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Ptprf protein tyrosine phosphatase receptor type F [ Mus musculus (house mouse) ]

Gene ID: 19268, updated on 21-Apr-2024

Summary

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Official Symbol
Ptprfprovided by MGI
Official Full Name
protein tyrosine phosphatase receptor type Fprovided by MGI
Primary source
MGI:MGI:102695
See related
Ensembl:ENSMUSG00000033295 AllianceGenome:MGI:102695
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
LAR; LARS; RPTP-LAR
Summary
Enables chondroitin sulfate proteoglycan binding activity. Acts upstream of or within neuron projection regeneration and regulation of axon regeneration. Located in neuron projection and neuronal cell body. Is expressed in several structures, including adrenal gland; alimentary system epithelium; central nervous system; genitourinary system; and nasal cavity epithelium. Human ortholog(s) of this gene implicated in hyperinsulinism. Orthologous to human PTPRF (protein tyrosine phosphatase receptor type F). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in lung adult (RPKM 85.7), colon adult (RPKM 71.2) and 25 other tissues See more
Orthologs
human all
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Genomic context

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Location:
4 D2.1; 4 54.47 cM
Exon count:
37
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (118065410..118148602, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (118208213..118291405, complement)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene lysine (K)-specific demethylase 4A Neighboring gene STARR-positive B cell enhancer ABC_E1037 Neighboring gene CapStarr-seq enhancer MGSCv37_chr4:117852549-117852732 Neighboring gene predicted gene, 23382 Neighboring gene predicted gene, 54252 Neighboring gene STARR-seq mESC enhancer starr_11193 Neighboring gene STARR-seq mESC enhancer starr_11196 Neighboring gene microRNA 7226 Neighboring gene CapStarr-seq enhancer MGSCv37_chr4:117930044-117930297 Neighboring gene predicted gene, 40235 Neighboring gene predicted gene, 52705 Neighboring gene SZT2 subunit of KICSTOR complex Neighboring gene hydroxypyruvate isomerase (putative) Neighboring gene STARR-positive B cell enhancer ABC_E1281 Neighboring gene mediator complex subunit 8

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Regulation of Platelet Derived Growth Factor Signaling by Leukocyte Common Antigen-related (LAR) Protein Tyrosine Phosphatase: A Quantitative Phosphoproteomics Study. Sarhan AR, et al. Mol Cell Proteomics, 2016 Jun. PMID 27074791, Free PMC Article
  2. Role of CSPG receptor LAR phosphatase in restricting axon regeneration after CNS injury. Xu B, et al. Neurobiol Dis, 2015 Jan. PMID 25220840, Free PMC Article
  3. Leukocyte antigen-related inhibition attenuates palmitate-induced insulin resistance in muscle cells. Gorgani-Firuzjaee S, et al. J Endocrinol, 2012 Oct. PMID 22899729
  4. The LAR protein tyrosine phosphatase enables PDGF β-receptor activation through attenuation of the c-Abl kinase activity. Zheng W, et al. Cell Signal, 2011 Jun. PMID 21300149
  5. Regulatory role of leukocyte-common-antigen-related molecule (LAR) in thymocyte differentiation. Kondo S, et al. Eur J Immunol, 2010 May. PMID 20186877

