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rpl-26 Large ribosomal subunit protein uL24 [ Caenorhabditis elegans ]

Gene ID: 174379, updated on 5-May-2024

Summary

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Gene symbol
rpl-26
Gene description
Large ribosomal subunit protein uL24
Primary source
WormBase:WBGene00004440
Locus tag
CELE_F28C6.7
See related
AllianceGenome:WB:WBGene00004440
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable RNA binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in cytoplasmic translation and ribosomal large subunit biogenesis. Predicted to be located in ribosome. Predicted to be part of cytosolic large ribosomal subunit. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia 11. Orthologous to human RPL26 (ribosomal protein L26) and RPL26L1 (ribosomal protein L26 like 1). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
chromosome: II
Exon count:
3
Sequence:
Chromosome: II; NC_003280.10 (8602787..8603581)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Transcription factor AP-2 C-terminal domain-containing protein Neighboring gene GPI ethanolamine phosphate transferase 2 Neighboring gene Amelotin Neighboring gene Cleavage stimulation factor 50 kDa subunit Neighboring gene ncRNA Neighboring gene Suppressor of forked domain-containing protein Neighboring gene TYR_PHOSPHATASE_2 domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The insulin/IGF signaling cascade modulates SUMOylation to regulate aging and proteostasis in Caenorhabditis elegans. Moll L, et al. Elife, 2018 Nov 7. PMID 30403374, Free PMC Article
  2. The ribonucleotidyl transferase USIP-1 acts with SART3 to promote U6 snRNA recycling. Rüegger S, et al. Nucleic Acids Res, 2015 Mar 31. PMID 25753661, Free PMC Article
  3. The Balance between Mono- and NEDD8-Chains Controlled by NEDP1 upon DNA Damage Is a Regulatory Module of the HSP70 ATPase Activity. Bailly AP, et al. Cell Rep, 2019 Oct 1. PMID 31577950, Free PMC Article
  4. The nascent polypeptide-associated complex is a key regulator of proteostasis. Kirstein-Miles J, et al. EMBO J, 2013 May 15. PMID 23604074, Free PMC Article
  5. The Caenorhabditis elegans RDE-10/RDE-11 complex regulates RNAi by promoting secondary siRNA amplification. Zhang C, et al. Curr Biol, 2012 May 22. PMID 22542102, Free PMC Article

See all (15) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
  
enables structural constituent of ribosome IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in cytoplasmic translation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in ribosomal large subunit biogenesis IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in translation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of cytosolic large ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of large ribosomal subunit IEA
Inferred from Electronic Annotation
more info
  
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
  
located_in ribosome IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Large ribosomal subunit protein uL24
NP_001366756.1
  • Confirmed by transcript evidence
NP_495823.1
  • Confirmed by transcript evidence
NP_871965.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    8602787..8603581
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_063422.8 → NP_495823.1  Large ribosomal subunit protein uL24 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_495823.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q19869, Q8I121, Q9U3H7
    Conserved Domains (1) summary
    pfam16906
    Location:8 → 121
    Ribosomal_L26; Ribosomal proteins L26 eukaryotic, L24P archaeal

  2. NM_001381531.3 → NP_001366756.1  Large ribosomal subunit protein uL24 [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A146I8J1
    Conserved Domains (1) summary
    pfam16906
    Location:8 → 103
    Ribosomal_L26; Ribosomal proteins L26 eukaryotic, L24P archaeal

  3. NM_182165.8 → NP_871965.1  Large ribosomal subunit protein uL24 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_871965.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q19869
    Conserved Domains (1) summary
    pfam16906
    Location:8 → 103
    Ribosomal_L26; Ribosomal proteins L26 eukaryotic, L24P archaeal
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q19869.1

Gene LinkOut

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