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ADCY1 adenylate cyclase 1 [ Bos taurus (cattle) ]

Gene ID: 281601, updated on 5-Mar-2024

Summary

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Official Symbol
ADCY1provided by VGNC
Official Full Name
adenylate cyclase 1provided by VGNC
Primary source
VGNC:VGNC:25642
See related
BGD:BT10524; Ensembl:ENSBTAG00000009520
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Also known as
AC1
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 4
Exon count:
20
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 4 NC_037331.1 (76174089..76273756, complement)

Chromosome 4 - NC_037331.1Genomic Context describing neighboring genes Neighboring gene insulin like growth factor binding protein 1 Neighboring gene coiled-coil domain containing 201 Neighboring gene receptor activity modifying protein 3 Neighboring gene whey acidic protein pseudogene

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037331.1 Chromosome 4 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Adenylyl cyclase amino acid sequence: possible channel- or transporter-like structure. Krupinski J, et al. Science, 1989 Jun 30. PMID 2472670
  2. Expression and characterization of calmodulin-activated (type I) adenylylcyclase. Tang WJ, et al. J Biol Chem, 1991 May 5. PMID 2022671
  3. Catalytic mechanism of the adenylyl and guanylyl cyclases: modeling and mutational analysis. Liu Y, et al. Proc Natl Acad Sci U S A, 1997 Dec 9. PMID 9391039, Free PMC Article
  4. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables adenylate cyclase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in adenylate cyclase-activating G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cAMP biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
adenylate cyclase type 1
Names
ATP pyrophosphate-lyase 1
adenylate cyclase 1 (brain)
adenylate cyclase type I
adenylyl cyclase 1
ca(2+)/calmodulin-activated adenylyl cyclase
NP_776654.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_174229.2 → NP_776654.1  adenylate cyclase type 1

    See identical proteins and their annotated locations for NP_776654.1

    Status: PROVISIONAL

    Source sequence(s)
    M25579
    UniProtKB/Swiss-Prot
    P19754
    Related
    ENSBTAP00000012528.6, ENSBTAT00000012528.6
    Conserved Domains (3) summary
    smart00044
    Location:260 → 455
    CYCc; Adenylyl- / guanylyl cyclase, catalytic domain
    pfam00211
    Location:862 → 1059
    Guanylate_cyc; Adenylate and Guanylate cyclase catalytic domain
    pfam16214
    Location:163 → 294
    AC_N; Adenylyl cyclase N-terminal extracellular and transmembrane region

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037331.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    76174089..76273756 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P19754.1 GenPept UniProtKB/Swiss-Prot:P19754

Gene LinkOut

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