See all (75) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. MiR-199a-3p Regulates the PTPRF/beta-Catenin Axis in Hair Follicle Development: Insights into the Pathogenic Mechanism of Alopecia Areata.
    Title: MiR-199a-3p Regulates the PTPRF/β-Catenin Axis in Hair Follicle Development: Insights into the Pathogenic Mechanism of Alopecia Areata.
  2. Intact synapse structure and function after combined knockout of PTPdelta, PTPsigma, and LAR.
    Title: Intact synapse structure and function after combined knockout of PTPδ, PTPσ, and LAR.
  3. We show that PTP-3, a LAR homolog in Caenorhabditis elegans, participates in Sema2A-regulated axon guidance. PTPdelta, a member of vertebrate LAR class PTPs, is involved in Sema3A-regulated cortical dendritic growth. In Sema3A signaling, PTPdelta activates Fyn and Src kinases by dephosphorylating their C-terminal Tyr residues.
    Title: Protein Tyrosine Phosphatase δ Mediates the Sema3A-Induced Cortical Basal Dendritic Arborization through the Activation of Fyn Tyrosine Kinase.
  4. loss of LAR activity resulted in reduced activity of CDK1.
    Title: LAR protein tyrosine phosphatase regulates focal adhesions through CDK1.
  5. Study has identified LAR as a regulator of key signaling pathways, including mTOR and JNK, and has significantly expanded the number of proteins regulated downstream of LAR phosphatase activity.
    Title: Regulation of Platelet Derived Growth Factor Signaling by Leukocyte Common Antigen-related (LAR) Protein Tyrosine Phosphatase: A Quantitative Phosphoproteomics Study.
  6. Chondroitin Sulfate Proteoglycans Negatively Modulate Spinal Cord Neural Precursor Cells by Signaling Through LAR and RPTPsigma and Modulation of the Rho/ROCK Pathway.
    Title: Chondroitin Sulfate Proteoglycans Negatively Modulate Spinal Cord Neural Precursor Cells by Signaling Through LAR and RPTPσ and Modulation of the Rho/ROCK Pathway.
  7. This study demonstrates the crucial role of LAR in restricting regrowth of injured CNS axons
    Title: Role of CSPG receptor LAR phosphatase in restricting axon regeneration after CNS injury.
  8. Ptprs and Ptprf deficiency affects mandibular cell proliferation.
    Title: Inactivation of LAR family phosphatase genes Ptprs and Ptprf causes craniofacial malformations resembling Pierre-Robin sequence.
  9. Inhibition of LAR attenuates palmitate-induced insulin resistance in myotubes.
    Title: Leukocyte antigen-related inhibition attenuates palmitate-induced insulin resistance in muscle cells.
  10. Deletion of LAR in knock-out mice or blockade of LAR with sequence-selective peptides significantly overcomes neurite growth restrictions of chondroitin sulfate proteoglycan in neuronal cultures.
    Title: Leukocyte common antigen-related phosphatase is a functional receptor for chondroitin sulfate proteoglycan axon growth inhibitors.
Submit: New GeneRIF Correction See all GeneRIFs (19)

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables cell adhesion molecule binding ISO
Inferred from Sequence Orthology
more info
  
enables chondroitin sulfate proteoglycan binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables heparin binding IEA
Inferred from Electronic Annotation
more info
  
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables insulin receptor binding ISO
Inferred from Sequence Orthology
more info
  
enables phosphate ion binding ISO
Inferred from Sequence Orthology
more info
  
enables phosphoprotein phosphatase activity ISO
Inferred from Sequence Orthology
more info
 PubMed 
enables protein tyrosine phosphatase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein tyrosine phosphatase activity ISO
Inferred from Sequence Orthology
more info
  
enables protein-containing complex binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables receptor tyrosine kinase binding ISO
Inferred from Sequence Orthology
more info
  
enables transmembrane receptor protein tyrosine phosphatase activity ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within cell adhesion IEA
Inferred from Electronic Annotation
more info
  
involved_in cell migration ISO
Inferred from Sequence Orthology
more info
  
involved_in dephosphorylation IEA
Inferred from Electronic Annotation
more info
  
involved_in homophilic cell adhesion via plasma membrane adhesion molecules ISO
Inferred from Sequence Orthology
more info
  
involved_in negative regulation of cell population proliferation ISO
Inferred from Sequence Orthology
more info
  
involved_in negative regulation of cell projection organization ISO
Inferred from Sequence Orthology
more info
  
involved_in negative regulation of cytokine-mediated signaling pathway ISO
Inferred from Sequence Orthology
more info
  
involved_in negative regulation of epidermal growth factor receptor signaling pathway ISO
Inferred from Sequence Orthology
more info
  
involved_in negative regulation of insulin receptor signaling pathway ISO
Inferred from Sequence Orthology
more info
  
involved_in negative regulation of neurotrophin TRK receptor signaling pathway ISO
Inferred from Sequence Orthology
more info
  
involved_in negative regulation of receptor binding ISO
Inferred from Sequence Orthology
more info
  
involved_in nervous system development ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within neuron projection regeneration IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in peptidyl-tyrosine dephosphorylation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in peptidyl-tyrosine dephosphorylation ISO
Inferred from Sequence Orthology
more info
  
involved_in positive regulation of apoptotic process ISO
Inferred from Sequence Orthology
more info
  
involved_in positive regulation of dendrite morphogenesis ISO
Inferred from Sequence Orthology
more info
  
involved_in positive regulation of neuron apoptotic process ISO
Inferred from Sequence Orthology
more info
  
