rpn-9 26S proteasome non-ATPase regulatory subunit 13 [Caenorhabditis elegans] - Gene

Summary

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Gene symbol: rpn-9
Gene description: 26S proteasome non-ATPase regulatory subunit 13
Primary source: WormBase:WBGene00004465
Locus tag: CELE_T06D8.8
See related: AllianceGenome:WB:WBGene00004465
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable structural molecule activity. Predicted to be involved in ubiquitin-dependent protein catabolic process. Predicted to be part of proteasome regulatory particle, lid subcomplex. Predicted to be active in cytosol and nucleus. Is expressed in intestine and rectal gland cell. Orthologous to human PSMD13 (proteasome 26S subunit, non-ATPase 13). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:: chromosome: II

Exon count:: 4

Sequence:: Chromosome: II; NC_003280.10 (11237447..11238919, complement)

Chromosome II - NC_003280.10 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

BAP1 Malignant Pleural Mesothelioma Mutations in Caenorhabditis elegans Reveal Synthetic Lethality between ubh-4/BAP1 and the Proteasome Subunit rpn-9/PSMD13.
Title: BAP1 Malignant Pleural Mesothelioma Mutations in Caenorhabditis elegans Reveal Synthetic Lethality between ubh-4/BAP1 and the Proteasome Subunit rpn-9/PSMD13.

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Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

T06D8.8 (e-PCR)
- UniSTS:307947

T06D8.9 (e-PCR)
- UniSTS:307948

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables structural molecule activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in ubiquitin-dependent protein catabolic process	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in cytosol	IBA Inferred from Biological aspect of Ancestor more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
part_of proteasome complex	IEA Inferred from Electronic Annotation more info
part_of proteasome regulatory particle	ISS Inferred from Sequence or Structural Similarity more info	PubMed
part_of proteasome regulatory particle, lid subcomplex	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: 26S proteasome non-ATPase regulatory subunit 13

NP_496405.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003280.10 Reference assembly

Range

11237447..11238919 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_064004.8 → NP_496405.1 26S proteasome non-ATPase regulatory subunit 13 [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_496405.1

Status: REVIEWED

UniProtKB/TrEMBL

Q22253

Conserved Domains (1) summary

smart00753
Location:272 → 365

PAM; PCI/PINT associated module