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Or7a42 olfactory receptor family 7 subfamily A member 42 [ Mus musculus (house mouse) ]

Gene ID: 18372, updated on 11-Apr-2024

Summary

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Official Symbol
Or7a42provided by MGI
Official Full Name
olfactory receptor family 7 subfamily A member 42provided by MGI
Primary source
MGI:MGI:107174
See related
Ensembl:ENSMUSG00000094080 AllianceGenome:MGI:107174
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Olfr8; MOR139-5P; GA_x5J8B7TNKDU-1250-1574
Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
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Genomic context

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Location:
10 C1; 10 39.72 cM
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (78791041..78791973)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (78955207..78956139)

Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 7 subfamily A member 39 Neighboring gene STARR-seq mESC enhancer starr_27236 Neighboring gene olfactory receptor family 7 subfamily A member 38 Neighboring gene STARR-seq mESC enhancer starr_27237 Neighboring gene olfactory receptor family 7 subfamily A member 37 Neighboring gene olfactory receptor family 7 subfamily A member 36

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Information coding in the olfactory system: evidence for a stereotyped and highly organized epitope map in the olfactory bulb. Ressler KJ, et al. Cell, 1994 Dec 30. PMID 7528109
  2. Olfactory receptors and signalling elements in the Grueneberg ganglion. Fleischer J, et al. J Neurochem, 2006 Jul. PMID 16805845
  3. Evolution of odorant receptors expressed in mammalian testes. Branscomb A, et al. Genetics, 2000 Oct. PMID 11014824, Free PMC Article
  4. The olfactory receptor gene repertoire in primates and mouse: evidence for reduction of the functional fraction in primates. Rouquier S, et al. Proc Natl Acad Sci U S A, 2000 Mar 14. PMID 10706615, Free PMC Article
  5. The chromosomal distribution of mouse odorant receptor genes. Sullivan SL, et al. Proc Natl Acad Sci U S A, 1996 Jan 23. PMID 8570653, Free PMC Article

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
  
enables olfactory receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables olfactory receptor activity ISA
Inferred from Sequence Alignment
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within G protein-coupled receptor signaling pathway ISA
Inferred from Sequence Alignment
more info
 PubMed 
acts_upstream_of_or_within response to stimulus IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within sensory perception of smell ISA
Inferred from Sequence Alignment
more info
 PubMed 
involved_in signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in membrane ISA
Inferred from Sequence Alignment
more info
 PubMed 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
olfactory receptor 7A42
Names
GA_x6K02T2QGN0-2857086-2856154
odorant receptor M64
olfactory receptor 8
olfactory receptor GA_x5J8B7TNKDU-1250-1574

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_207201.1 → NP_997084.1  olfactory receptor 7A42

    See identical proteins and their annotated locations for NP_997084.1

    Status: PROVISIONAL

    Source sequence(s)
    AY318562
    Consensus CDS
    CCDS23971.1
    UniProtKB/Swiss-Prot
    Q60892, Q7TQV0, Q9ERY5, Q9JM18
    UniProtKB/TrEMBL
    Q9JHW3
    Related
    ENSMUSP00000080282.2, ENSMUST00000081571.2
    Conserved Domains (2) summary
    pfam00001
    Location:42 → 291
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    cl21561
    Location:32 → 309
    7tm_4; Olfactory receptor

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000076.7 Reference GRCm39 C57BL/6J

    Range
    78791041..78791973
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NG_001635.2: Suppressed sequence

    Description
    NG_001635.2: This RefSeq was permanently suppressed because it is now thought that this gene does encode a protein.
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q60892.2 GenPept UniProtKB/Swiss-Prot:Q60892

Gene LinkOut

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