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mog-4 putative pre-mRNA-splicing factor ATP-dependent RNA helicase mog-4 [ Caenorhabditis elegans ]

Gene ID: 175117, updated on 5-May-2024

Summary

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Gene symbol
mog-4
Gene description
putative pre-mRNA-splicing factor ATP-dependent RNA helicase mog-4
Primary source
WormBase:WBGene00003392
Locus tag
CELE_C04H5.6
See related
AllianceGenome:WB:WBGene00003392
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable RNA binding activity. Involved in several processes, including embryonic body morphogenesis; feminization of hermaphroditic germ-line; and germ cell development. Predicted to be located in nucleus. Orthologous to human DHX16 (DEAH-box helicase 16). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
chromosome: II
Exon count:
10
Sequence:
Chromosome: II; NC_003280.10 (14552504..14561599, complement)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Neuropeptide-Like Protein;Toxin Neighboring gene pseudo Neighboring gene Receptor-type guanylate cyclase gcy-29 Neighboring gene Neuropeptide-Like Protein Neighboring gene ncRNA Neighboring gene pseudo Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The Caenorhabditis elegans DDX-23, a homolog of yeast splicing factor PRP28, is required for the sperm-oocyte switch and differentiation of various cell types. Konishi T, et al. Dev Dyn, 2008 Sep. PMID 18729217
  2. The hermaphrodite sperm/oocyte switch requires the Caenorhabditis elegans homologs of PRP2 and PRP22. Puoti A, et al. Proc Natl Acad Sci U S A, 2000 Mar 28. PMID 10737793, Free PMC Article
  3. The MEP-1 zinc-finger protein acts with MOG DEAH box proteins to control gene expression via the fem-3 3' untranslated region in Caenorhabditis elegans. Belfiore M, et al. RNA, 2002 Jun. PMID 12088146, Free PMC Article
  4. Gametogenesis: keeping the male element under control. Kuwabara PE. Curr Biol, 1998 Apr 9. PMID 9550693
  5. Roles of the C. elegans cyclophilin-like protein MOG-6 in MEP-1 binding and germline fates. Belfiore M, et al. Development, 2004 Jun. PMID 15151984

See all (28) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
  
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA helicase activity IEA
Inferred from Electronic Annotation
more info
  
enables helicase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables helicase activity IEA
Inferred from Electronic Annotation
more info
  
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
  
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in RNA splicing IEA
Inferred from Electronic Annotation
more info
  
involved_in developmental growth IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in embryonic body morphogenesis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in feminization of hermaphroditic germ-line IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in germ cell development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in mRNA processing IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in intracellular anatomical structure IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
putative pre-mRNA-splicing factor ATP-dependent RNA helicase mog-4
NP_001293532.1
  • Confirmed by transcript evidence
NP_497027.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    14552504..14561599 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_064626.6 → NP_497027.1  putative pre-mRNA-splicing factor ATP-dependent RNA helicase mog-4 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_497027.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O45239, O45244
    Conserved Domains (6) summary
    smart00487
    Location:370 → 546
    DEXDc; DEAD-like helicases superfamily
    smart00847
    Location:764 → 848
    HA2; Helicase associated domain (HA2) Add an annotation
    cd00046
    Location:381 → 520
    DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
    pfam00271
    Location:577 → 696
    Helicase_C; Helicase conserved C-terminal domain
    pfam07717
    Location:872 → 981
    OB_NTP_bind; Oligonucleotide/oligosaccharide-binding (OB)-fold
    pfam08070
    Location:103 → 162
    DTHCT; DTHCT (NUC029) region

  2. NM_001306603.4 → NP_001293532.1  putative pre-mRNA-splicing factor ATP-dependent RNA helicase mog-4 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001293532.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    U4PDV5
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O45244.2

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