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Y55F3BR.1 ATP-dependent RNA helicase [ Caenorhabditis elegans ]

Gene ID: 176913, updated on 11-Apr-2024

Summary

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Gene symbol
Y55F3BR.1
Gene description
ATP-dependent RNA helicase
Primary source
WormBase:WBGene00021938
Locus tag
CELE_Y55F3BR.1
See related
AllianceGenome:WB:WBGene00021938
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable several functions, including ATP binding activity; RNA helicase activity; and exonuclease activity. Predicted to be involved in nucleic acid phosphodiester bond hydrolysis. Orthologous to human DDX1 (DEAD-box helicase 1). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
chromosome: IV
Exon count:
9
Sequence:
Chromosome: IV; NC_003282.8 (874791..881910)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene BPTI/Kunitz inhibitor domain-containing protein;EB domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene MAP kinase-activated protein kinase mak-2 Neighboring gene F-box C protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. TLR-independent control of innate immunity in Caenorhabditis elegans by the TIR domain adaptor protein TIR-1, an ortholog of human SARM. Couillault C, et al. Nat Immunol, 2004 May. PMID 15048112
  2. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
  3. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
  4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
enables RNA helicase activity IEA
Inferred from Electronic Annotation
more info
  
enables exonuclease activity IEA
Inferred from Electronic Annotation
more info
  
enables helicase activity IEA
Inferred from Electronic Annotation
more info
  
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables nuclease activity IEA
Inferred from Electronic Annotation
more info
  
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
  
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
ATP-dependent RNA helicase
NP_500004.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    874791..881910
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_067603.7 → NP_500004.2  ATP-dependent RNA helicase [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_500004.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9N341
    Conserved Domains (4) summary
    COG0513
    Location:278 → 614
    SrmB; Superfamily II DNA and RNA helicase [Replication, recombination and repair]
    pfam00271
    Location:492 → 599
    Helicase_C; Helicase conserved C-terminal domain
    cd12873
    Location:89 → 244
    SPRY_DDX1; SPRY domain associated with DEAD box gene DDX1
    cl21455
    Location:282 → 420
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
Nucleotide Protein
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