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rbm-17 Splicing factor 45 [ Caenorhabditis elegans ]

Gene ID: 178091, updated on 23-Nov-2023

Summary

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Gene symbol
rbm-17
Gene description
Splicing factor 45
Primary source
WormBase:WBGene00010233
Locus tag
CELE_F58B3.7
See related
AllianceGenome:WB:WBGene00010233
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable RNA binding activity. Predicted to be involved in alternative mRNA splicing, via spliceosome. Predicted to be located in nucleoplasm. Predicted to be part of spliceosomal complex. Orthologous to human RBM17 (RNA binding motif protein 17). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
chromosome: IV
Exon count:
4
Sequence:
Chromosome: IV; NC_003282.8 (11638316..11640097)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Methionine--tRNA ligase, cytoplasmic;tRNA-binding domain-containing protein Neighboring gene ncRNA Neighboring gene Interferon-related developmental regulator N-terminal domain-containing protein Neighboring gene Transthyretin-like family protein Neighboring gene Tyrosine-protein phosphatase domain-containing protein Neighboring gene RING-type domain-containing protein Neighboring gene Cardiac phospholamban

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A novel DNA repair enzyme containing RNA recognition, G-patch and specific splicing factor 45-like motifs in the protozoan parasite Toxoplasma gondii. Dendouga N, et al. Eur J Biochem, 2002 Jul. PMID 12135477
  2. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
  3. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
  4. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
  5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in RNA splicing IEA
Inferred from Electronic Annotation
more info
  
involved_in alternative mRNA splicing, via spliceosome IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in mRNA cis splicing, via spliceosome IEA
Inferred from Electronic Annotation
more info
  
involved_in mRNA processing IEA
Inferred from Electronic Annotation
more info
  
involved_in mRNA splicing, via spliceosome IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in nucleoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
part_of spliceosomal complex IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Splicing factor 45
NP_502198.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    11638316..11640097
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_069797.7 → NP_502198.1  Splicing factor 45 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_502198.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q20966
    Conserved Domains (2) summary
    cd12374
    Location:273 → 362
    RRM_UHM_SPF45_PUF60; RNA recognition motif in UHM domain of 45 kDa-splicing factor (SPF45) and similar proteins
    pfam01585
    Location:211 → 254
    G-patch; G-patch domain
Nucleotide Protein
Heading Accession and Version

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