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F13b coagulation factor XIII B chain [ Rattus norvegicus (Norway rat) ]

Gene ID: 289055, updated on 13-Apr-2024

Summary

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Official Symbol
F13bprovided by RGD
Official Full Name
coagulation factor XIII B chainprovided by RGD
Primary source
RGD:1311668
See related
Ensembl:ENSRNOG00000012613 AllianceGenome:RGD:1311668
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to be involved in blood coagulation. Orthologous to human F13B (coagulation factor XIII B chain). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Restricted expression toward (RPKM 1190.8) See more
Orthologs
human mouse all
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Genomic context

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Location:
13q13
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 13 NC_086031.1 (53681639..53707114)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 13 NC_051348.1 (51130908..51156383)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 13 NC_005112.4 (56598891..56623132)

Chromosome 13 - NC_086031.1Genomic Context describing neighboring genes Neighboring gene zinc finger and BTB domain containing 41 Neighboring gene assembly factor for spindle microtubules Neighboring gene U4 spliceosomal RNA Neighboring gene complement factor H-related 2 Neighboring gene complement factor H-related 2-like 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Mutations affecting disulphide bonds contribute to a fairly common prevalence of F13B gene defects: results of a genetic study in 14 families with factor XIII B deficiency. Ivaskevicius V, et al. Haemophilia, 2010 Jul 1. PMID 20331752
  2. Administration of factor XIII B subunit increased plasma factor XIII A subunit levels in factor XIII B subunit knock-out mice. Souri M, et al. Int J Hematol, 2008 Jan. PMID 18224415
  3. Fibrinogen and fibrin structure and functions. Mosesson MW. J Thromb Haemost, 2005 Aug. PMID 16102057
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
involved_in blood coagulation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in blood coagulation ISO
Inferred from Sequence Orthology
more info
  
involved_in blood coagulation, fibrin clot formation ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
coagulation factor XIII B chain
Names
coagulation factor XIII, B polypeptide
coagulation factor XIII, beta subunit
NP_001388239.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001401310.1 → NP_001388239.1  coagulation factor XIII B chain precursor

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000013
    UniProtKB/TrEMBL
    B1H260, F6Q1N1
    Related
    ENSRNOP00000016944.8, ENSRNOT00000016944.8

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086031.1 Reference GRCr8

    Range
    53681639..53707114
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001105956.1: Suppressed sequence

    Description
    NM_001105956.1: This RefSeq was removed because currently there is insufficient support for the transcript.
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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