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plpp-1.1 Phosphatidic acid phosphatase type 2/haloperoxidase domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 173734, updated on 23-Nov-2023

Summary

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Gene symbol
plpp-1.1
Gene description
Phosphatidic acid phosphatase type 2/haloperoxidase domain-containing protein
Primary source
WormBase:WBGene00018756
Locus tag
CELE_F53C3.13
See related
AllianceGenome:WB:WBGene00018756
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable lipid phosphatase activity and phosphatidate phosphatase activity. Predicted to be involved in phospholipid dephosphorylation; phospholipid metabolic process; and signal transduction. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be integral component of plasma membrane. Orthologous to several human genes including PLPP1 (phospholipid phosphatase 1) and PLPP3 (phospholipid phosphatase 3). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
chromosome: II
Exon count:
8
Sequence:
Chromosome: II; NC_003280.10 (3919720..3927993, complement)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene F-box associated domain-containing protein Neighboring gene Beta,beta-carotene 9',10'-oxygenase Neighboring gene Protein kinase domain-containing protein Neighboring gene SPK domain-containing protein Neighboring gene C2H2-type domain-containing protein;DUF659 domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Oocyte signals derived from polyunsaturated fatty acids control sperm recruitment in vivo. Kubagawa HM, et al. Nat Cell Biol, 2006 Oct. PMID 16998478
  2. RNA targets and specificity of Staufen, a double-stranded RNA-binding protein in Caenorhabditis elegans. LeGendre JB, et al. J Biol Chem, 2013 Jan 25. PMID 23195953, Free PMC Article
  3. Comparative genomics and functional study of lipid metabolic genes in Caenorhabditis elegans. Zhang Y, et al. BMC Genomics, 2013 Mar 12. PMID 23496871, Free PMC Article
  4. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
  5. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables phosphatidate phosphatase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in phospholipid dephosphorylation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in phospholipid metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in phospholipid metabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
Phosphatidic acid phosphatase type 2/haloperoxidase domain-containing protein
NP_001342020.1
  • Confirmed by transcript evidence
NP_001342021.1
  • Confirmed by transcript evidence
NP_001380219.1
  • Confirmed by transcript evidence
NP_494696.1
  • Confirmed by transcript evidence
NP_872025.1
  • Confirmed by transcript evidence
NP_872026.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    3919720..3927993 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001355092.3 → NP_001342020.1  Phosphatidic acid phosphatase type 2/haloperoxidase domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A238ULT2
    Conserved Domains (1) summary
    cd03384
    Location:108 → 258
    PAP2_wunen; PAP2, wunen subfamily. Most likely a family of membrane associated phosphatidic acid phosphatases. Wunen is a drosophila protein expressed in the central nervous system, which provides repellent activity towards primordial germ cells (PGCs), controls the ...

  2. NM_001355093.3 → NP_001342021.1  Phosphatidic acid phosphatase type 2/haloperoxidase domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A238UKK1
    Conserved Domains (1) summary
    cd03384
    Location:110 → 260
    PAP2_wunen; PAP2, wunen subfamily. Most likely a family of membrane associated phosphatidic acid phosphatases. Wunen is a drosophila protein expressed in the central nervous system, which provides repellent activity towards primordial germ cells (PGCs), controls the ...

  3. NM_182225.6 → NP_872025.1  Phosphatidic acid phosphatase type 2/haloperoxidase domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_872025.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    H2KZD1
    Conserved Domains (1) summary
    cd03384
    Location:108 → 258
    PAP2_wunen; PAP2, wunen subfamily. Most likely a family of membrane associated phosphatidic acid phosphatases. Wunen is a drosophila protein expressed in the central nervous system, which provides repellent activity towards primordial germ cells (PGCs), controls the ...

  4. NM_182226.5 → NP_872026.1  Phosphatidic acid phosphatase type 2/haloperoxidase domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_872026.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    H2KZD2
    Conserved Domains (1) summary
    cd03384
    Location:108 → 258
    PAP2_wunen; PAP2, wunen subfamily. Most likely a family of membrane associated phosphatidic acid phosphatases. Wunen is a drosophila protein expressed in the central nervous system, which provides repellent activity towards primordial germ cells (PGCs), controls the ...

  5. NM_062295.6 → NP_494696.1  Phosphatidic acid phosphatase type 2/haloperoxidase domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_494696.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9TXU1
    Conserved Domains (1) summary
    cd03384
    Location:108 → 258
    PAP2_wunen; PAP2, wunen subfamily. Most likely a family of membrane associated phosphatidic acid phosphatases. Wunen is a drosophila protein expressed in the central nervous system, which provides repellent activity towards primordial germ cells (PGCs), controls the ...

  6. NM_001393048.1 → NP_001380219.1  Phosphatidic acid phosphatase type 2/haloperoxidase domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A238UKJ7
    Conserved Domains (1) summary
    cd03384
    Location:108 → 258
    PAP2_wunen; PAP2, wunen subfamily. Most likely a family of membrane associated phosphatidic acid phosphatases. Wunen is a drosophila protein expressed in the central nervous system, which provides repellent activity towards primordial germ cells (PGCs), controls the ...
Nucleotide Protein
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