involved_in protein dephosphorylation IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within regulation of axon regeneration IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within regulation of neuron projection development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of postsynapse organization ISO
Inferred from Sequence Orthology
more info
  
involved_in regulation of synapse structure or activity ISO
Inferred from Sequence Orthology
more info
  
involved_in synaptic membrane adhesion IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in synaptic membrane adhesion ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
located_in endosome ISO
Inferred from Sequence Orthology
more info
  
located_in excitatory synapse ISO
Inferred from Sequence Orthology
more info
  
located_in growth cone ISO
Inferred from Sequence Orthology
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in neuron projection IDA
Inferred from Direct Assay
more info
 PubMed 
located_in neuronal cell body IDA
Inferred from Direct Assay
more info
 PubMed 
located_in neuronal cell body ISO
Inferred from Sequence Orthology
more info
  
is_active_in postsynaptic density membrane ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
receptor-type tyrosine-protein phosphatase F
Names
leukocyte antigen-related (LAR) PTP receptor
leukocyte common antigen related
NP_035343.2
XP_006502927.1
XP_006502928.1
XP_006502929.1
XP_006502930.1
XP_006502931.1
XP_006502932.1
XP_006502933.1
XP_006502934.1
XP_006502935.1
XP_006502937.1
XP_006502938.1
XP_006502939.1
XP_030109220.1
XP_030109221.1
XP_030109222.1
XP_030109223.1
XP_036019772.1
XP_036019773.1
XP_036019774.1
XP_036019775.1
XP_036019776.1
XP_036019777.1
XP_036019778.1
XP_036019779.1
XP_036019780.1
XP_036019781.1
XP_036019782.1
XP_036019783.1
XP_036019784.1
XP_036019785.1
XP_036019786.1
XP_036019787.1
XP_036019788.1
XP_036019789.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_011213.2 → NP_035343.2  receptor-type tyrosine-protein phosphatase F precursor

    See identical proteins and their annotated locations for NP_035343.2

    Status: VALIDATED

    Source sequence(s)
    AI385919, AK133085, AL626764, AL807774, BU055092, BU056582, CA315396, CD352108, CK634962, CV556730, CX201972
    Consensus CDS
    CCDS18546.1
    UniProtKB/Swiss-Prot
    A2A8L5, Q6PG86, Q9EQ17
    Related
    ENSMUSP00000039368.7, ENSMUST00000049074.13
    Conserved Domains (9) summary
    cd00096
    Location:50 → 121
    Ig; Immunoglobulin domain
    cd05738
    Location:152 → 226
    Ig2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    cd05739
    Location:246 → 314
    Ig3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    smart00194
    Location:1342 → 1597
    PTPc; Protein tyrosine phosphatase, catalytic domain
    smart00410
    Location:141 → 225
    IG_like; Immunoglobulin like
    cd00047
    Location:1368 → 1597
    PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
    cd00063
    Location:319 → 408
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:33 → 124
    I-set; Immunoglobulin I-set domain
    pfam00041
    Location:910 → 991
    fn3; Fibronectin type III domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    118065410..118148602 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030253363.1 → XP_030109223.1  receptor-type tyrosine-protein phosphatase F isoform X30

    Conserved Domains (6) summary
    cd05739
    Location:246 → 314
    Ig3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    cd00063
    Location:319 → 408
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd05738
    Location:152 → 226
    Ig2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    cd14629
    Location:1308 → 1598
    R-PTP-F-2; PTP-like domain of receptor-type tyrosine-protein phosphatase F, repeat 2
    pfam07679
    Location:33 → 124
    I-set; Immunoglobulin I-set domain
    cl28904
    Location:1031 → 1306
    PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily

  2. XM_006502872.2 → XP_006502935.1  receptor-type tyrosine-protein phosphatase F isoform X15

    Conserved Domains (6) summary
    cd05739
    Location:246 → 314
    Ig3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    cd00063
    Location:319 → 408
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd05738
    Location:152 → 226
    Ig2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    cd14629
    Location:1501 → 1791
    R-PTP-F-2; PTP-like domain of receptor-type tyrosine-protein phosphatase F, repeat 2
    pfam07679
    Location:33 → 124
    I-set; Immunoglobulin I-set domain
    cl28904
    Location:1224 → 1499
    PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily

