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CALD1 caldesmon 1 [ Bos taurus (cattle) ]

Gene ID: 281660, updated on 5-Mar-2024

Summary

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Official Symbol
CALD1provided by VGNC
Official Full Name
caldesmon 1provided by VGNC
Primary source
VGNC:VGNC:26706
See related
BGD:BT27319; Ensembl:ENSBTAG00000013953
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 4
Exon count:
22
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 4 NC_037331.1 (98449568..98681120)

Chromosome 4 - NC_037331.1Genomic Context describing neighboring genes Neighboring gene aldo-keto reductase family 1 member B10 Neighboring gene bisphosphoglycerate mutase Neighboring gene uncharacterized LOC104972216 Neighboring gene AGBL carboxypeptidase 3 Neighboring gene U6 spliceosomal RNA Neighboring gene transmembrane protein 140 Neighboring gene cell cycle regulator of NHEJ

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037331.1 Chromosome 4 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Identification of multiple genes in bovine retinal pericytes altered by exposure to elevated levels of glucose by using mRNA differential display. Aiello LP, et al. Proc Natl Acad Sci U S A, 1994 Jun 21. PMID 8016144, Free PMC Article
  2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables actin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calmodulin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables myosin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in actin filament bundle assembly IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in angiogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in muscle contraction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in actin cytoskeleton IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
non-muscle caldesmon
Names
CDM
L-caldesmon
caldesmon, smooth muscle

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_174258.2 → NP_776683.1  non-muscle caldesmon

    See identical proteins and their annotated locations for NP_776683.1

    Status: PROVISIONAL

    Source sequence(s)
    AY154474
    UniProtKB/TrEMBL
    A0A3Q1LTX4, Q8HYY3
    Related
    ENSBTAP00000018566.5, ENSBTAT00000018566.6
    Conserved Domains (1) summary
    pfam02029
    Location:260 → 522
    Caldesmon; Caldesmon

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037331.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    98449568..98681120
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024990452.1 → XP_024846220.1  non-muscle caldesmon isoform X1

    Conserved Domains (2) summary
    pfam02029
    Location:517 → 776
    Caldesmon
    cl26511
    Location:147 → 629
    Neuromodulin_N; Gap junction protein N-terminal region

  2. XM_024990454.1 → XP_024846222.1  non-muscle caldesmon isoform X1

    Conserved Domains (2) summary
    pfam02029
    Location:517 → 776
    Caldesmon
    cl26511
    Location:147 → 629
    Neuromodulin_N; Gap junction protein N-terminal region

  3. XM_024990451.2 → XP_024846219.1  non-muscle caldesmon isoform X1

    Conserved Domains (2) summary
    pfam02029
    Location:517 → 776
    Caldesmon
    cl26511
    Location:147 → 629
    Neuromodulin_N; Gap junction protein N-terminal region

  4. XM_024990450.2 → XP_024846218.1  non-muscle caldesmon isoform X1

    Conserved Domains (2) summary
    pfam02029
    Location:517 → 776
    Caldesmon
    cl26511
    Location:147 → 629
    Neuromodulin_N; Gap junction protein N-terminal region

  5. XM_005205755.5 → XP_005205812.1  non-muscle caldesmon isoform X2

    See identical proteins and their annotated locations for XP_005205812.1

    Conserved Domains (1) summary
    pfam02029
    Location:514 → 776
    Caldesmon; Caldesmon

  6. XM_024990458.2 → XP_024846226.1  non-muscle caldesmon isoform X5

    UniProtKB/TrEMBL
    A0A3Q1LTX4
    Conserved Domains (1) summary
    pfam02029
    Location:263 → 522
    Caldesmon

  7. XM_005205759.5 → XP_005205816.1  non-muscle caldesmon isoform X6

    See identical proteins and their annotated locations for XP_005205816.1

    UniProtKB/TrEMBL
    A0A3Q1LTX4, F1MLW0
    Conserved Domains (1) summary
    pfam02029
    Location:260 → 522
    Caldesmon; Caldesmon

  8. XM_024990455.2 → XP_024846223.1  non-muscle caldesmon isoform X1

    Conserved Domains (2) summary
    pfam02029
    Location:517 → 776
    Caldesmon
    cl26511
    Location:147 → 629
    Neuromodulin_N; Gap junction protein N-terminal region

  9. XM_059885401.1 → XP_059741384.1  non-muscle caldesmon isoform X4

  10. XM_024990456.2 → XP_024846224.1  non-muscle caldesmon isoform X1

    Related
    ENSBTAP00000101112.1, ENSBTAT00000122708.1
    Conserved Domains (2) summary
    pfam02029
    Location:517 → 776
    Caldesmon
    cl26511
    Location:147 → 629
    Neuromodulin_N; Gap junction protein N-terminal region

  11. XM_024990459.2 → XP_024846227.1  non-muscle caldesmon isoform X5

    UniProtKB/TrEMBL
    A0A3Q1LTX4
    Conserved Domains (1) summary
    pfam02029
    Location:263 → 522
    Caldesmon

  12. XM_010804515.3 → XP_010802817.1  non-muscle caldesmon isoform X6

    See identical proteins and their annotated locations for XP_010802817.1

    UniProtKB/TrEMBL
    A0A3Q1LTX4, F1MLW0
    Conserved Domains (1) summary
    pfam02029
    Location:260 → 522
    Caldesmon; Caldesmon

  13. XM_024990457.2 → XP_024846225.1  non-muscle caldesmon isoform X3

    Conserved Domains (2) summary
    pfam02029
    Location:511 → 770
    Caldesmon
    cl26511
    Location:141 → 623
    Neuromodulin_N; Gap junction protein N-terminal region

  14. XM_024990460.2 → XP_024846228.1  non-muscle caldesmon isoform X7

    UniProtKB/TrEMBL
    A0A3Q1LTX4
    Conserved Domains (1) summary
    pfam02029
    Location:257 → 516
    Caldesmon

  15. XM_010804516.2 → XP_010802818.1  non-muscle caldesmon isoform X8

    UniProtKB/TrEMBL
    A0A3Q1LTX4
    Conserved Domains (1) summary
    pfam02029
    Location:254 → 516
    Caldesmon; Caldesmon
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q27976.1 GenPept UniProtKB/Swiss-Prot:Q27976

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