Cyp4a29 cytochrome P450, family 4, subfamily a, polypeptide 29 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Cyp4a29provided by MGI
Official Full Name: cytochrome P450, family 4, subfamily a, polypeptide 29provided by MGI
Primary source: MGI:MGI:3717143
See related: Ensembl:ENSMUSG00000083138 AllianceGenome:MGI:3717143
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Cyp4a29-ps
Summary: Predicted to enable 16-hydroxypalmitate dehydrogenase activity and monooxygenase activity. Predicted to be involved in fatty acid metabolic process; icosanoid biosynthetic process; and kidney development. Predicted to be located in apical plasma membrane; cytoplasm; and extracellular space. Predicted to be active in intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in hypertension. Orthologous to human CYP4A11 (cytochrome P450 family 4 subfamily A member 11) and CYP4A22 (cytochrome P450 family 4 subfamily A member 22). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Low expression observed in reference dataset See more
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Genomic context

Location:: 4 D1; 4 52.86 cM

Exon count:: 12

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	4	NC_000070.7 (115099241..115112138)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	4	NC_000070.6 (115242044..115254941)

Chromosome 4 - NC_000070.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables 16-hydroxypalmitate dehydrogenase activity	ISO Inferred from Sequence Orthology more info
enables alkane 1-monooxygenase activity	IBA Inferred from Biological aspect of Ancestor more info
enables alkane 1-monooxygenase activity	ISO Inferred from Sequence Orthology more info
enables arachidonic acid epoxygenase activity	ISO Inferred from Sequence Orthology more info
enables arachidonic acid monooxygenase activity	IBA Inferred from Biological aspect of Ancestor more info
enables leukotriene-B4 20-monooxygenase activity	ISO Inferred from Sequence Orthology more info
enables long-chain fatty acid omega-hydroxylase activity	ISO Inferred from Sequence Orthology more info
enables medium-chain fatty acid omega-hydroxylase activity	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in arachidonic acid metabolic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in icosanoid biosynthetic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in kidney development	IBA Inferred from Biological aspect of Ancestor more info
involved_in lauric acid metabolic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in linoleic acid metabolic process	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in apical plasma membrane	ISO Inferred from Sequence Orthology more info
located_in cytoplasm	ISO Inferred from Sequence Orthology more info
located_in extracellular space	ISO Inferred from Sequence Orthology more info
is_active_in intracellular membrane-bounded organelle	IBA Inferred from Biological aspect of Ancestor more info
located_in intracellular membrane-bounded organelle	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: cytochrome P450, family 4, subfamily a, polypeptide 29

Names: cytochrome P450, family 4, subfamily a, polypeptide 29, pseudogene

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001100183.2 → NP_001093653.1 cytochrome P450, family 4, subfamily a, polypeptide 29

Status: VALIDATED

Source sequence(s)

AL627227, AL645473

Consensus CDS

CCDS80146.1

UniProtKB/TrEMBL

A0A087WPC3

Related

ENSMUSP00000139717.2, ENSMUST00000118278.2

Conserved Domains (1) summary

pfam00067
Location:52 → 503

p450; Cytochrome P450