U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

gyg-1 Glycogenin-1 [ Caenorhabditis elegans ]

Gene ID: 180644, updated on 23-Nov-2023

Summary

Go to the top of the page Help
Gene symbol
gyg-1
Gene description
Glycogenin-1
Primary source
WormBase:WBGene00006863
Locus tag
CELE_F56B6.4
See related
AllianceGenome:WB:WBGene00006863
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable glycosyltransferase activity. Predicted to be involved in glycogen biosynthetic process. Located in striated muscle dense body. Is expressed in several structures, including body wall musculature; hypodermis; intestine; pharynx; and vulval muscle. Human ortholog(s) of this gene implicated in glycogen storage disease and glycogen storage disease XV. Orthologous to several human genes including GYG1 (glycogenin 1). [provided by Alliance of Genome Resources, Apr 2022]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
chromosome: X
Exon count:
8
Sequence:
Chromosome: X; NC_003284.9 (3537635..3540943)

Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene G-protein coupled receptors family 1 profile domain-containing protein Neighboring gene ncRNA Neighboring gene CC domain-containing protein Neighboring gene C2 domain-containing protein;RGS domain-containing protein;Regulator of G-protein signaling rgs-7 Neighboring gene Vitellogenin-4 Neighboring gene ncRNA

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_003284.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Structural basis for the recruitment of glycogen synthase by glycogenin. Zeqiraj E, et al. Proc Natl Acad Sci U S A, 2014 Jul 15. PMID 24982189, Free PMC Article
  2. Characterization of regions of the Caenorhabditis elegans X chromosome containing vitellogenin genes. Heine U, et al. J Mol Biol, 1986 Apr 5. PMID 3735423
  3. High qualitative and quantitative conservation of alternative splicing in Caenorhabditis elegans and Caenorhabditis briggsae. Rukov JL, et al. Mol Biol Evol, 2007 Apr. PMID 17272679
  4. Determining the sub-cellular localization of proteins within Caenorhabditis elegans body wall muscle. Meissner B, et al. PLoS One, 2011. PMID 21611156, Free PMC Article
  5. The conserved histone chaperone LIN-53 is required for normal lifespan and maintenance of muscle integrity in Caenorhabditis elegans. Müthel S, et al. Aging Cell, 2019 Dec. PMID 31397537, Free PMC Article

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

Go to the top of the page

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables UDP-alpha-D-glucose:glucosyl-glycogenin alpha-D-glucosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables glycogenin glucosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables glycosyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables glycosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in glycogen biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm HDA PubMed 
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in striated muscle dense body HDA PubMed 

General protein information

Go to the top of the page Help
Preferred Names
Glycogenin-1
NP_508608.1
  • Confirmed by transcript evidence
NP_508609.1
  • Confirmed by transcript evidence
NP_741749.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003284.9 Reference assembly

    Range
    3537635..3540943
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_171944.9 → NP_741749.1  Glycogenin-1 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_741749.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    H2KYQ5
    Conserved Domains (2) summary
    cd02537
    Location:3 → 238
    GT8_Glycogenin; Glycogenin belongs the GT 8 family and initiates the biosynthesis of glycogen
    COG1442
    Location:6 → 220
    RfaJ; Lipopolysaccharide biosynthesis protein, LPS:glycosyltransferase [Cell wall/membrane/envelope biogenesis]

  2. NM_076207.8 → NP_508608.1  Glycogenin-1 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_508608.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    H2KYQ5, H2KYQ6, Q95Q50
    Conserved Domains (2) summary
    cd02537
    Location:3 → 238
    GT8_Glycogenin; Glycogenin belongs the GT 8 family and initiates the biosynthesis of glycogen
    COG1442
    Location:6 → 220
    RfaJ; Lipopolysaccharide biosynthesis protein, LPS:glycosyltransferase [Cell wall/membrane/envelope biogenesis]

  3. NM_076208.7 → NP_508609.1  Glycogenin-1 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_508609.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    H2KYQ5
    Conserved Domains (2) summary
    cd02537
    Location:3 → 238
    GT8_Glycogenin; Glycogenin belongs the GT 8 family and initiates the biosynthesis of glycogen
    COG1442
    Location:6 → 220
    RfaJ; Lipopolysaccharide biosynthesis protein, LPS:glycosyltransferase [Cell wall/membrane/envelope biogenesis]
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
H2KYQ5.1

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools
Miscellaneous