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eef-1B.1 putative elongation factor 1-beta/1-delta 1 [ Caenorhabditis elegans ]

Gene ID: 176120, updated on 23-Nov-2023

Summary

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Gene symbol
eef-1B.1
Gene description
putative elongation factor 1-beta/1-delta 1
Primary source
WormBase:WBGene00018846
Locus tag
CELE_F54H12.6
See related
AllianceGenome:WB:WBGene00018846
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be involved in translational elongation. Predicted to be active in cytosol. Orthologous to several human genes including EEF1B2 (eukaryotic translation elongation factor 1 beta 2). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
chromosome: III
Exon count:
3
Sequence:
Chromosome: III; NC_003281.10 (7972382..7973386, complement)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Envelope glycoprotein B Neighboring gene ADP-ribosylation factor-like protein 6-interacting protein 4 Neighboring gene Uncharacterized protein Neighboring gene ncRNA Neighboring gene putative aconitate hydratase, mitochondrial Neighboring gene Uncharacterized protein Neighboring gene tRNA-Phe Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Global Proteomic Response of Caenorhabditis elegans Against PemK(Sa) Toxin. Mir DA, et al. Front Cell Infect Microbiol, 2019. PMID 31214513, Free PMC Article
  2. A UPR-independent infection-specific role for a BiP/GRP78 protein in the control of antimicrobial peptide expression in C. elegans epidermis. Couillault C, et al. Virulence, 2012 May 1. PMID 22546897, Free PMC Article
  3. Mechanism and regulation of translation in C. elegans. Rhoads RE, et al. WormBook, 2006 Jan 28. PMID 18050488, Free PMC Article
  4. LIN-41 and OMA Ribonucleoprotein Complexes Mediate a Translational Repression-to-Activation Switch Controlling Oocyte Meiotic Maturation and the Oocyte-to-Embryo Transition in Caenorhabditis elegans. Tsukamoto T, et al. Genetics, 2017 Aug. PMID 28576864, Free PMC Article
  5. The RNA-binding protein repertoire of Arabidopsis thaliana. Marondedze C, et al. Sci Rep, 2016 Jul 11. PMID 27405932, Free PMC Article

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables guanyl-nucleotide exchange factor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables translation elongation factor activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in translation IEA
Inferred from Electronic Annotation
more info
  
involved_in translational elongation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in translational elongation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
putative elongation factor 1-beta/1-delta 1
NP_498737.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    7972382..7973386 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_066336.8 → NP_498737.1  putative elongation factor 1-beta/1-delta 1 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_498737.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P34460
    Conserved Domains (3) summary
    pfam00736
    Location:129 → 213
    EF1_GNE; EF-1 guanine nucleotide exchange domain
    pfam10587
    Location:90 → 110
    EF-1_beta_acid; Eukaryotic elongation factor 1 beta central acidic region
    cl02776
    Location:1 → 62
    GST_C_family; C-terminal, alpha helical domain of the Glutathione S-transferase family
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P34460.1

Gene LinkOut

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