  3. XM_030253360.1 → XP_030109220.1  receptor-type tyrosine-protein phosphatase F isoform X12

    Conserved Domains (6) summary
    cd05739
    Location:246 → 314
    Ig3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    cd00063
    Location:319 → 408
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd05738
    Location:152 → 226
    Ig2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    cd14629
    Location:1512 → 1802
    R-PTP-F-2; PTP-like domain of receptor-type tyrosine-protein phosphatase F, repeat 2
    pfam07679
    Location:33 → 124
    I-set; Immunoglobulin I-set domain
    cl28904
    Location:1235 → 1510
    PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily

  4. XM_036163892.1 → XP_036019785.1  receptor-type tyrosine-protein phosphatase F isoform X29

    Conserved Domains (7) summary
    cd00063
    Location:319 → 408
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd14629
    Location:1317 → 1607
    R-PTP-F-2; PTP-like domain of receptor-type tyrosine-protein phosphatase F, repeat 2
    pfam07679
    Location:33 → 124
    I-set; Immunoglobulin I-set domain
    cd00096
    Location:33 → 36
    Ig; Ig strand A [structural motif]
    cd05738
    Location:136 → 226
    IgI_2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F; member of the I-set of IgSF domains
    cd05739
    Location:235 → 316
    IgI_3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F (also known as LAR), type IIa; member of the I-set of IgSF domains
    cl28904
    Location:1040 → 1315
    PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily

  5. XM_030253362.1 → XP_030109222.1  receptor-type tyrosine-protein phosphatase F isoform X27

    Conserved Domains (6) summary
    cd05739
    Location:246 → 314
    Ig3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    cd00063
    Location:319 → 408
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd05738
    Location:152 → 226
    Ig2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    cd14629
    Location:1328 → 1618
    R-PTP-F-2; PTP-like domain of receptor-type tyrosine-protein phosphatase F, repeat 2
    pfam07679
    Location:33 → 124
    I-set; Immunoglobulin I-set domain
    cl28904
    Location:1051 → 1326
    PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily

  6. XM_036163881.1 → XP_036019774.1  receptor-type tyrosine-protein phosphatase F isoform X13

    Conserved Domains (7) summary
    cd00063
    Location:319 → 408
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd14629
    Location:1510 → 1800
    R-PTP-F-2; PTP-like domain of receptor-type tyrosine-protein phosphatase F, repeat 2
    pfam07679
    Location:33 → 124
    I-set; Immunoglobulin I-set domain
    cd00096
    Location:33 → 36
    Ig; Ig strand A [structural motif]
    cd05738
    Location:136 → 226
    IgI_2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F; member of the I-set of IgSF domains
    cd05739
    Location:235 → 316
    IgI_3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F (also known as LAR), type IIa; member of the I-set of IgSF domains
    cl28904
    Location:1233 → 1508
    PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily

  7. XM_030253361.2 → XP_030109221.1  receptor-type tyrosine-protein phosphatase F isoform X9

    Conserved Domains (6) summary
    cd05739
    Location:246 → 314
    Ig3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    cd00063
    Location:319 → 408
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd05738
    Location:152 → 226
    Ig2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    cd14629
    Location:1521 → 1811
    R-PTP-F-2; PTP-like domain of receptor-type tyrosine-protein phosphatase F, repeat 2
    pfam07679
    Location:33 → 124
    I-set; Immunoglobulin I-set domain
    cl28904
    Location:1244 → 1519
    PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily

  8. XM_036163889.1 → XP_036019782.1  receptor-type tyrosine-protein phosphatase F isoform X24

    Conserved Domains (7) summary
    cd00063
    Location:319 → 408
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd14629
    Location:1410 → 1700
    R-PTP-F-2; PTP-like domain of receptor-type tyrosine-protein phosphatase F, repeat 2
    pfam07679
    Location:33 → 124
    I-set; Immunoglobulin I-set domain
    cd00096
    Location:33 → 36
    Ig; Ig strand A [structural motif]
    cd05738
    Location:136 → 226
    IgI_2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F; member of the I-set of IgSF domains
    cd05739
    Location:235 → 316
    IgI_3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F (also known as LAR), type IIa; member of the I-set of IgSF domains
    cl28904
    Location:1133 → 1408
    PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily

