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Smarca4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 [ Mus musculus (house mouse) ]

Gene ID: 20586, updated on 4-Jan-2025

Summary

Official Symbol
Smarca4provided by MGI
Official Full Name
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4provided by MGI
Primary source
MGI:MGI:88192
See related
Ensembl:ENSMUSG00000032187 AllianceGenome:MGI:88192
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Brg1; BAF190A; SW1/SNF; HP1-BP72; SNF2beta; b2b692Clo; b2b508.1Clo
Summary
Enables several functions, including ATP hydrolysis activity; DNA polymerase binding activity; and nucleic acid binding activity. Involved in nervous system development; positive regulation of Wnt signaling pathway; and positive regulation of metabolic process. Acts upstream of or within with a negative effect on gene expression. Acts upstream of or within several processes, including blastocyst development; circulatory system development; and erythrocyte differentiation. Located in euchromatin; male germ cell nucleus; and perichromatin fibrils. Part of SWI/SNF complex; nBAF complex; and npBAF complex. Is active in nucleus. Is expressed in several structures, including alimentary system; central nervous system; early conceptus; genitourinary system; and sensory organ. Used to study breast cancer. Human ortholog(s) of this gene implicated in Coffin-Siris syndrome 4; hepatocellular carcinoma; lung non-small cell carcinoma; and rhabdoid tumor predisposition syndrome 2. Orthologous to human SMARCA4 (SWI/SNF related BAF chromatin remodeling complex subunit ATPase 4). [provided by Alliance of Genome Resources, Jan 2025]
Expression
Ubiquitous expression in whole brain E14.5 (RPKM 48.7), CNS E14 (RPKM 45.5) and 28 other tissues See more
Orthologs
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Genomic context

See Smarca4 in Genome Data Viewer
Location:
9 A3; 9 7.84 cM
Exon count:
37
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (21527377..21615526)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (21616106..21704230)

Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E3818 Neighboring gene predicted gene 7904 Neighboring gene microRNA 1946b Neighboring gene CapStarr-seq enhancer MGSCv37_chr9:21429854-21430055 Neighboring gene CapStarr-seq enhancer MGSCv37_chr9:21456989-21457190 Neighboring gene STARR-seq mESC enhancer starr_23507 Neighboring gene predicted gene, 26511 Neighboring gene STARR-positive B cell enhancer ABC_E10537 Neighboring gene STARR-positive B cell enhancer ABC_E1109 Neighboring gene low density lipoprotein receptor

