Y55F3BR.1 ATP-dependent RNA helicase DDX1 [Caenorhabditis elegans] - Gene

Summary

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Gene symbol: Y55F3BR.1
Gene description: ATP-dependent RNA helicase DDX1
Primary source: WormBase:WBGene00021938
Locus tag: CELE_Y55F3BR.1
See related: AllianceGenome:WB:WBGene00021938
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable several functions, including ATP binding activity; RNA helicase activity; and exonuclease activity. Predicted to be involved in nucleic acid phosphodiester bond hydrolysis. Orthologous to human DDX1 (DEAD-box helicase 1). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See Y55F3BR.1 in Genome Data Viewer

Location:: chromosome: IV

Exon count:: 9

Sequence:: Chromosome: IV; NC_003282.8 (874791..881910)

Chromosome IV - NC_003282.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

C44C8.5 (e-PCR)
- UniSTS:319131

STS4-103 (e-PCR)
- UniSTS:242090

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables DNA binding	IEA Inferred from Electronic Annotation more info
enables RNA binding	IEA Inferred from Electronic Annotation more info
enables RNA helicase activity	IEA Inferred from Electronic Annotation more info
enables exonuclease activity	IEA Inferred from Electronic Annotation more info
enables helicase activity	IEA Inferred from Electronic Annotation more info
enables hydrolase activity	IEA Inferred from Electronic Annotation more info
enables nuclease activity	IEA Inferred from Electronic Annotation more info
enables nucleic acid binding	IEA Inferred from Electronic Annotation more info
enables nucleotide binding	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: ATP-dependent RNA helicase DDX1

NP_500004.2

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003282.8 Reference assembly

Range

874791..881910

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_067603.7 → NP_500004.2 ATP-dependent RNA helicase DDX1 [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_500004.2

Status: REVIEWED

UniProtKB/TrEMBL

Q9N341

Conserved Domains (4) summary

COG0513
Location:278 → 614

SrmB; Superfamily II DNA and RNA helicase [Replication, recombination and repair]

pfam00271
Location:492 → 599

Helicase_C; Helicase conserved C-terminal domain

cd12873
Location:89 → 244

SPRY_DDX1; SPRY domain associated with DEAD box gene DDX1

cl21455
Location:282 → 420

P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases