decr-1.1 putative oxidoreductase F53C11.3 [Caenorhabditis elegans] - Gene

Summary

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Gene symbol: decr-1.1
Gene description: putative oxidoreductase F53C11.3
Primary source: WormBase:WBGene00009973
Locus tag: CELE_F53C11.3
See related: AllianceGenome:WB:WBGene00009973
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable 2,4-dienoyl-CoA reductase (NADPH) activity. Involved in defense response to Gram-negative bacterium and innate immune response. Predicted to be active in mitochondrion. Is expressed in intestine. Orthologous to human DECR1 (2,4-dienoyl-CoA reductase 1). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:: chromosome: V

Exon count:: 4

Sequence:: Chromosome: V; NC_003283.11 (13782399..13784109)

Chromosome V - NC_003283.11 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

F53C11.3 (e-PCR)
- UniSTS:306355

F53C11.2 (e-PCR)
- UniSTS:307692

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables 2,4-dienoyl-CoA reductase (NADPH) activity	IBA Inferred from Biological aspect of Ancestor more info
enables oxidoreductase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in defense response to Gram-negative bacterium	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in fatty acid beta-oxidation	IBA Inferred from Biological aspect of Ancestor more info
involved_in innate immune response	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
is_active_in mitochondrion	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: putative oxidoreductase F53C11.3

NP_506413.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003283.11 Reference assembly

Range

13782399..13784109

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_074012.7 → NP_506413.1 putative oxidoreductase F53C11.3 [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_506413.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q93761

Conserved Domains (2) summary

PRK07677
Location:40 → 273

PRK07677; short chain dehydrogenase; Provisional

cd05369
Location:40 → 275

TER_DECR_SDR_a; Trans-2-enoyl-CoA reductase (TER) and 2,4-dienoyl-CoA reductase (DECR), atypical (a) SDR