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rsp-7 putative splicing factor, arginine/serine-rich 7 [ Caenorhabditis elegans ]

Gene ID: 174646, updated on 23-Nov-2023

Summary

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Gene symbol
rsp-7
Gene description
putative splicing factor, arginine/serine-rich 7
Primary source
WormBase:WBGene00004704
Locus tag
CELE_D2089.1
See related
AllianceGenome:WB:WBGene00004704
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable RNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be located in nucleus. Predicted to be active in nucleoplasm. Orthologous to human SRSF11 (serine and arginine rich splicing factor 11) and SREK1 (splicing regulatory glutamic acid and lysine rich protein 1). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
chromosome: II
Exon count:
6
Sequence:
Chromosome: II; NC_003280.10 (10659206..10662317)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene NHP2-like protein 1 homolog Neighboring gene ncRNA Neighboring gene RING-CH-type domain-containing protein Neighboring gene Cysteine-rich DPF motif domain-containing protein 1 Neighboring gene Secreted protein Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional characterization of SR and SR-related genes in Caenorhabditis elegans. Longman D, et al. EMBO J, 2000 Apr 3. PMID 10747030, Free PMC Article
  2. Functional genomic analysis of RNA interference in C. elegans. Kim JK, et al. Science, 2005 May 20. PMID 15790806
  3. A genomewide RNAi screen for genes that affect the stability, distribution and function of P granules in Caenorhabditis elegans. Updike DL, et al. Genetics, 2009 Dec. PMID 19805813, Free PMC Article
  4. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
  5. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in RNA splicing IEA
Inferred from Electronic Annotation
more info
  
involved_in mRNA processing IEA
Inferred from Electronic Annotation
more info
  
involved_in mRNA splicing, via spliceosome ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Component Evidence Code Pubs
is_active_in nucleoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
putative splicing factor, arginine/serine-rich 7
NP_001369854.1
  • Confirmed by transcript evidence
NP_001379303.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    10659206..10662317
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001393181.1 → NP_001379303.1  putative splicing factor, arginine/serine-rich 7 [Caenorhabditis elegans]

    Status: REVIEWED

    Conserved Domains (1) summary
    cd12259
    Location:11 → 87
    RRM_SRSF11_SREK1; RNA recognition motif (RRM) found in serine/arginine-rich splicing factor 11 (SRSF11), splicing regulatory glutamine/lysine-rich protein 1 (SREK1) and similar proteins

  2. NM_001383939.2 → NP_001369854.1  putative splicing factor, arginine/serine-rich 7 [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O01159, P90797, Q8STE7
    Conserved Domains (2) summary
    cd12259
    Location:11 → 87
    RRM_SRSF11_SREK1; RNA recognition motif (RRM) found in serine/arginine-rich splicing factor 11 (SRSF11), splicing regulatory glutamine/lysine-rich protein 1 (SREK1) and similar proteins
    cl17169
    Location:159 → 245
    RRM_SF; RNA recognition motif (RRM) superfamily
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O01159.3

Gene LinkOut

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