pgm-1 phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent) [Caenorhabditis elegans] - Gene

Summary

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Gene symbol: pgm-1
Gene description: phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent)
Primary source: WormBase:WBGene00019890
Locus tag: CELE_R05F9.6
See related: AllianceGenome:WB:WBGene00019890
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable phosphoglucomutase activity. Predicted to be involved in carbohydrate metabolic process. Predicted to be active in cytosol. Is expressed in several structures, including body wall musculature; hypodermis; intestine; pharynx; and vulval muscle. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation It; endometrial cancer; and teratoma. Orthologous to human PGM1 (phosphoglucomutase 1) and PGM5 (phosphoglucomutase 5). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See pgm-1 in Genome Data Viewer

Location:: chromosome: II

Exon count:: 4

Sequence:: Chromosome: II; NC_003280.10 (4889437..4891405)

Chromosome II - NC_003280.10 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

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Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

R05F9.6 (e-PCR)
- UniSTS:312055

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables intramolecular phosphotransferase activity	IEA Inferred from Electronic Annotation more info
enables isomerase activity	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables phosphoglucomutase activity	IBA Inferred from Biological aspect of Ancestor more info
enables phosphoglucomutase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in carbohydrate metabolic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in carbohydrate metabolic process	IEA Inferred from Electronic Annotation more info
involved_in organic substance metabolic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in cytosol	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent)

NP_494886.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

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Reference assembly

Genomic

NC_003280.10 Reference assembly

Range

4889437..4891405

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_062485.7 → NP_494886.1 phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent) [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_494886.1

Status: REVIEWED

UniProtKB/TrEMBL

Q21742

Conserved Domains (2) summary

cd03085
Location:6 → 568

PGM1; Phosphoglucomutase 1 (PGM1) catalyzes the bidirectional interconversion of glucose-1-phosphate (G-1-P) and glucose-6-phosphate (G-6-P) via a glucose 1,6-diphosphate intermediate, an important metabolic step in prokaryotes and eukaryotes. In one direction, ...

PLN02307
Location:1 → 568

PLN02307; phosphoglucomutase