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

Interactions

General gene information

Gene Ontology Provided by MGI

Items 1 - 25 of 28
Function Evidence Code Pubs
enables ATP binding  
enables ATP hydrolysis activity PubMed 
enables ATP hydrolysis activity PubMed 
enables ATP-dependent activity, acting on DNA  
enables ATP-dependent chromatin remodeler activity PubMed 
enables DNA binding  
enables DNA polymerase binding PubMed 
enables DNA polymerase binding  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding PubMed 
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding PubMed 
enables Tat protein binding  
enables chromatin binding  
enables chromatin binding PubMed 
enables chromatin binding  
enables helicase activity  
enables histone binding  
enables lncRNA binding PubMed 
enables lysine-acetylated histone binding  
enables nuclear androgen receptor binding  
enables nucleosome array spacer activity  
enables p53 binding  
enables protein binding PubMed 
enables protein-containing complex binding  
enables transcription coactivator activity  
enables transcription coregulator binding  
enables transcription corepressor activity  
enables transcription corepressor activity  
enables transcription factor binding PubMed 
Items 1 - 25 of 28
Items 1 - 25 of 73
Process Evidence Code Pubs
acts_upstream_of_or_within aorta development PubMed 
acts_upstream_of_or_within aortic smooth muscle cell differentiation PubMed 
acts_upstream_of_or_within blastocyst growth PubMed 
acts_upstream_of_or_within blastocyst hatching PubMed 
acts_upstream_of_or_within blood vessel development PubMed 
acts_upstream_of_or_within cell morphogenesis PubMed 
acts_upstream_of_or_within chromatin remodeling PubMed 
involved_in chromatin remodeling  
involved_in chromatin remodeling PubMed 
acts_upstream_of_or_within coronary vasculature development PubMed 
acts_upstream_of_or_within definitive erythrocyte differentiation PubMed 
acts_upstream_of_or_within embryonic hindlimb morphogenesis PubMed 
acts_upstream_of_or_within embryonic organ morphogenesis PubMed 
acts_upstream_of_or_within epidermis morphogenesis PubMed 
acts_upstream_of_or_within extracellular matrix organization PubMed 
acts_upstream_of_or_within forebrain development PubMed 
acts_upstream_of_or_within_negative_effect gene expression PubMed 
acts_upstream_of_or_within glial cell fate determination PubMed 
acts_upstream_of_or_within heart development PubMed 
acts_upstream_of_or_within heart trabecula formation PubMed 
involved_in heterochromatin formation  
acts_upstream_of_or_within hindbrain development PubMed 
acts_upstream_of_or_within in utero embryonic development PubMed 
acts_upstream_of_or_within keratinocyte differentiation PubMed 
acts_upstream_of_or_within lens fiber cell development PubMed 
acts_upstream_of_or_within liver development PubMed 
involved_in negative regulation of DNA-templated transcription  
involved_in negative regulation of androgen receptor signaling pathway  
acts_upstream_of_or_within negative regulation of apoptotic process PubMed 
involved_in negative regulation of cell differentiation PubMed 
involved_in negative regulation of cell growth  
acts_upstream_of_or_within negative regulation of transcription by RNA polymerase II PubMed 
involved_in nervous system development PubMed 
acts_upstream_of_or_within neurogenesis PubMed 
acts_upstream_of_or_within nucleosome assembly PubMed 
involved_in nucleosome disassembly  
acts_upstream_of_or_within outflow tract morphogenesis PubMed 
acts_upstream_of_or_within pharyngeal arch artery morphogenesis PubMed 
involved_in positive regulation by host of viral transcription  
acts_upstream_of_or_within positive regulation of DNA binding PubMed 
involved_in positive regulation of DNA-binding transcription factor activity  
involved_in positive regulation of DNA-templated transcription  
involved_in positive regulation of T cell differentiation PubMed 
involved_in positive regulation of Wnt signaling pathway PubMed 
involved_in positive regulation of Wnt signaling pathway  
acts_upstream_of_or_within positive regulation of cell differentiation PubMed 
involved_in positive regulation of cell differentiation PubMed 
acts_upstream_of_or_within positive regulation of cell population proliferation PubMed 
involved_in positive regulation of cell population proliferation PubMed 
involved_in positive regulation of cold-induced thermogenesis PubMed 
involved_in positive regulation of double-strand break repair PubMed 
involved_in positive regulation of glucose mediated signaling pathway  
involved_in positive regulation of miRNA transcription  
involved_in positive regulation of myoblast differentiation PubMed 
involved_in positive regulation of stem cell population maintenance PubMed 
involved_in positive regulation of transcription by RNA polymerase II  
involved_in positive regulation of transcription by RNA polymerase II PubMed 
acts_upstream_of_or_within positive regulation of transcription by RNA polymerase II PubMed 
acts_upstream_of_or_within positive regulation of transcription by RNA polymerase II PubMed 
involved_in positive regulation of transcription by RNA polymerase II  
involved_in positive regulation of transcription of nucleolar large rRNA by RNA polymerase I  
acts_upstream_of_or_within primitive erythrocyte differentiation PubMed 
involved_in regulation of G0 to G1 transition PubMed 
involved_in regulation of G1/S transition of mitotic cell cycle PubMed 
acts_upstream_of_or_within regulation of cell migration PubMed 
involved_in regulation of mitotic metaphase/anaphase transition PubMed 
involved_in regulation of nucleotide-excision repair PubMed 
involved_in regulation of transcription by RNA polymerase II PubMed 
acts_upstream_of_or_within stem cell population maintenance PubMed 
acts_upstream_of transcription by RNA polymerase II PubMed 
involved_in transcription initiation-coupled chromatin remodeling PubMed 
acts_upstream_of_or_within vasculogenesis PubMed 
acts_upstream_of_or_within ventricular septum development PubMed 
Items 1 - 25 of 73
Items 1 - 20 of 30
Component Evidence Code Pubs
part_of GBAF complex PubMed 
part_of RSC-type complex PubMed 
part_of SWI/SNF complex PubMed 
part_of SWI/SNF complex  
part_of SWI/SNF complex PubMed 
part_of SWI/SNF complex PubMed 
part_of SWI/SNF superfamily-type complex PubMed 
part_of bBAF complex PubMed 
located_in chromatin  
located_in chromatin  
located_in chromatin PubMed 
located_in euchromatin PubMed 
located_in fibrillar center  
located_in kinetochore PubMed 
located_in male germ cell nucleus PubMed 
part_of nBAF complex PubMed 
part_of nBAF complex PubMed 
part_of npBAF complex PubMed 
part_of npBAF complex  
part_of npBAF complex PubMed 
located_in nuclear matrix PubMed 
NOT located_in nucleolus PubMed 
located_in nucleolus  
located_in nucleoplasm  
located_in nucleoplasm  
is_active_in nucleus  
is_active_in nucleus PubMed 
located_in nucleus PubMed 
located_in nucleus  
located_in perichromatin fibrils PubMed 
Items 1 - 20 of 30

