB/TrEMBL
    A0A8I5YBX2
    Related
    ENSRNOP00000076810.1
    Conserved Domains (2) summary
    smart00154
    Location:154 → 191
    ZnF_AN1; AN1-like Zinc finger
    pfam01754
    Location:12 → 34
    zf-A20; A20-like zinc finger

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001106356.1: Suppressed sequence

    Description
    NM_001106356.1: This RefSeq was removed because currently there is insufficient support for the transcript.
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
B5DF11.1 GenPept UniProtKB/Swiss-Prot:B5DF11

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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