  9. XM_036163886.1 → XP_036019779.1  receptor-type tyrosine-protein phosphatase F isoform X21

    Conserved Domains (7) summary
    cd00063
    Location:319 → 408
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd14629
    Location:1421 → 1711
    R-PTP-F-2; PTP-like domain of receptor-type tyrosine-protein phosphatase F, repeat 2
    pfam07679
    Location:33 → 124
    I-set; Immunoglobulin I-set domain
    cd00096
    Location:33 → 36
    Ig; Ig strand A [structural motif]
    cd05738
    Location:136 → 226
    IgI_2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F; member of the I-set of IgSF domains
    cd05739
    Location:235 → 316
    IgI_3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F (also known as LAR), type IIa; member of the I-set of IgSF domains
    cl28904
    Location:1144 → 1419
    PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily

  10. XM_006502868.2 → XP_006502931.1  receptor-type tyrosine-protein phosphatase F isoform X5

    Conserved Domains (6) summary
    cd05739
    Location:246 → 314
    Ig3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    cd00063
    Location:319 → 408
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd05738
    Location:152 → 226
    Ig2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    cd14629
    Location:1614 → 1904
    R-PTP-F-2; PTP-like domain of receptor-type tyrosine-protein phosphatase F, repeat 2
    pfam07679
    Location:33 → 124
    I-set; Immunoglobulin I-set domain
    cl28904
    Location:1337 → 1612
    PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily

  11. XM_036163887.1 → XP_036019780.1  receptor-type tyrosine-protein phosphatase F isoform X22

    Conserved Domains (7) summary
    cd00063
    Location:319 → 408
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd14629
    Location:1419 → 1709
    R-PTP-F-2; PTP-like domain of receptor-type tyrosine-protein phosphatase F, repeat 2
    pfam07679
    Location:33 → 124
    I-set; Immunoglobulin I-set domain
    cd00096
    Location:33 → 36
    Ig; Ig strand A [structural motif]
    cd05738
    Location:136 → 226
    IgI_2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F; member of the I-set of IgSF domains
    cd05739
    Location:235 → 316
    IgI_3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F (also known as LAR), type IIa; member of the I-set of IgSF domains
    cl28904
    Location:1142 → 1417
    PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily

  12. XM_036163884.1 → XP_036019777.1  receptor-type tyrosine-protein phosphatase F isoform X18

    Conserved Domains (7) summary
    cd00063
    Location:319 → 408
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd14629
    Location:1430 → 1720
    R-PTP-F-2; PTP-like domain of receptor-type tyrosine-protein phosphatase F, repeat 2
    pfam07679
    Location:33 → 124
    I-set; Immunoglobulin I-set domain
    cd00096
    Location:33 → 36
    Ig; Ig strand A [structural motif]
    cd05738
    Location:136 → 226
    IgI_2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F; member of the I-set of IgSF domains
    cd05739
    Location:235 → 316
    IgI_3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F (also known as LAR), type IIa; member of the I-set of IgSF domains
    cl28904
    Location:1153 → 1428
    PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily

  13. XM_006502869.2 → XP_006502932.1  receptor-type tyrosine-protein phosphatase F isoform X6

    Conserved Domains (6) summary
    cd05739
    Location:246 → 314
    Ig3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    cd00063
    Location:319 → 408
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd05738
    Location:152 → 226
    Ig2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    cd14629
    Location:1612 → 1902
    R-PTP-F-2; PTP-like domain of receptor-type tyrosine-protein phosphatase F, repeat 2
    pfam07679
    Location:33 → 124
    I-set; Immunoglobulin I-set domain
    cl28904
    Location:1335 → 1610
    PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily

  14. XM_006502865.2 → XP_006502928.1  receptor-type tyrosine-protein phosphatase F isoform X2

    Conserved Domains (6) summary
    cd05739
    Location:246 → 314
    Ig3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    cd00063
    Location:319 → 408
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd05738
    Location:152 → 226
    Ig2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    cd14629
    Location:1623 → 1913
    R-PTP-F-2; PTP-like domain of receptor-type tyrosine-protein phosphatase F, repeat 2
    pfam07679
    Location:33 → 124
    I-set; Immunoglobulin I-set domain
    cl28904
    Location:1346 → 1621
    PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily

  15. XM_036163882.1 → XP_036019775.1  receptor-type tyrosine-protein phosphatase F isoform X14

    Conserved Domains (7) summary
    cd00063
    Location:325 → 414
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd14629
    Location:1507 → 1797
    R-PTP-F-2; PTP-like domain of receptor-type tyrosine-protein phosphatase F, repeat 2
    pfam07679
    Location:33 → 124
    I-set; Immunoglobulin I-set domain
    cd00096
    Location:33 → 36
    Ig; Ig strand A [structural motif]
    cd05738
    Location:136 → 232
    IgI_2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F; member of the I-set of IgSF domains
    cd05739
    Location:241 → 322
    IgI_3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F (also known as LAR), type IIa; member of the I-set of IgSF domains
    cl28904
    Location:1230 → 1505
    PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily

