ugtp-1 UDP-galactose translocator 1 [Caenorhabditis elegans] - Gene

Summary

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Gene symbol: ugtp-1
Gene description: UDP-galactose translocator 1
Primary source: WormBase:WBGene00022721
Locus tag: CELE_ZK370.7
See related: AllianceGenome:WB:WBGene00022721
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable UDP-galactose transmembrane transporter activity. Predicted to be involved in UDP-galactose transmembrane transport and carbohydrate transport. Located in Golgi medial cisterna and cortical granule. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation type IIf. Orthologous to human SLC35A1 (solute carrier family 35 member A1). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See ugtp-1 in Genome Data Viewer

Location:: chromosome: III

Exon count:: 6

Sequence:: Chromosome: III; NC_003281.10 (8746216..8748701, complement)

Chromosome III - NC_003281.10 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

ZK370.7 (e-PCR)
- UniSTS:318741

ZK370.9 (e-PCR)
- UniSTS:316295

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables CMP-N-acetylneuraminate transmembrane transporter activity	IBA Inferred from Biological aspect of Ancestor more info
enables pyrimidine nucleotide-sugar transmembrane transporter activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in CMP-N-acetylneuraminate transmembrane transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in carbohydrate transport	IEA Inferred from Electronic Annotation more info
involved_in pyrimidine nucleotide-sugar transmembrane transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in Golgi medial cisterna	IDA Inferred from Direct Assay more info	PubMed
is_active_in Golgi membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in Golgi membrane	IEA Inferred from Electronic Annotation more info
located_in cortical granule	IDA Inferred from Direct Assay more info	PubMed
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: UDP-galactose translocator 1

NP_498930.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

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Reference assembly

Genomic

NC_003281.10 Reference assembly

Range

8746216..8748701 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_066529.8 → NP_498930.1 UDP-galactose translocator 1 [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_498930.1

Status: REVIEWED

UniProtKB/Swiss-Prot

P34632, Q02334

Conserved Domains (2) summary

TIGR00803
Location:122 → 350

nst; UDP-galactose transporter

pfam04142
Location:37 → 351

Nuc_sug_transp; Nucleotide-sugar transporter