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GNA11 G protein subunit alpha 11 [ Bos taurus (cattle) ]

Gene ID: 281788, updated on 3-Apr-2024

Summary

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Official Symbol
GNA11provided by VGNC
Official Full Name
G protein subunit alpha 11provided by VGNC
Primary source
VGNC:VGNC:29444
See related
BGD:BT10608; Ensembl:ENSBTAG00000012181
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Also known as
HG1K
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 7
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 7 NC_037334.1 (20696675..20712494, complement)

Chromosome 7 - NC_037334.1Genomic Context describing neighboring genes Neighboring gene sphingosine-1-phosphate receptor 4 Neighboring gene G protein subunit alpha 15 Neighboring gene transfer RNA methionine (anticodon CAU) Neighboring gene uncharacterized LOC112447372 Neighboring gene TLE family member 5, transcriptional modulator Neighboring gene TLE family member 2, transcriptional corepressor Neighboring gene TLE family member 6, subcortical maternal complex member

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037334.1 Chromosome 7 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. G protein-coupled receptor Kinase 2/G alpha q/11 interaction. A novel surface on a regulator of G protein signaling homology domain for binding G alpha subunits. Sterne-Marr R, et al. J Biol Chem, 2003 Feb 21. PMID 12427730
  2. Identification of two novel GTP-binding protein alpha-subunits that lack apparent ADP-ribosylation sites for pertussis toxin. Nakamura F, et al. J Biol Chem, 1991 Jul 5. PMID 1905731
  3. Selective regulation of Galpha(q/11) by an RGS domain in the G protein-coupled receptor kinase, GRK2. Carman CV, et al. J Biol Chem, 1999 Nov 26. PMID 10567430
  4. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. G protein-coupled receptor Kinase 2 reacts with this protein's signaling homology domain for binding G protein subunits
    Title: G protein-coupled receptor Kinase 2/G alpha q/11 interaction. A novel surface on a regulator of G protein signaling homology domain for binding G alpha subunits.
Submit: New GeneRIF Correction

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • MGC128352

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables G protein-coupled receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables G-protein beta/gamma-subunit complex binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables GTPase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables guanyl nucleotide binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in action potential IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in adenylate cyclase-modulating G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phospholipase C-activating dopamine receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of heterotrimeric G-protein complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
guanine nucleotide-binding protein subunit alpha-11
Names
G-protein subunit GL2 alpha
g alpha-11
heterotrimeric guanine nucleotide-binding protein 1K

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_174322.5 → NP_776747.2  guanine nucleotide-binding protein subunit alpha-11

    Status: VALIDATED

    Source sequence(s)
    NKLS02000007
    UniProtKB/Swiss-Prot
    P38409, Q2TA47
    Related
    ENSBTAP00000074164.1, ENSBTAT00000085254.2

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037334.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    20696675..20712494 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P38409.2 GenPept UniProtKB/Swiss-Prot:P38409

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.