ubq-1 Ubiquitin-related [Caenorhabditis elegans] - Gene

Summary

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Gene symbol: ubq-1
Gene description: Ubiquitin-related
Primary source: WormBase:WBGene00006727
Locus tag: CELE_F25B5.4
See related: AllianceGenome:WB:WBGene00006727
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable protein tag and ubiquitin protein ligase binding activity. Involved in ubiquitin-dependent protein catabolic process. Predicted to be active in cytoplasm and nucleus. Is expressed in body wall musculature; hypodermis; and neurons. Orthologous to several human genes including UBC (ubiquitin C). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:: chromosome: III

Exon count:: 5

Sequence:: Chromosome: III; NC_003281.10 (5940986..5943827)

Chromosome III - NC_003281.10 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

F25B5.4 (e-PCR)
- UniSTS:306200

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables protein tag activity	IBA Inferred from Biological aspect of Ancestor more info
enables ubiquitin protein ligase binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in modification-dependent protein catabolic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in programmed cell death involved in cell development	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in protein ubiquitination	IBA Inferred from Biological aspect of Ancestor more info
involved_in ubiquitin-dependent protein catabolic process	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: Ubiquitin-related

NP_741157.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003281.10 Reference assembly

Range

5940986..5943827

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_171139.8 → NP_741157.1 Ubiquitin-related [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_741157.1

Status: REVIEWED

UniProtKB/Swiss-Prot

P0CG71

Conserved Domains (2) summary

cd01803
Location:77 → 152

Ubiquitin; Ubiquitin

smart00213
Location:1 → 72

UBQ; Ubiquitin homologues