rpb-3 DNA-directed RNA polymerase RpoA/D/Rpb3-type domain-containing protein [Caenorhabditis elegans] - Gene

Summary

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Gene symbol: rpb-3
Gene description: DNA-directed RNA polymerase RpoA/D/Rpb3-type domain-containing protein
Primary source: WormBase:WBGene00007971
Locus tag: CELE_C36B1.3
See related: AllianceGenome:WB:WBGene00007971
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable protein dimerization activity. Predicted to contribute to DNA-directed 5'-3' RNA polymerase activity. Predicted to be involved in transcription, DNA-templated. Predicted to be part of RNA polymerase II, core complex. Orthologous to human POLR2C (RNA polymerase II subunit C). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:: chromosome: I

Exon count:: 6

Sequence:: Chromosome: I; NC_003279.8 (8728764..8730054)

Chromosome I - NC_003279.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003279.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

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Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

C36B1.3 (e-PCR)
- UniSTS:307312

C36B1.4 (e-PCR)
- UniSTS:306583

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables DNA-directed 5'-3' RNA polymerase activity	IEA Inferred from Electronic Annotation more info
contributes_to RNA polymerase II activity	IBA Inferred from Biological aspect of Ancestor more info
enables protein dimerization activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in DNA-templated transcription	IEA Inferred from Electronic Annotation more info
involved_in transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info
involved_in transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of DNA-directed RNA polymerase complex	IEA Inferred from Electronic Annotation more info
part_of RNA polymerase II, core complex	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: DNA-directed RNA polymerase RpoA/D/Rpb3-type domain-containing protein

NP_492361.2

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

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Reference assembly

Genomic

NC_003279.8 Reference assembly

Range

8728764..8730054

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_059960.8 → NP_492361.2 DNA-directed RNA polymerase RpoA/D/Rpb3-type domain-containing protein [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_492361.2

Status: REVIEWED

UniProtKB/TrEMBL

Q93338

Conserved Domains (1) summary

cd07031
Location:7 → 274

RNAP_II_RPB3; RPB3 subunit of Eukaryotic RNA polymerase II