General protein information

Preferred Names
transcription activator BRG1
Names
ATP-dependent helicase SMARCA4
BRG1-associated factor 190A
SNF2-beta
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4
protein brahma homolog 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001174078.1NP_001167549.1  transcription activator BRG1 isoform 1

    See identical proteins and their annotated locations for NP_001167549.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) lacks an alternate in-frame exon and uses an alternate in-frame splice junction compared to variant 4. The resulting isoform (1) has the same N- and C-termini but is shorter compared to isoform 4.
    Source sequence(s)
    AK160825, BC079560
    Consensus CDS
    CCDS52737.1
    UniProtKB/TrEMBL
    A0A0R4J170
    Related
    ENSMUSP00000096547.4, ENSMUST00000098948.10
    Conserved Domains (9) summary
    cd05516
    Location:14281534
    Bromo_SNF2L2; Bromodomain, SNF2L2-like subfamily, specific to animals. SNF2L2 (SNF2-alpha) or SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 is a global transcriptional activator, which cooperates with nuclear hormone ...
    smart00592
    Location:612656
    BRK; domain in transcription and CHROMO domain helicases
    PLN03142
    Location:7501232
    PLN03142; Probable chromatin-remodeling complex ATPase chain; Provisional
    COG1196
    Location:370570
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam09606
    Location:42217
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    cd18062
    Location:731981
    DEXHc_SMARCA4; DEXH-box helicase domain of SMARCA4
    pfam07529
    Location:461531
    HSA
    pfam08880
    Location:171205
    QLQ
    pfam14619
    Location:12911356
    SnAC; Snf2-ATP coupling, chromatin remodelling complex
  2. NM_001174079.1NP_001167550.1  transcription activator BRG1 isoform 3

    See identical proteins and their annotated locations for NP_001167550.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) lacks an alternate in-frame exon and uses an alternate in-frame splice junction compared to variant 4. The resulting isoform (3) has the same N- and C-termini but is shorter compared to isoform 4.
    Source sequence(s)
    AK160825, AK166837, BC079560
    Consensus CDS
    CCDS57662.1
    UniProtKB/Swiss-Prot
    Q3TKT4, Q3TUD7, Q6AXG8
    Related
    ENSMUSP00000133922.2, ENSMUST00000174008.8
    Conserved Domains (9) summary
    cd05516
    Location:14251530
    Bromo_SNF2L2; Bromodomain, SNF2L2-like subfamily, specific to animals. SNF2L2 (SNF2-alpha) or SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 is a global transcriptional activator, which cooperates with nuclear hormone ...
    smart00592
    Location:612656
    BRK; domain in transcription and CHROMO domain helicases
    PLN03142
    Location:7501232
    PLN03142; Probable chromatin-remodeling complex ATPase chain; Provisional
    COG1196
    Location:370570
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam09606
    Location:42217
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    cd18062
    Location:731981
    DEXHc_SMARCA4; DEXH-box helicase domain of SMARCA4
    pfam07529
    Location:461531
    HSA
    pfam08880
    Location:171205
    QLQ
    pfam14619
    Location:12911356
    SnAC; Snf2-ATP coupling, chromatin remodelling complex
  3. NM_001357764.1NP_001344693.1  transcription activator BRG1 isoform 4

