Ugt2a3 UDP glucuronosyltransferase family 2 member A3 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Ugt2a3provided by RGD
Official Full Name: UDP glucuronosyltransferase family 2 member A3provided by RGD
Primary source: RGD:1308444
See related: Ensembl:ENSRNOG00000001973 AllianceGenome:RGD:1308444
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: RGD1308444
Summary: Predicted to enable glucuronosyltransferase activity. Predicted to be involved in cellular glucuronidation. Predicted to be integral component of membrane. Predicted to be active in intracellular membrane-bounded organelle. Orthologous to human UGT2A3 (UDP glucuronosyltransferase family 2 member A3). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Restricted expression toward (RPKM 554.7) See more
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Genomic context

Location:: 14p21

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	14	NC_086032.1 (20851970..20869974)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	14	NC_051349.1 (20572793..20590795)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	14	NC_005113.4 (22251507..22267899)

Chromosome 14 - NC_086032.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables glucuronosyltransferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables glucuronosyltransferase activity	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in cellular glucuronidation	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: UDP-glucuronosyltransferase 2A3

Names: UDP glucuronosyltransferase 2 family, polypeptide A3

NP_001129341.1

EC 2.4.1.17

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001135869.2 → NP_001129341.1 UDP-glucuronosyltransferase 2A3 precursor

Status: VALIDATED

Source sequence(s)

JAXUCZ010000014

UniProtKB/TrEMBL

A0A0G2JW02, A6KU29

Related

ENSRNOP00000069688.2, ENSRNOT00000087991.2

Conserved Domains (2) summary

PHA03392
Location:268 → 506

egt; ecdysteroid UDP-glucosyltransferase; Provisional

pfam00201
Location:25 → 519

UDPGT; UDP-glucoronosyl and UDP-glucosyl transferase