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ugt-50 Putative UDP-glucuronosyltransferase ugt-50;UDP-glucuronosyltransferase;glucuronosyltransferase [ Caenorhabditis elegans ]

Gene ID: 181413, updated on 23-Nov-2023

Summary

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Gene symbol
ugt-50
Gene description
Putative UDP-glucuronosyltransferase ugt-50;UDP-glucuronosyltransferase;glucuronosyltransferase
Primary source
WormBase:WBGene00011564
Locus tag
CELE_T07C5.1
See related
AllianceGenome:WB:WBGene00011564
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable UDP-glycosyltransferase activity. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in intracellular membrane-bounded organelle. Is expressed in PVQ; intestine; and lateral ganglion. Orthologous to human UGT2B7 (UDP glucuronosyltransferase family 2 member B7). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
chromosome: X
Exon count:
10
Sequence:
Chromosome: X; NC_003284.9 (12691573..12695652)

Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene A disintegrin and metalloproteinase with thrombospondin motifs adt-1;Peptidase M12B domain-containing protein Neighboring gene ncRNA Neighboring gene Nuclear receptor domain-containing protein Neighboring gene pseudo Neighboring gene Nuclear Hormone Receptor family Neighboring gene Nuclear Hormone Receptor family

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003284.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A starvation-induced noncoding RNA modulates expression of Dicer-regulated genes. Hellwig S, et al. Proc Natl Acad Sci U S A, 2008 Sep 2. PMID 18723671, Free PMC Article
  2. Identification of CED-3 substrates by a yeast-based screening method. Kim SY, et al. Mol Biotechnol, 2004 May. PMID 15122042
  3. UDP-glycosyltransferase family in Haemonchus contortus: Phylogenetic analysis, constitutive expression, sex-differences and resistance-related differences. Matoušková P, et al. Int J Parasitol Drugs Drug Resist, 2018 Dec. PMID 30293057, Free PMC Article
  4. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
  5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables UDP-glycosyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables UDP-glycosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables glucuronosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables glycosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Putative UDP-glucuronosyltransferase ugt-50;UDP-glucuronosyltransferase;glucuronosyltransferase
NP_001300379.1
  • Confirmed by transcript evidence
NP_001300380.1
  • Confirmed by transcript evidence
NP_001359531.1
  • Confirmed by transcript evidence
NP_741913.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003284.9 Reference assembly

    Range
    12691573..12695652
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001373541.1 → NP_001359531.1  Putative UDP-glucuronosyltransferase ugt-50 [Caenorhabditis elegans]

    Status: REVIEWED

    Conserved Domains (1) summary
    cl10013
    Location:26 → 169
    Glycosyltransferase_GTB-type; glycosyltransferase family 1 and related proteins with GTB topology

  2. NM_001313451.3 → NP_001300380.1  glucuronosyltransferase [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A0K3ATD5
    Conserved Domains (1) summary
    cl10013
    Location:9 → 144
    Glycosyltransferase_GTB_type; Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate ...

  3. NM_171786.8 → NP_741913.1  Putative UDP-glucuronosyltransferase ugt-50 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_741913.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O62371, Q22295, Q8MPX8
    Conserved Domains (2) summary
    PHA03392
    Location:9 → 475
    egt; ecdysteroid UDP-glucosyltransferase; Provisional
    pfam00201
    Location:26 → 520
    UDPGT; UDP-glucoronosyl and UDP-glucosyl transferase

  4. NM_001313450.3 → NP_001300379.1  UDP-glucuronosyltransferase [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A0K3AYM2
    Conserved Domains (1) summary
    PHA03392
    Location:130 → 376
    egt; ecdysteroid UDP-glucosyltransferase; Provisional
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q22295.2

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