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) represents the longest transcript and encodes the longest isoform (4).
    Source sequence(s)
    AC161371
    Conserved Domains (9) summary
    cd05516
    Location:14581564
    Bromo_SNF2L2; Bromodomain, SNF2L2-like subfamily, specific to animals. SNF2L2 (SNF2-alpha) or SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 is a global transcriptional activator, which cooperates with nuclear hormone ...
    smart00592
    Location:612656
    BRK; domain in transcription and CHROMO domain helicases
    PLN03142
    Location:7501232
    PLN03142; Probable chromatin-remodeling complex ATPase chain; Provisional
    COG1196
    Location:370570
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam09606
    Location:42217
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    cd18062
    Location:731981
    DEXHc_SMARCA4; DEXH-box helicase domain of SMARCA4
    pfam07529
    Location:461531
    HSA
    pfam08880
    Location:171205
    QLQ
    pfam14619
    Location:13241389
    SnAC; Snf2-ATP coupling, chromatin remodelling complex
  4. NM_011417.3NP_035547.2  transcription activator BRG1 isoform 2

    See identical proteins and their annotated locations for NP_035547.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an alternate in-frame exon compared to variant 4. The resulting isoform (2) has the same N- and C-termini but is shorter compared to isoform 4..
    Source sequence(s)
    AK160825, BC079560
    Consensus CDS
    CCDS22909.1
    UniProtKB/Swiss-Prot
    Q3TKT4
    Related
    ENSMUSP00000034707.9, ENSMUST00000034707.15
    Conserved Domains (9) summary
    cd05516
    Location:14251531
    Bromo_SNF2L2; Bromodomain, SNF2L2-like subfamily, specific to animals. SNF2L2 (SNF2-alpha) or SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 is a global transcriptional activator, which cooperates with nuclear hormone ...
    smart00592
    Location:612656
    BRK; domain in transcription and CHROMO domain helicases
    PLN03142
    Location:7501232
    PLN03142; Probable chromatin-remodeling complex ATPase chain; Provisional
    COG1196
    Location:370570
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam09606
    Location:42217
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    cd18062
    Location:731981
    DEXHc_SMARCA4; DEXH-box helicase domain of SMARCA4
    pfam07529
    Location:461531
    HSA
    pfam08880
    Location:171205
    QLQ
    pfam14619
    Location:12911356
    SnAC; Snf2-ATP coupling, chromatin remodelling complex

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000075.7 Reference GRCm39 C57BL/6J

    Range
    21527377..21615526
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011242438.3XP_011240740.1  transcription activator BRG1 isoform X1

    See identical proteins and their annotated locations for XP_011240740.1

    Conserved Domains (9) summary
    cd05516
    Location:14611567
    Bromo_SNF2L2; Bromodomain, SNF2L2-like subfamily, specific to animals. SNF2L2 (SNF2-alpha) or SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 is a global transcriptional activator, which cooperates with nuclear hormone ...
    smart00592
    Location:612656
    BRK; domain in transcription and CHROMO domain helicases
    PLN03142
    Location:7501232
    PLN03142; Probable chromatin-remodeling complex ATPase chain; Provisional
    COG1196
    Location:370570
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam09606
    Location:42217
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    cd18062
    Location:731981
    DEXHc_SMARCA4; DEXH-box helicase domain of SMARCA4
    pfam07529
    Location:461531
    HSA
    pfam08880
    Location:171205
    QLQ
    pfam14619
    Location:13241389
    SnAC; Snf2-ATP coupling, chromatin remodelling complex
  2. XM_011242434.1XP_011240736.1  transcription activator BRG1 isoform X1

    See identical proteins and their annotated locations for XP_011240736.1

    Conserved Domains (9) summary
    cd05516
    Location:14611567
    Bromo_SNF2L2; Bromodomain, SNF2L2-like subfamily, specific to animals. SNF2L2 (SNF2-alpha) or SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 is a global transcriptional activator, which cooperates with nuclear hormone ...
    smart00592
    Location:612656
    BRK; domain in transcription and CHROMO domain helicases
    PLN03142
    Location:7501232
    PLN03142; Probable chromatin-remodeling complex ATPase chain; Provisional
    COG1196
    Location:370570
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam09606
    Location:42217
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    cd18062
    Location:731981
    DEXHc_SMARCA4; DEXH-box helicase domain of SMARCA4
    pfam07529
    Location:461531
    HSA
    pfam08880
    Location:171205
    QLQ
    pfam14619
    Location:13241389
    SnAC; Snf2-ATP coupling, chromatin remodelling complex
  3. XM_011242435.1XP_011240737.1  transcription activator BRG1 isoform X2