  16. XM_036163879.1 → XP_036019772.1  receptor-type tyrosine-protein phosphatase F isoform X10

    Conserved Domains (7) summary
    cd00063
    Location:325 → 414
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd14629
    Location:1518 → 1808
    R-PTP-F-2; PTP-like domain of receptor-type tyrosine-protein phosphatase F, repeat 2
    pfam07679
    Location:33 → 124
    I-set; Immunoglobulin I-set domain
    cd00096
    Location:33 → 36
    Ig; Ig strand A [structural motif]
    cd05738
    Location:136 → 232
    IgI_2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F; member of the I-set of IgSF domains
    cd05739
    Location:241 → 322
    IgI_3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F (also known as LAR), type IIa; member of the I-set of IgSF domains
    cl28904
    Location:1241 → 1516
    PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily

  17. XM_036163891.1 → XP_036019784.1  receptor-type tyrosine-protein phosphatase F isoform X28

    Conserved Domains (7) summary
    cd00063
    Location:325 → 414
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd14629
    Location:1323 → 1613
    R-PTP-F-2; PTP-like domain of receptor-type tyrosine-protein phosphatase F, repeat 2
    pfam07679
    Location:33 → 124
    I-set; Immunoglobulin I-set domain
    cd00096
    Location:33 → 36
    Ig; Ig strand A [structural motif]
    cd05738
    Location:136 → 232
    IgI_2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F; member of the I-set of IgSF domains
    cd05739
    Location:241 → 322
    IgI_3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F (also known as LAR), type IIa; member of the I-set of IgSF domains
    cl28904
    Location:1046 → 1321
    PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily

  18. XM_006502876.2 → XP_006502939.1  receptor-type tyrosine-protein phosphatase F isoform X26

    Conserved Domains (6) summary
    cd05739
    Location:252 → 320
    Ig3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    cd00063
    Location:325 → 414
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd05738
    Location:152 → 232
    Ig2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    cd14629
    Location:1334 → 1624
    R-PTP-F-2; PTP-like domain of receptor-type tyrosine-protein phosphatase F, repeat 2
    pfam07679
    Location:33 → 124
    I-set; Immunoglobulin I-set domain
    cl28904
    Location:1057 → 1332
    PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily

  19. XM_036163880.1 → XP_036019773.1  receptor-type tyrosine-protein phosphatase F isoform X11

    Conserved Domains (7) summary
    cd00063
    Location:325 → 414
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd14629
    Location:1516 → 1806
    R-PTP-F-2; PTP-like domain of receptor-type tyrosine-protein phosphatase F, repeat 2
    pfam07679
    Location:33 → 124
    I-set; Immunoglobulin I-set domain
    cd00096
    Location:33 → 36
    Ig; Ig strand A [structural motif]
    cd05738
    Location:136 → 232
    IgI_2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F; member of the I-set of IgSF domains
    cd05739
    Location:241 → 322
    IgI_3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F (also known as LAR), type IIa; member of the I-set of IgSF domains
    cl28904
    Location:1239 → 1514
    PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily

  20. XM_006502871.2 → XP_006502934.1  receptor-type tyrosine-protein phosphatase F isoform X8

    Conserved Domains (6) summary
    cd05739
    Location:252 → 320
    Ig3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    cd00063
    Location:325 → 414
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd05738
    Location:152 → 232
    Ig2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    cd14629
    Location:1527 → 1817
    R-PTP-F-2; PTP-like domain of receptor-type tyrosine-protein phosphatase F, repeat 2
    pfam07679
    Location:33 → 124
    I-set; Immunoglobulin I-set domain
    cl28904
    Location:1250 → 1525
    PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily

  21. XM_036163888.1 → XP_036019781.1  receptor-type tyrosine-protein phosphatase F isoform X23

    Conserved Domains (7) summary
    cd00063
    Location:325 → 414
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd14629
    Location:1416 → 1706
    R-PTP-F-2; PTP-like domain of receptor-type tyrosine-protein phosphatase F, repeat 2
    pfam07679
    Location:33 → 124
    I-set; Immunoglobulin I-set domain
    cd00096
    Location:33 → 36
    Ig; Ig strand A [structural motif]
    cd05738
    Location:136 → 232
    IgI_2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F; member of the I-set of IgSF domains
    cd05739
    Location:241 → 322
    IgI_3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F (also known as LAR), type IIa; member of the I-set of IgSF domains
    cl28904
    Location:1139 → 1414
    PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily

