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eif-3.E Eukaryotic translation initiation factor 3 subunit E [ Caenorhabditis elegans ]

Gene ID: 172959, updated on 5-May-2024

Summary

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Gene symbol
eif-3.E
Gene description
Eukaryotic translation initiation factor 3 subunit E
Primary source
WormBase:WBGene00001228
Locus tag
CELE_B0511.10
See related
AllianceGenome:WB:WBGene00001228
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable translation initiation factor activity. Predicted to be involved in translational initiation. Predicted to be located in cytoplasm. Predicted to be part of eukaryotic translation initiation factor 3 complex. Predicted to be active in nucleus. Is expressed in several structures, including anal depressor muscle; excretory cell; head; hypodermis; and reproductive system. Orthologous to human EIF3E (eukaryotic translation initiation factor 3 subunit E). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
chromosome: I
Exon count:
4
Sequence:
Chromosome: I; NC_003279.8 (10640465..10642281, complement)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Mitochondrial Ribosomal Protein, Small Neighboring gene Anaphase-promoting complex subunit CDC26 Neighboring gene DUF4283 domain-containing protein Neighboring gene Protein kinase domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003279.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Non-proteolytic activity of 19S proteasome subunit RPT-6 regulates GATA transcription during response to infection. Olaitan AO, et al. PLoS Genet, 2018 Sep. PMID 30265660, Free PMC Article
  2. Mechanism and regulation of translation in C. elegans. Rhoads RE, et al. WormBook, 2006 Jan 28. PMID 18050488, Free PMC Article
  3. The RNA-binding protein repertoire of Arabidopsis thaliana. Marondedze C, et al. Sci Rep, 2016 Jul 11. PMID 27405932, Free PMC Article
  4. A protein domain-based interactome network for C. elegans early embryogenesis. Boxem M, et al. Cell, 2008 Aug 8. PMID 18692475, Free PMC Article
  5. Interactome analysis of Caenorhabditis elegans synapses by TurboID-based proximity labeling. Artan M, et al. J Biol Chem, 2021 Sep. PMID 34416233, Free PMC Article

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables translation initiation factor activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in cytoplasmic translational initiation IEA
Inferred from Electronic Annotation
more info
  
involved_in formation of cytoplasmic translation initiation complex IEA
Inferred from Electronic Annotation
more info
  
involved_in translation IEA
Inferred from Electronic Annotation
more info
  
involved_in translational initiation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in translational initiation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
part_of eukaryotic 43S preinitiation complex IEA
Inferred from Electronic Annotation
more info
  
part_of eukaryotic 48S preinitiation complex IEA
Inferred from Electronic Annotation
more info
  
part_of eukaryotic translation initiation factor 3 complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of eukaryotic translation initiation factor 3 complex IEA
Inferred from Electronic Annotation
more info
  
part_of eukaryotic translation initiation factor 3 complex, eIF3e IEA
Inferred from Electronic Annotation
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
Eukaryotic translation initiation factor 3 subunit E
NP_492785.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    10640465..10642281 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_060384.8 → NP_492785.1  Eukaryotic translation initiation factor 3 subunit E [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_492785.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O61820
    Conserved Domains (2) summary
    pfam01399
    Location:288 → 393
    PCI; PCI domain
    pfam09440
    Location:5 → 137
    eIF3_N; eIF3 subunit 6 N terminal domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O61820.1

Gene LinkOut

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