U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

rla-1 Large ribosomal subunit protein P1 [ Caenorhabditis elegans ]

Gene ID: 171766, updated on 5-May-2024

Summary

Go to the top of the page Help
Gene symbol
rla-1
Gene description
Large ribosomal subunit protein P1
Primary source
WormBase:WBGene00004409
Locus tag
CELE_Y37E3.7
See related
AllianceGenome:WB:WBGene00004409
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable protein kinase activator activity and ribonucleoprotein complex binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in cytoplasmic translation. Predicted to be located in ribosome. Predicted to be part of cytosolic large ribosomal subunit. Orthologous to human RPLP1 (ribosomal protein lateral stalk subunit P1). [provided by Alliance of Genome Resources, Apr 2022]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
chromosome: I
Exon count:
2
Sequence:
Chromosome: I; NC_003279.8 (2069086..2069575, complement)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Modifier of protein aggregation 4 Neighboring gene ADP-ribosylation factor-like protein 13B Neighboring gene ncRNA Neighboring gene Large ribosomal subunit protein uL15 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_003279.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Abrogation of the CLK-2 checkpoint leads to tolerance to base-excision repair intermediates. Dengg M, et al. EMBO Rep, 2006 Oct. PMID 16964178, Free PMC Article
  2. Distinct modes of ATR activation after replication stress and DNA double-strand breaks in Caenorhabditis elegans. Garcia-Muse T, et al. EMBO J, 2005 Dec 21. PMID 16319925, Free PMC Article
  3. Analysis of acidic peptides with a matrix-assisted laser desorption/ionization mass spectrometry using positive and negative ion modes with additive monoammonium phosphate. Nabetani T, et al. Proteomics, 2006 Aug. PMID 16897684
  4. NatB domain-containing CRA-1 antagonizes hydrolase ACER-1 linking acetyl-CoA metabolism to the initiation of recombination during C. elegans meiosis. Gao J, et al. PLoS Genet, 2015 Mar. PMID 25768301, Free PMC Article
  5. Caenorhabditis elegans operons: form and function. Blumenthal T, et al. Nat Rev Genet, 2003 Feb. PMID 12560808

See all (18) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

Go to the top of the page

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables protein kinase activator activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables ribonucleoprotein complex binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
  
enables structural constituent of ribosome IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in cytoplasmic translation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in translation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of cytosolic large ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytosolic ribosome IEA
Inferred from Electronic Annotation
more info
  
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
  
located_in ribosome IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
Large ribosomal subunit protein P1
NP_001380045.1
  • Partially confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    2069086..2069575 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001393012.1 → NP_001380045.1  Large ribosomal subunit protein P1 [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P91913, Q9GR59
    Conserved Domains (1) summary
    cd05831
    Location:6 → 110
    Ribosomal_P1; Ribosomal protein P1. This subfamily represents the eukaryotic large ribosomal protein P1. Eukaryotic P1 and P2 are functionally equivalent to the bacterial protein L7/L12, but are not homologous to L7/L12. P1 is located in the L12 stalk, with proteins ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P91913.2

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
Molecular Biology Databases
Research Materials
Tools
Miscellaneous