    Conserved Domains (9) summary
    cd05516
    Location:14611566
    Bromo_SNF2L2; Bromodomain, SNF2L2-like subfamily, specific to animals. SNF2L2 (SNF2-alpha) or SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 is a global transcriptional activator, which cooperates with nuclear hormone ...
    smart00592
    Location:612656
    BRK; domain in transcription and CHROMO domain helicases
    PLN03142
    Location:7501232
    PLN03142; Probable chromatin-remodeling complex ATPase chain; Provisional
    COG1196
    Location:370570
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam09606
    Location:42217
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    cd18062
    Location:731981
    DEXHc_SMARCA4; DEXH-box helicase domain of SMARCA4
    pfam07529
    Location:461531
    HSA
    pfam08880
    Location:171205
    QLQ
    pfam14619
    Location:13241389
    SnAC; Snf2-ATP coupling, chromatin remodelling complex
  4. XM_006510122.2XP_006510185.2  transcription activator BRG1 isoform X3

    See identical proteins and their annotated locations for XP_006510185.2

    Conserved Domains (9) summary
    cd05516
    Location:14581564
    Bromo_SNF2L2; Bromodomain, SNF2L2-like subfamily, specific to animals. SNF2L2 (SNF2-alpha) or SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 is a global transcriptional activator, which cooperates with nuclear hormone ...
    smart00592
    Location:612656
    BRK; domain in transcription and CHROMO domain helicases
    PLN03142
    Location:7501232
    PLN03142; Probable chromatin-remodeling complex ATPase chain; Provisional
    COG1196
    Location:370570
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam09606
    Location:42217
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    cd18062
    Location:731981
    DEXHc_SMARCA4; DEXH-box helicase domain of SMARCA4
    pfam07529
    Location:461531
    HSA
    pfam08880
    Location:171205
    QLQ
    pfam14619
    Location:13241389
    SnAC; Snf2-ATP coupling, chromatin remodelling complex
  5. XM_011242436.1XP_011240738.1  transcription activator BRG1 isoform X4

    Conserved Domains (9) summary
    cd05516
    Location:14581563
    Bromo_SNF2L2; Bromodomain, SNF2L2-like subfamily, specific to animals. SNF2L2 (SNF2-alpha) or SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 is a global transcriptional activator, which cooperates with nuclear hormone ...
    smart00592
    Location:612656
    BRK; domain in transcription and CHROMO domain helicases
    PLN03142
    Location:7501232
    PLN03142; Probable chromatin-remodeling complex ATPase chain; Provisional
    COG1196
    Location:370570
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam09606
    Location:42217
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    cd18062
    Location:731981
    DEXHc_SMARCA4; DEXH-box helicase domain of SMARCA4
    pfam07529
    Location:461531
    HSA
    pfam08880
    Location:171205
    QLQ
    pfam14619
    Location:13241389
    SnAC; Snf2-ATP coupling, chromatin remodelling complex
  6. XM_006510117.2XP_006510180.2  transcription activator BRG1 isoform X6

    See identical proteins and their annotated locations for XP_006510180.2

    UniProtKB/TrEMBL
    A0A0R4J170
    Conserved Domains (9) summary
    cd05516
    Location:14281534
    Bromo_SNF2L2; Bromodomain, SNF2L2-like subfamily, specific to animals. SNF2L2 (SNF2-alpha) or SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 is a global transcriptional activator, which cooperates with nuclear hormone ...
    smart00592
    Location:612656
    BRK; domain in transcription and CHROMO domain helicases
    PLN03142
    Location:7501232
    PLN03142; Probable chromatin-remodeling complex ATPase chain; Provisional
    COG1196
    Location:370570
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam09606
    Location:42217
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    cd18062
    Location:731981
    DEXHc_SMARCA4; DEXH-box helicase domain of SMARCA4
    pfam07529
    Location:461531
    HSA
    pfam08880
    Location:171205
    QLQ
    pfam14619
    Location:12911356
    SnAC; Snf2-ATP coupling, chromatin remodelling complex
  7. XM_006510119.2XP_006510182.2  transcription activator BRG1 isoform X7