  22. XM_006502875.2 → XP_006502938.1  receptor-type tyrosine-protein phosphatase F isoform X19

    Conserved Domains (6) summary
    cd05739
    Location:252 → 320
    Ig3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    cd00063
    Location:325 → 414
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd05738
    Location:152 → 232
    Ig2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    cd14629
    Location:1427 → 1717
    R-PTP-F-2; PTP-like domain of receptor-type tyrosine-protein phosphatase F, repeat 2
    pfam07679
    Location:33 → 124
    I-set; Immunoglobulin I-set domain
    cl28904
    Location:1150 → 1425
    PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily

  23. XM_006502870.2 → XP_006502933.1  receptor-type tyrosine-protein phosphatase F isoform X7

    Conserved Domains (6) summary
    cd05739
    Location:252 → 320
    Ig3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    cd00063
    Location:325 → 414
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd05738
    Location:152 → 232
    Ig2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    cd14629
    Location:1609 → 1899
    R-PTP-F-2; PTP-like domain of receptor-type tyrosine-protein phosphatase F, repeat 2
    pfam07679
    Location:33 → 124
    I-set; Immunoglobulin I-set domain
    cl28904
    Location:1332 → 1607
    PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily

  24. XM_006502866.2 → XP_006502929.1  receptor-type tyrosine-protein phosphatase F isoform X3

    Conserved Domains (6) summary
    cd05739
    Location:252 → 320
    Ig3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    cd00063
    Location:325 → 414
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd05738
    Location:152 → 232
    Ig2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    cd14629
    Location:1620 → 1910
    R-PTP-F-2; PTP-like domain of receptor-type tyrosine-protein phosphatase F, repeat 2
    pfam07679
    Location:33 → 124
    I-set; Immunoglobulin I-set domain
    cl28904
    Location:1343 → 1618
    PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily

  25. XM_036163885.1 → XP_036019778.1  receptor-type tyrosine-protein phosphatase F isoform X20

    Conserved Domains (7) summary
    cd00063
    Location:325 → 414
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd14629
    Location:1425 → 1715
    R-PTP-F-2; PTP-like domain of receptor-type tyrosine-protein phosphatase F, repeat 2
    pfam07679
    Location:33 → 124
    I-set; Immunoglobulin I-set domain
    cd00096
    Location:33 → 36
    Ig; Ig strand A [structural motif]
    cd05738
    Location:136 → 232
    IgI_2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F; member of the I-set of IgSF domains
    cd05739
    Location:241 → 322
    IgI_3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F (also known as LAR), type IIa; member of the I-set of IgSF domains
    cl28904
    Location:1148 → 1423
    PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily

  26. XM_006502874.2 → XP_006502937.1  receptor-type tyrosine-protein phosphatase F isoform X17

    Conserved Domains (6) summary
    cd05739
    Location:252 → 320
    Ig3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    cd00063
    Location:325 → 414
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd05738
    Location:152 → 232
    Ig2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    cd14629
    Location:1436 → 1726
    R-PTP-F-2; PTP-like domain of receptor-type tyrosine-protein phosphatase F, repeat 2
    pfam07679
    Location:33 → 124
    I-set; Immunoglobulin I-set domain
    cl28904
    Location:1159 → 1434
    PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily

  27. XM_006502867.2 → XP_006502930.1  receptor-type tyrosine-protein phosphatase F isoform X4

    Conserved Domains (6) summary
    cd05739
    Location:252 → 320
    Ig3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    cd00063
    Location:325 → 414
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd05738
    Location:152 → 232
    Ig2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    cd14629
    Location:1618 → 1908
    R-PTP-F-2; PTP-like domain of receptor-type tyrosine-protein phosphatase F, repeat 2
    pfam07679
    Location:33 → 124
    I-set; Immunoglobulin I-set domain
    cl28904
    Location:1341 → 1616
    PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily

