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rps-12 Small ribosomal subunit protein eS12 [ Caenorhabditis elegans ]

Gene ID: 175786, updated on 5-May-2024

Summary

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Gene symbol
rps-12
Gene description
Small ribosomal subunit protein eS12
Primary source
WormBase:WBGene00004481
Locus tag
CELE_F54E7.2
See related
AllianceGenome:WB:WBGene00004481
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Predicted to be located in ribosome. Predicted to be part of cytosolic small ribosomal subunit. Orthologous to human RPS12 (ribosomal protein S12). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
chromosome: III
Exon count:
3
Sequence:
Chromosome: III; NC_003281.10 (5679298..5680187)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene PDZ domain-containing protein;Partitioning defective protein 3 Neighboring gene N-acetyltransferase domain-containing protein Neighboring gene Spindle and Kinetochore-Associated protein homolog Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Adenosine 3'-phospho 5'-phosphosulfate transporter 2 Neighboring gene Calcipressin-like protein Neighboring gene SH3 domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Isolation of eight novel Caenorhabditis elegans small RNAs. Wachi M, et al. Gene, 2004 Jun 23. PMID 15194189
  2. The ribosomal protein RACK1 is required for microRNA function in both C. elegans and humans. Jannot G, et al. EMBO Rep, 2011 Jun. PMID 21525958, Free PMC Article
  3. Establishing a blueprint for CED-3-dependent killing through identification of multiple substrates for this protease. Taylor RC, et al. J Biol Chem, 2007 May 18. PMID 17371877
  4. Delayed development and lifespan extension as features of metabolic lifestyle alteration in C. elegans under dietary restriction. Szewczyk NJ, et al. J Exp Biol, 2006 Oct. PMID 17023606
  5. The nascent polypeptide-associated complex is a key regulator of proteostasis. Kirstein-Miles J, et al. EMBO J, 2013 May 15. PMID 23604074, Free PMC Article

See all (17) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
  
enables structural constituent of ribosome IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in maintenance of translational fidelity IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in ribosomal small subunit biogenesis IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in ribosomal small subunit biogenesis ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in translation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cellular anatomical entity IEA
Inferred from Electronic Annotation
more info
  
part_of cytosolic small ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleolus IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
  
located_in ribosome IEA
Inferred from Electronic Annotation
more info
  
part_of small-subunit processome ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
Small ribosomal subunit protein eS12
NP_498221.1
  • Partially confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    5679298..5680187
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_065820.8 → NP_498221.1  Small ribosomal subunit protein eS12 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_498221.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P49196
    Conserved Domains (1) summary
    pfam01248
    Location:25 → 119
    Ribosomal_L7Ae; Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P49196.2

Gene LinkOut

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