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MAP2K6 mitogen-activated protein kinase kinase 6 [ Bos taurus (cattle) ]

Gene ID: 286883, updated on 3-Apr-2024

Summary

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Official Symbol
MAP2K6provided by VGNC
Official Full Name
mitogen-activated protein kinase kinase 6provided by VGNC
Primary source
VGNC:VGNC:31187
See related
BGD:BT13937; Ensembl:ENSBTAG00000001609
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 19
Exon count:
17
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 19 NC_037346.1 (61130409..61236793, complement)

Chromosome 19 - NC_037346.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC112442736 Neighboring gene uncharacterized LOC112442737 Neighboring gene uncharacterized LOC132343137 Neighboring gene uncharacterized LOC104975164 Neighboring gene proline-rich protein 2-like Neighboring gene ATP binding cassette subfamily A member 5

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037346.1 Chromosome 19 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Sequence evaluation of four pooled-tissue normalized bovine cDNA libraries and construction of a gene index for cattle. Smith TP, et al. Genome Res, 2001 Apr. PMID 11282978, Free PMC Article
  2. Characterization of 954 bovine full-CDS cDNA sequences. Harhay GP, et al. BMC Genomics, 2005 Nov 23. PMID 16305752, Free PMC Article
  3. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables MAP kinase kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in MAPK cascade IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
dual specificity mitogen-activated protein kinase kinase 6
Names
MAP kinase kinase 6
MAPK/ERK kinase 6
MAPKK 6
MEK 6
NP_001029217.1
XP_005221398.1
XP_005221399.1
XP_059733732.1
XP_059733734.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001034045.1 → NP_001029217.1  dual specificity mitogen-activated protein kinase kinase 6

    See identical proteins and their annotated locations for NP_001029217.1

    Status: PROVISIONAL

    Source sequence(s)
    BT020798
    UniProtKB/Swiss-Prot
    Q5E9X2
    UniProtKB/TrEMBL
    A0A3Q1M703
    Related
    ENSBTAP00000002115.2, ENSBTAT00000002115.3
    Conserved Domains (1) summary
    cd06617
    Location:51 → 333
    PKc_MKK3_6; Catalytic domain of the dual-specificity Protein Kinases, Mitogen-activated protein Kinase Kinases 3 and 6

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037346.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    61130409..61236793 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005221341.5 → XP_005221398.1  dual specificity mitogen-activated protein kinase kinase 6 isoform X2

    UniProtKB/TrEMBL
    A0A3Q1M703
    Related
    ENSBTAP00000087793.1, ENSBTAT00000126669.1
    Conserved Domains (2) summary
    cd06617
    Location:55 → 337
    PKc_MKK3_6; Catalytic domain of the dual-specificity Protein Kinases, Mitogen-activated protein Kinase Kinases 3 and 6
    smart00220
    Location:58 → 318
    S_TKc; Serine/Threonine protein kinases, catalytic domain

  2. XM_005221342.5 → XP_005221399.1  dual specificity mitogen-activated protein kinase kinase 6 isoform X3

    UniProtKB/TrEMBL
    A0A3Q1LLK9, A0A3Q1M703
    Related
    ENSBTAP00000088215.1, ENSBTAT00000092625.1
    Conserved Domains (2) summary
    cd06617
    Location:50 → 332
    PKc_MKK3_6; Catalytic domain of the dual-specificity Protein Kinases, Mitogen-activated protein Kinase Kinases 3 and 6
    smart00220
    Location:53 → 313
    S_TKc; Serine/Threonine protein kinases, catalytic domain

  3. XM_059877749.1 → XP_059733732.1  dual specificity mitogen-activated protein kinase kinase 6 isoform X1

  4. XM_059877751.1 → XP_059733734.1  dual specificity mitogen-activated protein kinase kinase 6 isoform X4

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5E9X2.1 GenPept UniProtKB/Swiss-Prot:Q5E9X2

Gene LinkOut

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