Rpl7 ribosomal protein L7 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Rpl7provided by MGI
Official Full Name: ribosomal protein L7provided by MGI
Primary source: MGI:MGI:98073
See related: Ensembl:ENSMUSG00000043716 AllianceGenome:MGI:98073
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Rpl7a; Surf-3
Summary: Predicted to enable identical protein binding activity and nucleic acid binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Predicted to act upstream of or within translation. Located in synapse. Part of cytosolic large ribosomal subunit and polysome. Is expressed in several structures, including brain; early conceptus; female reproductive system; and liver. Orthologous to human RPL7 (ribosomal protein L7). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Broad expression in CNS E11.5 (RPKM 611.3), liver E14 (RPKM 581.9) and 25 other tissues See more
Orthologs: human all
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Genomic context

Location:: 1 A3; 1 4.94 cM

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	1	NC_000067.7 (16171519..16174657, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	1	NC_000067.6 (16101295..16104433, complement)

Chromosome 1 - NC_000067.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

Rpl7 (e-PCR), detects polymorphism
- UniSTS:516691

Rpl7 (e-PCR), detects polymorphism
- UniSTS:547466

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables 5S rRNA binding	ISO Inferred from Sequence Orthology more info
enables DNA binding	ISO Inferred from Sequence Orthology more info	PubMed
enables RNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables identical protein binding	ISO Inferred from Sequence Orthology more info	PubMed
enables mRNA binding	ISO Inferred from Sequence Orthology more info	PubMed
enables structural constituent of ribosome	IBA Inferred from Biological aspect of Ancestor more info
enables structural constituent of ribosome	IC Inferred by Curator more info	PubMed
enables structural constituent of ribosome	IDA Inferred from Direct Assay more info	PubMed
enables structural constituent of ribosome	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in cytoplasmic translation	NAS Non-traceable Author Statement more info	PubMed
involved_in maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	IBA Inferred from Biological aspect of Ancestor more info
involved_in rRNA processing	ISO Inferred from Sequence Orthology more info
involved_in ribosomal large subunit biogenesis	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within translation	IC Inferred by Curator more info	PubMed
involved_in translation at postsynapse	NAS Non-traceable Author Statement more info	PubMed
involved_in translation at presynapse	NAS Non-traceable Author Statement more info	PubMed

Component	Evidence Code	Pubs
located_in A band	ISO Inferred from Sequence Orthology more info
located_in cytoplasm	IDA Inferred from Direct Assay more info	PubMed
located_in cytosol	TAS Traceable Author Statement more info
part_of cytosolic large ribosomal subunit	IBA Inferred from Biological aspect of Ancestor more info
part_of cytosolic large ribosomal subunit	IDA Inferred from Direct Assay more info	PubMed
part_of cytosolic large ribosomal subunit	IPI Inferred from Physical Interaction more info	PubMed
part_of cytosolic large ribosomal subunit	ISO Inferred from Sequence Orthology more info
located_in cytosolic ribosome	ISO Inferred from Sequence Orthology more info
is_active_in postsynapse	NAS Non-traceable Author Statement more info	PubMed
is_active_in postsynaptic density	ISO Inferred from Sequence Orthology more info
is_active_in presynapse	NAS Non-traceable Author Statement more info	PubMed
part_of ribonucleoprotein complex	ISO Inferred from Sequence Orthology more info	PubMed
located_in ribosome	IDA Inferred from Direct Assay more info	PubMed
located_in ribosome	ISO Inferred from Sequence Orthology more info
is_active_in ribosome	NAS Non-traceable Author Statement more info	PubMed
is_active_in synapse	EXP Inferred from Experiment more info	PubMed
is_active_in synapse	IDA Inferred from Direct Assay more info	PubMed

General protein information

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Preferred Names: large ribosomal subunit protein uL30

Names: 60S ribosomal protein L7

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.