U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

mt-Nd4l NADH dehdrogenase 4L, mitochondrial [ Rattus norvegicus (Norway rat) ]

Gene ID: 26200, updated on 11-Apr-2024

Summary

Official Symbol
mt-Nd4lprovided by RGD
Official Full Name
NADH dehdrogenase 4L, mitochondrialprovided by RGD
Primary source
RGD:620494
See related
AllianceGenome:RGD:620494
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus (strain: BN/SsNHsdMCW)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
ND4L
Summary
Predicted to enable NADH dehydrogenase (ubiquinone) activity. Predicted to be involved in ATP synthesis coupled electron transport. Predicted to be located in mitochondrial inner membrane. Predicted to be part of mitochondrial respiratory chain complex I. Human ortholog(s) of this gene implicated in Leber hereditary optic neuropathy and diabetes mellitus. Orthologous to human MT-ND4L (mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4L). [provided by Alliance of Genome Resources, Apr 2022]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Annotation release Status Assembly Chr Location
RS_2023_06 latest, but not current mRatBN7.2 (GCF_015227675.2) MT (non-nuclear) NC_001665.2 (9870..10166)
106 previous assembly Rnor_6.0 (GCF_000001895.5) MT (non-nuclear) NC_001665.2 (9870..10166)

Chromosome MT - NC_001665.2Genomic Context describing neighboring genes Neighboring gene NADH dehydrogenase subunit 3 Neighboring gene tRNA-Arg Neighboring gene NADH dehydrogenase subunit 4 Neighboring gene tRNA-His Neighboring gene tRNA-Ser Neighboring gene tRNA-Leu

Genomic regions, transcripts, and products

Pathways from PubChem

General gene information

  • Nd4l; NADH4L

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables NADH dehydrogenase (ubiquinone) activity ISO
Inferred from Sequence Orthology
more info
 
enables NADH dehydrogenase (ubiquinone) activity ISS
Inferred from Sequence or Structural Similarity
more info
 
Process Evidence Code Pubs
involved_in ATP synthesis coupled electron transport IEA
Inferred from Electronic Annotation
more info
 
involved_in biological_process ND
No biological Data available
more info
 
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in mitochondrial inner membrane ISO
Inferred from Sequence Orthology
more info
 
located_in mitochondrial inner membrane ISS
Inferred from Sequence or Structural Similarity
more info
 
part_of mitochondrial respiratory chain complex I IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of mitochondrial respiratory chain complex I ISO
Inferred from Sequence Orthology
more info
 
part_of mitochondrial respiratory chain complex I ISS
Inferred from Sequence or Structural Similarity
more info
 

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001665.2 Reference assembly

    Range
    9870..10166
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. YP_665637.1 NADH dehydrogenase subunit 4L (mitochondrion) [Rattus norvegicus]

    See identical proteins and their annotated locations for YP_665637.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P05507
    UniProtKB/TrEMBL
    Q06QA3, Q7H113
    Related
    ENSRNOP00000042064.3
    Conserved Domains (1) summary
    MTH00107
    Location:198
    ND4L; NADH dehydrogenase subunit 4L; Provisional