U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

u2af1 U2 small nuclear RNA auxiliary factor 1 [ Danio rerio (zebrafish) ]

Gene ID: 192328, updated on 27-Mar-2024

Summary

Go to the top of the page Help
Official Symbol
u2af1provided by ZNC
Official Full Name
U2 small nuclear RNA auxiliary factor 1provided by ZNC
Primary source
ZFIN:ZDB-GENE-020419-1
See related
Ensembl:ENSDARG00000015325 AllianceGenome:ZFIN:ZDB-GENE-020419-1
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
CHUNP6860; zgc:111896
Summary
Predicted to enable pre-mRNA 3'-splice site binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be part of U2AF complex and spliceosomal complex. Orthologous to human U2AF1 (U2 small nuclear RNA auxiliary factor 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
chromosome: 9
Exon count:
8
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 9 NC_007120.7 (9230448..9242690, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 9 NC_007120.6 (9252411..9264653, complement)

Chromosome 9 - NC_007120.7Genomic Context describing neighboring genes Neighboring gene salt-inducible kinase 1 Neighboring gene cystathionine beta-synthase b Neighboring gene si:ch211-214p13.3 Neighboring gene uncharacterized LOC101884846

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. p53 upregulation is a frequent response to deficiency of cell-essential genes. Danilova N, et al. PLoS One, 2010 Dec 31. PMID 21209837, Free PMC Article
  2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  5. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

Go to the top of the page

General gene information

Go to the top of the page Help

Homology

Clone Names

  • MGC111896

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
  
enables pre-mRNA 3'-splice site binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in mRNA splicing, via spliceosome IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within mRNA splicing, via spliceosome IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of U2AF complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of U2AF complex IEA
Inferred from Electronic Annotation
more info
  
part_of spliceosomal complex IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

Go to the top of the page Help
Preferred Names
splicing factor U2AF 35 kDa subunit
Names
U2(RNU2) small nuclear RNA auxiliary factor 1
U2(RNU2) small nuclear RNA auxillary factor 1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_177479.2 → NP_803432.1  splicing factor U2AF 35 kDa subunit

    See identical proteins and their annotated locations for NP_803432.1

    Status: PROVISIONAL

    Source sequence(s)
    AF506202
    UniProtKB/TrEMBL
    Q8JHJ3
    Related
    ENSDARP00000005582.5, ENSDART00000021191.6
    Conserved Domains (2) summary
    cd12538
    Location:43 → 145
    RRM_U2AF35; RNA recognition motif in U2 small nuclear ribonucleoprotein auxiliary factor U2AF 35 kDa subunit (U2AF35)
    pfam00642
    Location:148 → 174
    zf-CCCH; Zinc finger C-x8-C-x5-C-x3-H type (and similar)

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007120.7 Reference GRCz11 Primary Assembly

    Range
    9230448..9242690 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools
Miscellaneous