  28. XM_006502864.2 → XP_006502927.1  receptor-type tyrosine-protein phosphatase F isoform X1

    Conserved Domains (6) summary
    cd05739
    Location:252 → 320
    Ig3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    cd00063
    Location:325 → 414
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd05738
    Location:152 → 232
    Ig2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    cd14629
    Location:1629 → 1919
    R-PTP-F-2; PTP-like domain of receptor-type tyrosine-protein phosphatase F, repeat 2
    pfam07679
    Location:33 → 124
    I-set; Immunoglobulin I-set domain
    cl28904
    Location:1352 → 1627
    PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily

  29. XM_036163890.1 → XP_036019783.1  receptor-type tyrosine-protein phosphatase F isoform X25

    Conserved Domains (5) summary
    cd00063
    Location:167 → 256
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd14629
    Location:1358 → 1648
    R-PTP-F-2; PTP-like domain of receptor-type tyrosine-protein phosphatase F, repeat 2
    pfam00041
    Location:665 → 746
    fn3; Fibronectin type III domain
    cd05739
    Location:83 → 164
    IgI_3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F (also known as LAR), type IIa; member of the I-set of IgSF domains
    cl28904
    Location:1081 → 1356
    PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily

  30. XM_036163883.1 → XP_036019776.1  receptor-type tyrosine-protein phosphatase F isoform X16

    Conserved Domains (5) summary
    cd00063
    Location:167 → 256
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd14629
    Location:1471 → 1761
    R-PTP-F-2; PTP-like domain of receptor-type tyrosine-protein phosphatase F, repeat 2
    pfam00041
    Location:767 → 848
    fn3; Fibronectin type III domain
    cd05739
    Location:83 → 164
    IgI_3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F (also known as LAR), type IIa; member of the I-set of IgSF domains
    cl28904
    Location:1194 → 1469
    PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily

  31. XM_036163896.1 → XP_036019789.1  receptor-type tyrosine-protein phosphatase F isoform X34

    UniProtKB/TrEMBL
    F6Y3V0
    Conserved Domains (4) summary
    cd00063
    Location:167 → 256
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd14629
    Location:1165 → 1455
    R-PTP-F-2; PTP-like domain of receptor-type tyrosine-protein phosphatase F, repeat 2
    cd05739
    Location:83 → 164
    IgI_3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F (also known as LAR), type IIa; member of the I-set of IgSF domains
    cl28904
    Location:888 → 1163
    PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily

  32. XM_036163895.1 → XP_036019788.1  receptor-type tyrosine-protein phosphatase F isoform X33

    UniProtKB/TrEMBL
    F6Y3V0
    Related
    ENSMUSP00000117313.2, ENSMUST00000150096.8
    Conserved Domains (4) summary
    cd00063
    Location:167 → 256
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd14629
    Location:1176 → 1466
    R-PTP-F-2; PTP-like domain of receptor-type tyrosine-protein phosphatase F, repeat 2
    cd05739
    Location:83 → 164
    IgI_3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F (also known as LAR), type IIa; member of the I-set of IgSF domains
    cl28904
    Location:899 → 1174
    PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily

  33. XM_036163893.1 → XP_036019786.1  receptor-type tyrosine-protein phosphatase F isoform X31

    Related
    ENSMUSP00000119954.2, ENSMUST00000124758.2
    Conserved Domains (5) summary
    cd00063
    Location:167 → 256
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd14629
    Location:1369 → 1659
    R-PTP-F-2; PTP-like domain of receptor-type tyrosine-protein phosphatase F, repeat 2
    pfam00041
    Location:665 → 746
    fn3; Fibronectin type III domain
    cd05739
    Location:83 → 164
    IgI_3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F (also known as LAR), type IIa; member of the I-set of IgSF domains
    cl28904
    Location:1092 → 1367
    PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily

  34. XM_036163894.1 → XP_036019787.1  receptor-type tyrosine-protein phosphatase F isoform X32

    UniProtKB/TrEMBL
    F6Y3V0
    Conserved Domains (5) summary
    cd00063
    Location:167 → 256
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd14629
    Location:1267 → 1557
    R-PTP-F-2; PTP-like domain of receptor-type tyrosine-protein phosphatase F, repeat 2
    pfam00041
    Location:457 → 544
    fn3; Fibronectin type III domain
    cd05739
    Location:83 → 164
    IgI_3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F (also known as LAR), type IIa; member of the I-set of IgSF domains
    cl28904
    Location:990 → 1265
    PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A2A8L5.1 GenPept UniProtKB/Swiss-Prot:A2A8L5

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