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Or6z7 olfactory receptor family 6 subfamily Z member 7 [ Mus musculus (house mouse) ]

Gene ID: 18349, updated on 8-Feb-2024

Summary

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Official Symbol
Or6z7provided by MGI
Official Full Name
olfactory receptor family 6 subfamily Z member 7provided by MGI
Primary source
MGI:MGI:106685
See related
Ensembl:ENSMUSG00000096228 AllianceGenome:MGI:106685
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Olfr5; ORL120; MOR103-8
Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Expression
Low expression observed in reference dataset See more
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Genomic context

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See Or6z7 in Genome Data Viewer
Location:
7 A1; 7 3.76 cM
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (6483215..6490013, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (6480216..6487014, complement)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 6 subfamily Z member 3 Neighboring gene olfactory receptor family 6 subfamily Z member 5 Neighboring gene STARR-seq mESC enhancer starr_17980 Neighboring gene olfactory receptor family 6 subfamily Z member 6 Neighboring gene olfactory receptor family 6 subfamily Z member 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Information coding in the olfactory system: evidence for a stereotyped and highly organized epitope map in the olfactory bulb. Ressler KJ, et al. Cell, 1994 Dec 30. PMID 7528109
  2. The chromosomal distribution of mouse odorant receptor genes. Sullivan SL, et al. Proc Natl Acad Sci U S A, 1996 Jan 23. PMID 8570653, Free PMC Article
  3. The olfactory receptor gene superfamily of the mouse. Zhang X, et al. Nat Neurosci, 2002 Feb. PMID 11802173
  4. Different evolutionary processes shaped the mouse and human olfactory receptor gene families. Young JM, et al. Hum Mol Genet, 2002 Mar 1. PMID 11875048
  5. Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels. Young JM, et al. Genome Biol, 2003. PMID 14611657, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Clone Names

  • MGC123608

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
  
enables olfactory receptor activity ISA
Inferred from Sequence Alignment
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within G protein-coupled receptor signaling pathway ISA
Inferred from Sequence Alignment
more info
 PubMed 
acts_upstream_of_or_within detection of chemical stimulus involved in sensory perception of smell ISA
Inferred from Sequence Alignment
more info
 PubMed 
acts_upstream_of_or_within response to stimulus IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within sensory perception of smell ISA
Inferred from Sequence Alignment
more info
 PubMed 
acts_upstream_of_or_within signal transduction IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane ISA
Inferred from Sequence Alignment
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
olfactory receptor 6Z7
Names
GA_x6K02T2QGBW-3210997-3210059
odorant receptor M41
olfactory receptor 103-8
olfactory receptor 5

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_146914.2 → NP_667125.1  olfactory receptor 6Z7

    See identical proteins and their annotated locations for NP_667125.1

    Status: VALIDATED

    Source sequence(s)
    AC188461
    Consensus CDS
    CCDS57479.1
    UniProtKB/Swiss-Prot
    Q3MI75, Q60889, Q8VGH4
    Related
    ENSMUSP00000083498.5, ENSMUST00000086318.5
    Conserved Domains (1) summary
    cd15224
    Location:30 → 298
    7tmA_OR6B-like; olfactory receptor subfamily 6B and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    6483215..6490013 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011250453.3 → XP_011248755.1  olfactory receptor 6Z7 isoform X1

    See identical proteins and their annotated locations for XP_011248755.1

    UniProtKB/Swiss-Prot
    Q3MI75, Q60889, Q8VGH4
    Related
    ENSMUSP00000147586.3, ENSMUST00000209866.4
    Conserved Domains (1) summary
    cd15224
    Location:30 → 298
    7tmA_OR6B-like; olfactory receptor subfamily 6B and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q60889.2 GenPept UniProtKB/Swiss-Prot:Q60889

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