    See identical proteins and their annotated locations for XP_006510182.2

    UniProtKB/Swiss-Prot
    Q3TKT4
    Conserved Domains (9) summary
    cd05516
    Location:14251531
    Bromo_SNF2L2; Bromodomain, SNF2L2-like subfamily, specific to animals. SNF2L2 (SNF2-alpha) or SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 is a global transcriptional activator, which cooperates with nuclear hormone ...
    smart00592
    Location:612656
    BRK; domain in transcription and CHROMO domain helicases
    PLN03142
    Location:7501232
    PLN03142; Probable chromatin-remodeling complex ATPase chain; Provisional
    COG1196
    Location:370570
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam09606
    Location:42217
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    cd18062
    Location:731981
    DEXHc_SMARCA4; DEXH-box helicase domain of SMARCA4
    pfam07529
    Location:461531
    HSA
    pfam08880
    Location:171205
    QLQ
    pfam14619
    Location:12911356
    SnAC; Snf2-ATP coupling, chromatin remodelling complex
  8. XM_006510120.2XP_006510183.2  transcription activator BRG1 isoform X8

    See identical proteins and their annotated locations for XP_006510183.2

    UniProtKB/Swiss-Prot
    Q3TKT4, Q3TUD7, Q6AXG8
    Conserved Domains (9) summary
    cd05516
    Location:14251530
    Bromo_SNF2L2; Bromodomain, SNF2L2-like subfamily, specific to animals. SNF2L2 (SNF2-alpha) or SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 is a global transcriptional activator, which cooperates with nuclear hormone ...
    smart00592
    Location:612656
    BRK; domain in transcription and CHROMO domain helicases
    PLN03142
    Location:7501232
    PLN03142; Probable chromatin-remodeling complex ATPase chain; Provisional
    COG1196
    Location:370570
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam09606
    Location:42217
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    cd18062
    Location:731981
    DEXHc_SMARCA4; DEXH-box helicase domain of SMARCA4
    pfam07529
    Location:461531
    HSA
    pfam08880
    Location:171205
    QLQ
    pfam14619
    Location:12911356
    SnAC; Snf2-ATP coupling, chromatin remodelling complex
  9. XM_011242437.4XP_011240739.1  transcription activator BRG1 isoform X5

    Conserved Domains (9) summary
    cd05516
    Location:14811587
    Bromo_SNF2L2; Bromodomain, SNF2L2-like subfamily, specific to animals. SNF2L2 (SNF2-alpha) or SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 is a global transcriptional activator, which cooperates with nuclear hormone ...
    smart00592
    Location:632676
    BRK; domain in transcription and CHROMO domain helicases
    PLN03142
    Location:7701252
    PLN03142; Probable chromatin-remodeling complex ATPase chain; Provisional
    COG1196
    Location:390590
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam09606
    Location:62237
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    cd18062
    Location:7511001
    DEXHc_SMARCA4; DEXH-box helicase domain of SMARCA4
    pfam07529
    Location:481551
    HSA
    pfam08880
    Location:191225
    QLQ
    pfam14619
    Location:13441409
    SnAC; Snf2-ATP coupling, chromatin remodelling complex
  10. XM_030244151.1XP_030100011.1  transcription activator BRG1 isoform X9

    UniProtKB/TrEMBL
    Q3UI73
    Conserved Domains (4) summary
    cd05516
    Location:713819
    Bromo_SNF2L2; Bromodomain, SNF2L2-like subfamily, specific to animals. SNF2L2 (SNF2-alpha) or SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 is a global transcriptional activator, which cooperates with nuclear hormone ...
    PLN03142
    Location:2484
    PLN03142; Probable chromatin-remodeling complex ATPase chain; Provisional
    cd17996
    Location:3233
    DEXHc_SMARCA2_SMARCA4; DEXH-box helicase domain of SMARCA2 and SMARCA4
    pfam14619
    Location:576641
    SnAC; Snf2-ATP coupling, chromatin remodelling complex
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